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Biomedical subjects

P V Walsh

Publications and source records attributed to P V Walsh.

8 recordsLinked to original sources

Factors associated with mammographic parenchymal patterns.

The relationship between mammographic parenchymal patterns and known risk factors for breast cancer was studied in 5319 consecutive women presenting for breast screening. Using a multivariate analysis, correlations were found in pre-menopausal women between breast size, weight, age at first pregnancy, history of biopsy and history of cyclical breast pain and parenchymal pattern. In post-menopausal women the parenchymal pattern correlates with breast size, weight, weight change, age at first pregnancy, a history of biopsy and a history of breast feeding. The DY pattern correlated with age, breast size, weight, history of biopsy and menopausal status. When pre-menopausal women were considered separately the DY pattern correlated only with weight and breast size.

Age Factors↗

Cyclical mastalgia: clinical and mammographic observations in a screened population.

The incidence of cyclical mastalgia in well women presenting for breast screening was 69 per cent. The incidence of cyclical mastalgia increases with age up to the menopause. There was a higher incidence of 'high risk' mammographic patterns and a lower incidence of 'low risk' patterns, according to the Wolfe classification, in women with cyclical mastalgia compared with the rest of the screened population. This finding correlated with the severity, duration and need for treatment. The differences in breast pattern did not persist after the menopause. The question of whether or not cyclical mastalgia can be regarded as a risk factor for breast cancer is uncertain and needs further evaluation.

Adult↗

Colectomy for slow transit constipation.

A series of 21 patients (18 female) whose intractable constipation was treated by colectomy between 1976 and 1985 is reported. There was no mortality attributable to surgery in this series. Total colectomy with ileorectal anastomosis was the preferred operation, but it produced a satisfactory result in only 12 patients. Five patients were treated by a permanent ileostomy, as the primary procedure in two. Megarectum did not automatically preclude a good result from ileorectal anastomosis, but a poor result was associated with failure of either a rectal stump to conduct colonic movements or of the anal sphincter to relax. Long term follow-up is necessary for assessment of results since late relapse can occur.

Chronic Disease↗

Serum oestradiol-17 beta and prolactin concentrations during the luteal phase in women with benign breast disease.

Serum profiles of both oestradiol and prolactin were measured during the luteal phase in normal women, in women with cyclical breast pain and in women with recently biopsied benign breast disease. The results suggest that, in women with benign breast disease, the concentration of both hormones may be increased, when compared to the normal controls, during the evening in the latter part of the luteal phase.

Adult↗

Rupture of the abdominal oesophagus: a review.

'Spontaneous' rupture of the oesophagus usually affects the lower third, less commonly the middle third and rarely the cervical oesophagus. Rupture limited to the intra-abdominal oesophagus is rare. Such a case is described here and previously reported cases are reviewed. Vomiting-induced gastro-oesophageal injuries and their aetiology are discussed and the management of spontaneous rupture is reviewed.

Abdomen↗