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Biomedical subjects

P Solc

Publications and source records attributed to P Solc.

At least 19 recordsLinked to original sources

[Chronic dyspepsia. Basic classification based on symptoms and relation to gastrointestinal intolerances and diseases].

BACKGROUND: For expedient examination and treatment of chronic dyspepsias initial classification into groups which do not overlap in the main signs is necessary. Such a classification is lacking. The authors used a classification according to bitter or solely acid regurgitations and vomiting and their absence and according to the frequency and occurrence of bowel movements in the course of the day. METHODS AND RESULTS: In a group of 366 subjects (92 men and 274 women) aged 19 to 76 years (mean 52.3 years) readily available data were evaluated statistically (chi square and agreement of two relative frequencies): symptomatology, objective finding, gastrointestinal intolerance (IT). 116 statistically significant relationships were revealed and were divided into four groups: 1, group with bitter manifestations in the morning on fasting and during the night with a relation to milk IT (less with lactose IT) and postprandial diarrhoea. 2. group with bitter manifestations after a meal and in daytime, related to biliary disease and IT of fat. 3. group with solely acid manifestations associated with IT of vinegar, alcohol, gastroaggressive drugs and oligosaccharides and peptic ulceration also in remission. 4. group without regurgitations and vomiting which needed further classification: relatively tolerant of fat but not milk. This group has a characteristic sub-group of subjects with a quiescent stage after cholecystectomy. This sub-group is a "negative" of the properties of group 3. CONCLUSIONS: In the patients four defined groups of dyspepsias were defined associated with manifestations of actual intolerances of foods, savouries and drugs. Three of them are associated with antiperistaltic phenomena in the upper gastrointestinal tract.

Adult↗

Barium granuloma of gastroesophageal junction causing progressive dysphagia.

The authors observed for the first time a barium granuloma of the gastroesophageal junction that led to progressive dysphagia. The patient was fully cured by a radical excision of the granuloma and by esophagofundoplasty. The most probable way of development of the granuloma is thought to be by the author the retention of barium sulphate in a peptic subcardial ulcer during the X-ray examination, which did not recognize it.

Barium Sulfate↗

[Course and results of the Karlsbad cure after cholecystectomy].

The course and the result of a cure in Karlovy Vary was pursued in 148 cholecystectomized patients. With the exception of 5 patients who were transferred to the surgeon after a bilious attack and 1 patient with malignoma of the biliary ducts 142 patients spoke of a subjective improvement at the end of the cure. The cure passed systematically in 50 patients with slight biliary complaints. In more considerable complaints, however, in 23 of 98 patients a bilious attack occurred during the cure, which made necessary the surgical intervention in 5 patients. Relapsing fever episodes could be clinically governed in 41 patients. Antibiotics remained without any effect in 41 patients. The values of the alkaline serum phosphatase and gamma-glutamyl-transpeptidase normalised only in 8 of this group, not, however, in 45 patients. The results altogether refer to the fat that the indications to a cure in Karlovy Vary must be made more carefully. After a cholecystectomy they should be recommended only then, when the biliary ducts eventually were cleant up. In these cases the only cholangiitis is no contraindication. The treatment may be supplemented by antibiotics.

Adult↗