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Biomedical subjects

P U Fechner

Publications and source records attributed to P U Fechner.

At least 91 records · Page 5Linked to original sources

[Long-term results of laser-trabecular-puncture (author's transl)].

A report on 38 eyes with glaucoma simplex that were treated by laser-trabecular-puncture 2 years ago is given. By this method one attempts to perforate the trabecular meshwork by means of a laser beam. Gonioscopy revealed that the pores had become occluded by scar tissue and goniosynechiae. In only 3 eyes (7.9%) was the intraocular tension lowered. The hypothesis is made, that in these cases contracture of scar tissue in the iris tissue led to a pull on the trabecular network and hence to an improvement of liquor drainage.

Aged↗

[Trabeculectomy, a fistulizing operation with refixation of the scleral flap (author's transl)].

The study is based on 122 trabeculectomies performed on eyes with open angle glaucoma (glaucoma simplex). Satisfactory control of intraocular pressure was achieved in 80 to 90 percent of the eyes. Refixation of the scleral flap into its bed with sutures is an essential feature of the operation. This provides a valve mechanism. As a rule the valve does not open postoperatively unless the intraocular pressure has again reconstituted itself to some extent. Clinical advantages are: 1. Generally the anterior chamber has normal depth at the first postoperative day. 2. Postoperative hypotony is rare. 3. Usually postoperative inflammation is of low degree and of short duration. 4. Short hospitalisation. At present trabeculectomy is the authors operation of choice in eyes with glaucoma simplex.

Aged↗

Optic nerve hypoplasia.

Optic nerve hypoplasia is rarely met in otherwise normal eyes. Three unilateral cases of patients with small optic disks, reduced visual acuity, and convergent squint on the affected eye are presented. The anomaly is probably caused by failure of development of the ganglion cell layer of the retina causing a small optic nerve head with normal central vessels. Inheritance or induction by drugs could not be found in our cases.

Child↗

Worst-Fechner biconcave minus power phakic iris-claw lens.

OBJECTIVE: Evaluation of long-term results of correction of high myopia by implantation of a biconcave Worst-Fechner minus power iris-claw lens into phakic eyes. METHODS: One hundred and twenty-seven eyes of 70 patients were implanted with the phakic IOL between November 1986 and November 1991. The mean preoperative spherical equivalent refraction was -14.29 +/- 5.77 D (range -5.00 to -31.75 D). The total population decreased from 127 to 68 eyes (53.5%) at the 8-year examination. By this time, 26 of the 70 patients (37%) had been lost to follow-up for unknown reasons. Corneal endothelial density was estimated by comparing the image gained by non-contact specular microscopy with a graduated reticule (Karickhoff method). RESULTS: At the 6-month examination, mean deviation of achieved from calculated refractive correction was +0.52 +/- 1.46 D (range -2.25 to +6.50 D). Seventy-seven eyes (62.1%) deviated 1.00 D or less, and 15 eyes (12.1%) deviated by more than 2.00 D from the calculated correction. A refractive outcome of +/- 1.00 D was attempted in 68 eyes (54% of the 124 eyes) and was achieved in 51 eyes (75%). Mean spectacle-corrected visual acuity preoperatively was 0.54 +/- 0.27 (range 1.20 to 0.05). At the 6-month examination it was 0.73 +/- 0.3, and by the 8-year examination had decreased to 0.65 +/- 0.26. Statistical analysis of corneal endothelial cell density revealed a significant correlation of endothelial cell loss with age (> or = 45 years), anterior chamber depth (< or = 3.4 mm), and IOL power (> or = -11.00 D). Seventeen eyes (13.4%) had a decrease in endothelial cell density and projection to 8-year follow-up resulted in a decrease in 27% of eyes. Four eyes needed a penetrating keratoplasty. CONCLUSION: Implantation of a biconcave Worst-Fechner lens into a phakic eye effectively corrected high myopia with a stable refractive outcome, but 13.4% of implanted eyes suffered significant progressive reduction of endothelial cell density. This style lens is no longer in clinical use.

Adult↗

Correction of myopia by implantation of a concave Worst-iris claw lens into phakic eyes.

The Worst-Fechner Biconcave Lens for the correction of myopia in phakic eyes is fixated to the anterior iris. Of the 125 eyes implanted between November 1986 and November 1990, 109 eyes ("core group") had a follow-up period of at least 12 months (mean, 25.0; range, 13 to 51). Sixty-eight of these eyes were reexamined at Giessen University Eye Clinic by an independent investigator using a laser flare cell meter; 23 of the eyes also were examined by iris fluorescence angiography. Seventy-five of the 109 eyes (68.8%) were corrected within 1.00 diopters of the desired refraction, and only 10 eyes (9.2%) deviated more than 2.00 D from the calculated correction. The anatomical results were characterized by good fixation, absence of glaucoma, inflammation, and leak from iris vessels. However, the corneal endothelium was damaged in five eyes by surgical trauma, three resulting in corneal edema. In addition, in five eyes the endothelial density decreased during the follow-up period despite an uncomplicated operation, resulting in corneal edema in one eye. These eyes may have had anterior chambers that were too shallow.

Adolescent↗

Retarded corneoscleral wound healing associated with high preoperative doses of systemic steroids in glaucoma surgery.

We compared two groups of human eyes with corneoscleral wounds. One group consisted of 100 phakic myopic eyes which received an iris fixated "claw" intraocular lens with a minus power optic. Prior to the operation, 350 mg of prednisone was administered systemically. Ten of these eyes (10%) developed a wound dehiscence requiring resuturing. The other group consisted of 1002 cataract operations where 20 mg of prednisone was administered subconjunctivally after the operation. No wound dehiscences occurred in this group. Pretreatment may be of value where fistual formation is desired, ie, with glaucoma surgery.

Cataract Extraction↗