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Biomedical subjects

P Squire

Publications and source records attributed to P Squire.

6 recordsLinked to original sources
PubMed1993

Comparison of mechanical properties of human, bovine bone and a new processed bone xenograft.

The study compared the mechanical properties of human bone, fresh bovine bone and a new highly purified bone xenograft: T650 (Lubboc-Laddec). Destructive, compressive tests were performed to determine Young's modulus and ultimate strength, with a constant deformation rate of 0.025 mm min-1. The stress-strain curves obtained from all the non-human specimens especially the T650, did not differ significantly from those observed with human bone. Human and fresh bovine samples presented a significantly different Young's modulus. The T650 samples, depending upon their trabecular texture (dense or medium) also differed significantly from each other (132.9 +/- 52.3 versus 80.0 +/- 37.3 MPa, P < 0.05). Their moduli were similar to those of bovine and human cancellous bone, respectively (117.49 +/- 61.53 versus 77.36 +/- 54.96. P < 0.05). The ultimate strength of T650 dense (9.6 +/- 3.7 MPa) was similar to bovine (8.5 +/- 4.2 MPa) and human bone (8.78 +/- 5.2 MPa): the T650 medium (5.9 +/- 2.8 MPa) was significantly different from the other specimens.

Aged↗
PubMed1992

Effect of electrical stimulation superimposed with isokinetic contractions.

Previous studies have considered the effects of the superimposition of electrical stimulation (ES) upon maximal voluntary contraction (MVC) under isometric conditions. This investigation considered these effects using isokinetic muscle action. Eleven males, non athletes, volunteered for the experiment. Isokinetic torque for extension of the right knee was measured by means of a Cybex 340 using two speeds of movement, 12 degrees/s and 30 degrees/s. Torque was measured at 5 degrees increments (from 100 degrees flexion to full extension) under conditions of MVC alone and MVC+ES. Stimulation was provided by means of a bi-phasic, symmetrical, square wave with a pulse width of 600 mu. Frequency of stimulation was either 30 Hz or 80 Hz. It was found that the pattern of torque production was unaffected by the application of ES. Peak torque values at both speeds were significantly lower when ES was applied at both frequencies compared to MVC alone. This inhibitory effect was found to extend throughout the middle range of movement. This tended to be more pronounced with the 80 Hz frequency. In general these findings were in agreement with those reported previously for isometric conditions. Possible explanations for these results include the inability of ES to recruit more motor units than MVC alone; the limitations of the subjects to tolerate a current of a sufficiently high intensity to elicit a stronger contraction, possibly due to lack of familiarization with these forms of muscle action; and the characteristics, especially pulse width, of the stimulating current.

Adolescent↗