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Biomedical subjects

P Thyagarajan

Publications and source records attributed to P Thyagarajan.

7 recordsLinked to original sources

What influences medical students' choice of surgical careers.

BACKGROUND: Recent emphasis in medical education has been to encourage students to pursue primary care careers. This could have a negative impact on applications to surgical residencies. METHODS: To determine what factors are most influential for a student to pursue a surgical career in spite of this environment, third- and fourth-year medical students were surveyed with a 40-item questionnaire. RESULTS: The response rate was 37% (76/205). Those students considering a career in surgery were more likely than their counterparts to be motivated by role models (P <.006), career opportunities (P <.006), and academic opportunities (P <.013) in surgery. They were less likely than their counterparts to be discouraged from surgery on the basis of lifestyle (P <.001), time commitment (P <.001), call schedules (P <.001), or residency length (P <.028). No differences regarding financial rewards, research opportunities, or intellectual challenges were seen between the groups. Neither race nor sex had a significant role in the selection of surgery as a career. CONCLUSIONS: The data suggests that students are more likely to be influenced to pursue surgical careers by offering early exposure to positive role models and career and academic opportunities in surgery. Knowledge of these influences on student career choices should help surgical educators attract and maintain student interest in surgical careers.

Career Choice↗

Distribution of lactic dehydrogenase in X-irradiated tissues.

Exposure to whole-body X-irradiation in rats causes a marked increase in total lactic dehydrogenase (LDH) activity and decrease in H-LDH/M-LDH ratio in serum and tissues, the maximum effect being observed on the 8th post-irradiation day. While there is an elevation of M-LDH isoenzyme, H-LDH remains relatively constant. Studies on incorporation of DL-leucine-l-14C into heart LDH isoenzymes also revealed increased biosynthesis of M-LDH isoenzyme. This indicates that an adaptive mechanism is operative in the X-irradiated rats, whereby, in order to augment anaerobic glycolysis, synthesis of M-LDH is stimulated. Administration of the radioprotector cystamine does not alter the effects of X-irradiation on serum LDH activity.

Animals↗