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P Tison

Publications and source records attributed to P Tison.

13 recordsLinked to original sources

[Our surgical experience of 20 extracochlear implantations on the oval window with transcutaneous approach].

While multichannel implants can produce far better results than single-channel implants, the results of a multichannel implantation are impossible to predict accurately preoperatively. Single-channel implants, which produce average and constant results, still have a major merit in that their cost is much lower. Since extracochlear implantation with transcutaneous approach is innocuous, we have been promoting this type of implantation as a temporary procedure until much more effective systems are found in the future, or as a definitive implantation.

Deafness

[Atypical implants].

There is theoretically no major surgical problem for implantation. The basic techniques all include on an approach through the windows. The authors describe a solution (which has already been used previously) for cophotic hollowing-out cavities, with a suprapetrosal way and an approach on the hidden aspect of the cochlea. The transcutaneous passage can be displaced from the ear lobe to a depression of the auricle.

Cochlear Implants

[Tinnitus and implants].

The experience with cochlear implantation at Avicenne hospital prompted us to carry out a retrospective study on tinnitus in a population of operated patients. Improvement or disappearance of the symptoms was noted in all cases. These results, which partly match those found in the literature, are probably produced by rehabilitation inhibiting the "deafferentation" mechanisms in analogy with pain phenomena. In some precise cases, which are described, they led us to proposing implantation even though the main, if not sole, complaint of the patient was tinnitus.

Acoustic Stimulation

[Deafness and sarcoidosis].

The cochleovestibular tract is seldom involved by sarcoidosis (about 50 cases have been described since 1948). As a clinical expression of sarcoidosis, deafness is fluctuant in 50% of all cases, bilateral, and most often associated with facial palsy and uveitis, the vestibular reflexes being reduced. The histological studies demonstrate lesions at all levels from the cochlea to be brain stem, but the main mechanism is an infiltration of the arachnoid vessels. The prognosis of sarcoidosis deafness is usually poor in spite of corticosteroid therapy. This paper is illustrated by 3 cases observed in Avicenne Hospital.

Adult

[Value of Gore Tex in the reconstruction of the nasofrontal canal].

Surgical technic used in treatment of chronic frontal sinusitis is described, and the interest emphasized of the employ of fragments of Gore Tex prosthetic fragments for calibration and maintenance of permeability of the newly formed nasofrontal canal. Their perfect tolerance allows them to be left in place and their permeability can be surveilled by CT scan imaging or fibroscopy.

Blood Vessel Prosthesis

Blood pressure, 5-OH indoleacetic acid, and vanilmandelic acid excretion and blood platelet aggregation in hypertensive patients treated with ketanserin.

Ketanserin, a new selective 5-HT2-serotonergic antagonist, was used to: confirm its hypotensive efficacy in acute and long-term treatment, determine its influence on the influence on the metabolism of serotonin (5-HT) and catecholamines, and elucidate their mutual relationship. Ketanserin was given intravenously to 10 patients with hypertensive crisis or resistant hypertension and orally to 15 patients with mild to severe hypertension for 1 year. Blood pressure, heart rate, 24-h urinary excretion of vanilmandelic acid (VMA; the major endproduct of catecholamines) and of 5-hydroxyindoleacetic acid (HIAA; the endproduct of serotonin metabolism), and platelet aggregation were measured. In doses normalizing blood pressure and platelet aggregation, ketanserin administered to hypertensive patients either intravenously in acute treatment or orally in chronic treatment caused: (a) decreased HIAA excretion (more marked in chronic than in acute treatment) and (b) simultaneous decrease in VMA excretion. It is concluded that the decisive sites of ketanserin action are the 5-HT2 receptors of platelets. The compound reduces platelet aggregation and the release of 5-HT, its metabolism, and, hence, the excretion of HIAA. The action of ketanserin on 5-HT2 receptors of vascular smooth muscle participates in the hypotensive effect of the drug but does not explain the decreased excretion of HIAA and VMA.

Adult