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Biomedical subjects

P Schubarth

Publications and source records attributed to P Schubarth.

9 recordsLinked to original sources

[ARDS in plasmodium vivax malaria].

Acute renal failure, disseminated intravascular coagulation, ARDS, hypoglycaemia, coma or epileptic seizures are manifestations of severe Plasmodium falciparum malaria. On the other hand, vivax malaria or benign tertian malaria is usually free from complications. In the present report we describe a case of acute tertian malaria with a severe and complicated course. In this situation bacterial coinfection should always be suspected and treated empirically with broad-spectrum antibiotics, until the results of cultures are available. Mixed plasmodial infection (P. vivax and P. falciparum) must be excluded by repeated and meticulous examination of blood smears. Newer techniques such as PCR processing or ParaSight F Test are mentioned.

Adult↗

[Fever upon return from the tropics].

Malaria is the most important dangerous febrile disease in patients returning from the tropics. Falciparum malaria can occur up to one year after leaving the tropics, tertian and quartan malaria even after many years. Laboratory diagnosis is made by thick and thin blood smear. Tertian and quartan malaria are treated by chloroquine , falciparum malaria by quinine, mefloquine or halofantrine.

Adult↗

Disappearance of a large mediastinal pseudocyst in a patient with chronic alcoholic pancreatitis after total parenteral nutrition.

OBJECTIVE: To report the unusual case of a mediastinal pseudocyst in a patient with chronic pancreatitis, which resolved after conservative treatment. PATIENT: A 59-year-old patient with alcohol-induced chronic pancreatitis and a large mediastinal pseudocyst. INTERVENTIONS: Bowel rest and total parenteral nutrition for 4 weeks. MAIN OUTCOME MEASURES: The pseudocyst resolved completely. CONCLUSION: Conservative treatment is a valuable option in patients with chronic pancreatitis presenting with a mediastinal pseudocyst, but close supervision is mandatory.

Alcoholism↗

[Conventional or complementary medicine: what criteria for choosing do patients use?].

Only a few studies have investigated in depth the motives behind the choice of conventional or complementary medicine. While some studies document failures or general mistrust of conventional medicine as the main reasons for turning to complementary medicine, others conclude that the decision to try alternative medicine is not necessarily due to disappointment with conventional medicine but rather an endeavour to do everything possible for one's own health. Patients regard complementary medicine indeed as a complement. Longer-lasting consultation and a better doctor-patient relationship are occasionally mentioned as favourable aspects of complementary medicine. Other motives are a critical attitude to modern civilization and the growing symbolic value of health. The choice may be related to the nature of the disease. Depending on the patient population involved, complementary medicine is used for either more difficult or simpler cases. As a general rule it is the chronic problems that are dealt with by complementary medicine. Users of complementary medicine cannot be regarded as a homogeneous group. Nevertheless, one Swiss study concludes that users of complementary medicine tend to be female, with higher education, from the upper middle class and aged between 30 and 50. They have postmaterialistic value priorities, holistic interpretative models of health and disease, and want to share in decision-making on treatment questions. Approaches and contexts of individual studies differ and the study populations of individual investigations are sometimes questionable. This means that some results are to be treated with caution. The literature under review rarely refers to cultural and social aspects as possible factors, and processes are likewise rarely investigated. Only one study presents behaviour in sickness as a social process which reveals how people perceive, interpret and respond to health problems. In conclusion, the sociological theories and findings involved in the entire question area are briefly outlined.

Adult↗

[Vitamin deficiency in developing countries].

Vitamin A deficiency is frequent in the tropics. It causes xerophthalamia, which, in severe cases, can develop into corneal ulceration, keratomalacia and blindness and increases morbidity and mortality of infectious diseases in infants and children. Vitamin A deficiency can be reduced by the promotion of a nutrition rich in vitamin A, by fortification of food with vitamin A and by high-dose vitamin A supplementation. Other vitamin deficiency disorders are rare or occur only in limited areas or in disadvantaged people. In refugee camps, scurvy, beriberi, pellagra and xerophthalamia occur. Travelers from developed countries are rarely affected by vitamin deficiency disorders, if they eat regularly the large variety of fruits and vegetables usually available in tropical countries. Their vitamin stocks are anyhow sufficient for several weeks.

Adult↗

[Malaria: the most important emergency in subjects returning from the tropics].

Malaria is the most important emergency in people returning from tropical countries. Falciparum malaria may lead to coma and death within a few hours. The symptoms are generally not specific. A history of travelling in tropical countries is the most important factor in diagnosis. In the case of fever after a journey in the tropics, malaria must always be considered in the first place. Laboratory diagnosis is established by finding of plasmodia in blood smears. Vivax, ovale and quartan malaria is treated by chloroquine. Falciparum malaria is usually treated by mefloquine, Fansimef, quinine or quinidine.

Animals↗

Epidemiological experience in the mission of the United Nations Transition Assistance Group (UNTAG) in Namibia.

Epidemiological data have rarely been generated during United Nations (UN) missions to Third World countries, even in situations where there is hardly any combat involvement. Continuous surveillance was therefore carried out during the 12-month stay of UN personnel in Namibia in 1989-90. In this population of 7114 persons, mostly young men, the mortality rate was 255 per 100,000; death was mainly due to traffic accidents. Hospitalization was chiefly because of fever of unknown origin or trauma. Repatriation to the country of origin was necessary in 46 patients, frequently for psychiatric reasons including alcoholism. Over this one-year period there were, on average, 2.7 new consultations per person for treatment (mostly for dental problems), and 0.8 per person for prophylactic measures. The extremely high mortality due to traffic accidents indicates a need for prevention. In the selection process for future missions, more emphasis should be given to the psychological and dental health of volunteers. All military contingents and civilian groups should learn about effective preventive measures prior to their arrival, and adhere to them.

Accidents, Traffic↗

Thiabendazole vs. albendazole in treatment of toxocariasis: a clinical trial.

Between 1986 and 1988, 34 patients (age range six to 83 years) with visceral or ocular larva migrans were randomly assigned to a five-day treatment with thiabendazole 2 x 25 mg kg-1 day-1 (15 patients) or albendazole 2 x 5 mg kg-1 day-1 (19 patients). On the fifth treatment day, six patients (40%) in the thiabendazole group and 11 patients (58%) in the albendazole group showed excellent or good drug tolerability. Efficacy of treatment was assessed after 30 weeks (range six to 56 weeks). In the thiabendazole group, median eosinophilia remained at 14% and four patients (27%) were clinically cured. In the albendazole group, the median eosinophilia decreased from 10 to 3.5% and six patients (32%) were clinically cured. We recommend albendazole for treatment of visceral and ocular larva migrans with a minimum dose of 10 mg kg-1 daily for five days.

Adolescent↗