PubMed Health⌕ Search

Biomedical subjects

P Strachan

Publications and source records attributed to P Strachan.

4 recordsLinked to original sources

Acceptability and uptake of a community-based flu immunisation programme.

OBJECTIVE: To evaluate a community based influenza immunisation programme in terms of patients' and primary care professionals' satisfaction and uptake of immunisation. DESIGN: Surveys were conducted which compared the experiences and opinions of groups of staff and patients who had experienced the programme with groups where general practice was responsible for immunisation arrangements. SETTING: Primary care. SUBJECTS: Patients eligible for influenza immunisation and general practice staff involved in providing immunisation. RESULTS: A good response was obtained from patients (82.2%:2,900) and general practices (83.3%:55). Patients from both programme and comparison groups reported high levels of satisfaction with flu immunisation arrangements. Preferences expressed tended to coincide with patients' experiences of arrangements. Around 40% of both groups desired information. A minority of unvaccinated patients (more programme patients than comparators) expressed difficulties in accessing clinics. There were both advantages and disadvantages for general practices involved in the programme. Although time consumed in giving injections was less for programme staff, they reported substantial time spent on programme-related administration and dealing with patients' queries. Programme figures indicate uptake of 53.8% (not including those vaccinated elsewhere). Survey results show that 58.5% of programme patients who responded were vaccinated. CONCLUSIONS: In light of recent Scottish Executive Health Department guidance, experiences of this programme may be of interest to those contemplating Local Development Schemes for flu immunisation. Findings highlight the dilemma between potential economies of scale and continuity of care for patients.

Chi-Square Distribution↗

GFRalpha-4, a new GDNF family receptor.

GFRalpha-1, GFRalpha-2, and GFRalpha-3 constitute a family of structurally related, glycosyl-phosphatidylinosital-linked, cell surface proteins, two of which, GFRalpha-1 and GFRalpha-2, are components of the receptor complex for the neurotrophic factors GDNF and neurturin, respectively. By screening an embryonic chicken brain cDNA library with a GFRalpha-1 probe at low stringency, we isolated cDNAs encoding an additional member of the GFRalpha family, GFRalpha-4. The nucleotide sequence predicts a 431-amino-acid secreted protein that is more closely related to GFRalpha-1 and GFRalpha-2 than to GFRalpha-3. GFRalpha-4 mRNA is expressed in distinctive patterns in the brain and several other organs and tissues of the chicken embryo. Our findings extend the family of GFRalpha proteins and provide information about the tissues in which GFRalpha-4 may function during development.

Animals↗