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Biomedical subjects

P V Vasil'ev

Publications and source records attributed to P V Vasil'ev.

At least 19 recordsLinked to original sources
PubMed1999

[The effect of long-term hypokinesia on the course of pathological processes in animals].

Reported are results of studying the development of pathology in rats and rabbits. Immobilization was found to markedly influence super-heating, local inflammation, and fever. In superheated animals, rise in the rectal temperature in the experiment and control proceeded at a similar speed; however, recovery of temperature in the control rats progressed significantly slower due to, probably, the hyper-compensatory reaction of animals to the thermal exposure. Life span of the control animals following heat exposure amounted to 160 +/- 13 min with a 100% lethality, whereas in the experimental animals the lethality rate was essentially lower and they lived much longer before death. At all times symptoms of inflammation in the experimental animals were more distinct and complications on the background of immobilization were more frequent and severe; edema of tissues exceeded that in the control by 36.6-49.0%. Local hyperthermia also was greater by 1.1-1.4 degrees C compared with the control. Observed was higher frequency of secondary infections and complications. According to the pathomorphological examinations, immobilization enhanced the alterative processes, inhibited formation of the demarcation area, suppressed melting of necrotic masses and engendered other signs of more serious pathology. Analysis of the course of pyrogenous fever evidenced shortening of the T upward phase and extension of the post-peak fever as an effect of long-term immobilization.

Acute Disease↗
PubMed1993

[Pharmacological agents for the correction of the processes of work capacity rehabilitation in flight personnel].

Pharmacological correction of performance capability of rehabilitation processes in flight crews depends on the character and intensity of sustained loads under the influence of flight and corresponding changes of energoplastical synthesis in human organism. The authors make a proposal to influence upon the processes of energoproducts not only after the work (postlabour rehabilitation), and immediately in the process of work (current rehabilitation), but also before the flight activities (preventive rehabilitation). The article contains the results of administration of bemitil, panangin, asaparal, acephen, fenibut, natrium oxibutirate and ascorbic acid. There are recommendations for aviation physicians concerning the usage of these medications for performance capability correction of the flight crews.

Aerospace Medicine↗
PubMedDate not supplied

[Psychopharmacology in aviation and astronautics].

Flights aboard modern vehicles are associated with high nervous-emotional and physical stresses. This may induce depletion of reserve capabilities, development of fatigue and, consequently, reduction of work capacity of crewmembers. The paper discusses approaches and results of the use of drugs by pilots and cosmonauts in order to alleviate their fatigue and emotional stress. It gives indications and contraindications for the adminstration of stimulants and tranquilizers. On the basis of a comprehensive analysis of the literature data and their own findings, the authors draw the conclusion that the use of stimulants and anxiolytics may increase the level of reliability and performance of air- and spacecraft pilots during programmed and, particularly, contigent situations of the flight.

Aerospace Medicine↗