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Biomedical subjects

P Schopflocher

Publications and source records attributed to P Schopflocher.

4 recordsLinked to original sources

Pigmented Paget's disease of the male breast.

Paget's disease of the breast presents as an eczematous lesion of the nipple. Histologically, it is characterized by malignant intraepidermal cells associated with an underlying ductal carcinoma. Paget's disease of the male breast is rare. Although melanin has been found within the malignant cells of Paget's disease, no clinically pigmented lesion has yet been reported. We present a case of pigmented Paget's disease of the male breast and review the pathogenesis of this disease.

Aged↗

Cutaneous metastases from carcinoma of the cervix.

Metastases to the skin from internal malignant neoplasms are an uncommon and often preterminal event. Cutaneous metastases from a carcinoma of the uterine cervix, however, have rarely been reported, even in the advanced stages of the disease. A patient was initially seen with cutaneous metastases and was found to have an extensive tumor in the pelvis, which proved to be a squamous cell carcinoma arising in the cervix.

Abdomen↗

Pityriasis rosea in a patient with epidermolysis bullosa dystrophica.

A patient with clinical and histologic features of epidermolysis bullosa dystrophica-recessive (EBD-R) developed superimposed clinical lesions of pityriasis rosea (PR). Electron microscopy showed distinct "blebbing" of basal cells at the basement membrane zone in clinically normal skin of a non-predilected area, as well as in scarred skin from a predilected area and a lesion of PR. An increased susceptibility of the basement membrane zone to proteolytic enzymes is suggested as a possible hypothesis to explain these observations.

Adult↗

Hidrotic ectodermal dysplasia with diffuse eccrine poromatosis.

Eccrine poromatosis (EP) of remarkable severity has been observed in a patient with hidrotic ectodermal dysplasia (HED), a member of the kindred originally described by Clouston. Neither the EP nor its association with HED has been previously reported.

Adult↗