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Biomedical subjects

P T Hung

Publications and source records attributed to P T Hung.

11 recordsLinked to original sources
PubMed1992

THC:YAG laser sclerostomy with mitomycin subconjunctival injection in rabbits.

We performed sclerostomy using THC:YAG laser (thulium, holmium, chromium doped YAG crystal) and subconjunctival injection of mitomycin soon after the filtering process in rabbits to observe the lowering effect of intraocular pressure(IOP) and filtering bleb formation. A 1-mm conjunctiva wound was made 12 mm away from the sclerostomy site to allow the entry of the optic probe for delivering energy. Forty-eight rabbits were divided into 3 groups. After sclerostomy, Group I received 0.2 ml normal saline subconjunctival injection and Group II and III received 0.2 ml mitomycin injection of 0.1 and 0.2 mg/ml respectively. One eye of each rabbit was randomly selected for the experiment while the fellow eye served as control. The bleb lasted 1.4 +/- 0.5 days (or 1 to 2 days) in Group I, 8.5 +/- 4.5 days (or 4 to 17 days) in Group II and 15.4 +/- 10.9 days (or 4 to 37 days) in Group III. The IOP lowering effect was significantly enhanced in Group III. The postoperative complication was minimal corneal punctate erosion in the mitomycin group, but all of them, however, resolved within one week. The results demonstrated that mitomycin is effective in prolonging the filtering effect produced by the THC:YAG laser.

Animals↗
PubMed1991

Ocular pulse amplitude in myopia.

We studied the ocular pulse amplitude of myopic patients by using Alcon Pneumotonography. One hundred and eighty-eight cases (376 eyes) were enrolled in this study. The results revealed that the higher the myopia the lower the ocular pulse amplitude. The pulse amplitude has high correlation with refractive error and axial length, but poor correlation with scleral rigidity, intraocular pressure and corneal curvature. As the ocular pulse amplitude is generated by the choroidal blood flow, these results may reflect circulatory disturbance in the development of myopia.

Adolescent↗
PubMed1990

Provocation and medical treatment in post-iridectomy glaucoma.

Residual glaucoma after an iridectomy in primary angle-closure glaucoma, or so called post-iridectomy glaucoma, is rather well recognized recently. It is also realized that probably different mechanisms in addition to the pupillary block mechanism co-exist in the same glaucoma eye. The efficacy of medical treatment for such glaucoma was evaluated by dark prone provocative test after timolol or pilocarpine topical instillation to compare with non-medication as control in 72 iridectomized eyes. The results revealed pilocarpine medication has only six eyes positive (8.3%) and significantly prevents IOP elevation in the test while timolol has no significant effect (23 eyes positive, 31.9%) when both were compared with the control study (31 eyes positive, 43.1%). The results may also suggest additional different mechanisms involved in this glaucoma.

Administration, Topical↗
PubMed1979

Provocation and mechanism of angle-closure glaucoma after iridectomy.

Dark room tests and prone-position tests in a lighted room and in a dark room were carried out on 64 eyes in 32 normal patients and 37 eyes of 30 patients that had undergone complicated iridectomy. Among the iridectomized eyes, the dark room tests and the prone-position test in lighted room caused elevation of intraocular pressure of more than 8 mm Hg in only 2.7% and 16.2%, respectively. Nearly 60% of the eyes showed positive results when the prone-position test was performed in a dark room. Our findings may provide experimental support for the theory of direct lens block as an angle-closure mechanism.

Darkness↗
PubMed1979

Cataract extraction in glaucoma.

Cyclodialysis lens extraction or cyclodialysis canalicular trabeculectomy lens extraction in one eye and cataract extraction in the fellow eye were performed in 24 glaucoma patients. The combined procedure follow-up was from five to 12 years in the first group, two to four years in the second group, and from three to ten years in the control group. The 50% success rate of cyclodialysis lens extraction can be enhanced with no significant increase in surgical morbidity or postoperative complications by performing a cyclodialysis canalicular trabeculectomy where the disinsertion of the scleral spur is carried out under direct visualization.

Aged↗
PubMed1977

Surgical repair of leaking blebs.

To repair a ruptured filtering bleb, we used the conjunctiva alone, or combined with its undissected Tenon's fascia, to cover the sclerostomy site. We used mattress sutures to thread the new flap into a vertical corneal groove anterior to the sclerostomy, creating a firm, nonretracting but still sufficiently "porous" cover that maintained filtration and resisted infection and perforation. Seven of eight cases of ruptured filtering blebs have been successfully repaired in this manner with the maintenance of adequate filtration.

Adult↗
PubMed1977

Further observations on eccentric perilimbal suction cup application.

Absence of an anemic, cystic bleb site, as well as reduced fluorescein fluorescence in this area after transcleral fistulizing surgery, infer failure. One method to create or augment bleb formation in suitable eyes is with the use of eccentric suction. This method creates localized ocular message, mobilizes conjunctiva and episclera, and provides a quantitative measure of bleb function.

Adult↗
PubMed1975

Epidemic hemorrhagic keratoconjunctivitis.

A new type of acute keratoconjunctivitis developed throughout Southeast Asia, beginning in Singapore in the summer of 1970. It was highly contagious and probably was transmitted from person to person by the hand to eye route. Sixteen cases, diagnosed by viral isolation or serologic study, or both, were subjected to detailed clinical observation. The characteristic features included a short incubation period of one or two days, watery or serous discharge, subconjunctival hemorrhage, and pinpoint superficial keratopathy. The disease usually resolved rapidly within one to two weeks without sequelae.

Adolescent↗