Early detection of microalbuminuria by four different immunochemical methods.
Explore the source record for details and available documents.
Albuminuria↗
Biomedical subjects
P Tuengler
Publications and source records attributed to P Tuengler.
New immunodiagnostic systems.
Two new systems for homogeneous plasma protein immunoassays, the Behring Nephelometer System and the Behring TurbiTimeSystem, as well as the Behring ELISA System for heterogeneous enzyme immunoassays are described.
Blood Proteins↗
Studies on the active center of D- and L-lactate dehydrogenases using oxamate-diaminohexyl-Sepharose affinity chromatography.
Vertebrate and invertebrate L-lactate dehydrogenases (L-lactate:NAD+ oxidoreductase, EC 1.1.1.27) are effectively bound to oxamate-diaminohexyl-Sepharose, whereas several D-lactate dehydrogenases (D-lactate:NAD+ oxidoreductase, EC 1.1.1.28) do not bind to the same Sepharose. One explanation for our findings is that the enzymes' substrate is oriented in a reversed manner in the active center of the D- and L-lactate dehydrogenases.
Animals↗
Calculated molecular weight of proteins in high ionic strengths: contribution of the apparent isopotential specific volume.
Explore the source record for details and available documents.
Animals↗
Enhanced heat, alkaline and tryptic stability of acetamidinated pig heart lactate dehydrogenase.
Modification of 17 from 24 lysine residues in pig heart lactate dehydrogenase (L-lactate: NAD+ oxidoreductase, EC 1.1.1.27) with methyl aceimidate yields an enzyme derivative with enhanced stability toward meat and alkaline denaturation as well as tryptic digestion. The specific activity of the modified enzyme is only slightly reduced
Acetamides↗
Search for millimeter microwave effects on enzyme or protein functions.
Recent observations of nonthermal, resonant biological responses to weak millimeter microwave irradiation have led us to investigate whether similar influences exist on enzymatic functions in vitro. We chose (i) the reduction of ethanol in the presence of alcohol dehydrogenase and (ii) the cooperative binding of oxygen on hemoglobin. Using an irradiation intensity near 10 mW/cm2 the frequency was continuously varied from 40 to 115 GHz with a resolution of a few MHz. No microwave influences were detectable within our experimental sensitivity of about 0.1% of the reaction rate in (i), or of the amount of bound oxygen at half saturation in (ii).
Alcohol Oxidoreductases↗