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P Skyba

Publications and source records attributed to P Skyba.

5 recordsLinked to original sources
PubMed2006

Blood pressure and heart rate variability response to noninvasive ventilation in patients with exacerbations of chronic obstructive pulmonary disease.

Sympathetic activation and parasympathetic withdrawal are commonly observed during acute exacerbations of chronic obstructive pulmonary disease (COPD). We have demonstrated previously that noninvasive positive-pressure ventilation (NPPV) improves parasympathetic neural control of heart rate in patients with obstructive sleep apnea. We hypothesized that NPPV may exert such beneficial effects in COPD as well. Therefore, we assessed the acute effects of NPPV on systemic blood pressure and indexes of heart rate variability (HRV) in 23 patients with acute exacerbations of COPD. The measurements of HRV in the frequency domain were computed by an autoregressive spectral technique. The use of NPPV resulted in significant increases of oxygen saturation (from 89.2+/-1.0 to 92.4+/-0.9 %, p<0.001) in association with reductions in systolic and diastolic blood pressures and heart rate (from 147+/-3 to 138+/-3 mm Hg, from 86+/-2 to 81+/-2 mm Hg, from 85+/-3 to 75+/-2 bpm, p<0.001 for all variables), and increases in ln-transformed high frequency band of HRV (from 6.4+/-0.5 to 7.4+/-0.6 ms(2)/Hz, p<0.01). Reductions in heart rate and increases in ln-transformed HF band persisted after NPPV withdrawal. In conclusion, these findings suggest that NPPV may cause improvements in the neural control of heart rate in patients with acute exacerbations of COPD.

Aged↗
PubMed2004

Interfacial energy of the superfluid 3He a-B phase interface in the zero-temperature limit.

We have measured the surface energy of the interface between the A and B phases of superfluid 3He in the low temperature limit at zero pressure. Using a shaped magnetic field, we control the passage of the phase boundary through a small aperture. We obtain the interphase surface energy from the over- or undermagnetization required to force the interface through the aperture in both directions, yielding values of the surface tension and the interfacial contact angle. This is the first measurement of the interfacial energy in high magnetic fields and in the zero-temperature limit.

Journal Article↗
PubMed2003

Spin precession waves in superfluid 3He-B.

Spin precession waves of homogeneously precessing domains (HPD) in superfluid 3He-B have been studied at 11 bars and temperatures down to 0.45T(c). The waves were excited by an alternating longitudinal magnetic field with an axial symmetry, applied as a small perturbation ranging from 1 nT up to a few micro T. When the spin precession wave is excited, two nuclear magnetic resonances simultaneously coexist: first, the high frequency resonance used for excitation of the HPD, and, second, the low-frequency resonance of the HPD wave mode. We report the first experimental evidence of the nonlinear behavior of low-frequency precession spin wave modes of the continuously maintained HPD.

Journal Article↗
PubMed2000

Primary and secondary nucleation of the transition between the A and B phases of superfluid 3He

We have studied nucleation in superfluid 3He across the A-B phase transition driven by a magnetic field, in a controllable environment at very low temperatures. Both B-->A and A-->B secondary nucleation appear to be governed by the survival of pockets of the new phase trapped at surfaces. We find that, at fields near B(AB), primary A-->B nucleation cannot be triggered by ionizing or neutron irradiation even at very high intensities. In our cell primary A-->B nucleation can only be triggered externally by mild mechanical shock.

Journal Article↗