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Biomedical subjects

P Simoens

Publications and source records attributed to P Simoens.

77 records · Page 5Linked to original sources

Structure of the prostate and the pelvic urethra in barrows and the changes induced by diethylstilbestrol.

The anatomical and light microscopical structures of the pelvic urethra with the surrounding prostate were investigated in male pigs, which were castrated early in life and examined at slaughter weight. The general structure was regular in the caudal part, but was irregular in the cranial part. In the prostate each lobule contained a cell-rich stroma, which surrounded several glandular tubules and a few prostate ductules. The tubules were lined by low columnar cells and some reserve cells, the ductules by a low two-layered epithelium and the urethra by a transitional epithelium. Small differences in the gland structure and urethral epithelium were observed between the cranial and caudal part. Subcutaneous injection of diethylstilbestrol provoked metaplasia of the epithelium of the urethra and the ducts, while the peroral administration of diethylstilbestrol in combination with methyltestosterone resulted in an increased number of glandular tubules.

Animals↗

Arterial supply to the optic nerve and the retina of the sheep.

The arterial supply of the optic nerve and the retina of four fetal and ten adult sheep was studied by various injection techniques and verified by histological examination in one neonatal lamb. The optic nerve was supplied by the rostral cerebral artery, including the rostral hypophysial artery, the internal ophthalmic artery and its chiasmatic rete, and recurrent branches from the choroidoretinal arteries. The retinal arterioles were supplied by the choroidoretinal arteries, which coursed rostrally in the external sheath of the optic nerve and perforated the area cribrosa of the sclera. The dorsal choroidoretinal artery arose variably from the external ophthalmic artery and its terminal branches. It supplied the rostral portion of the optic nerve, the choroid and, except in one sheep, all retinal arterioles. The ventral choroidoretinal artery arose variably from the anastomotic branch between the external and internal ophthalmic arteries. It supplied the rostral aspect of the optic nerve and the choroid and continued in the fetal lambs as the hyaloid artery. In one specimen it also supplied the lateral retinal arterioles. There was no evidence for a central retinal artery and a continuous arterial circle of the optic nerve.

Animals↗