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P Valentini

Publications and source records attributed to P Valentini.

82 records · Page 5Linked to original sources

[Serological recognition of agglutinins against O and H antigens of various Salmonellae in "normal" adult subjects].

The distribution of Salmonella agglutinins among 390 normal sera from people living in the district of Pisa is described, and the relation of these findings with the Salmonella serotypes occurring in the same area is discussed. Clusters of agglutinins for several O and H antigens were found at or above a titre of 1:20, in many samples. In order to explain the significance of such antibodies and their origin an identical survey was carried out on some sera from patients with chronic liver disease, using the same antigens suspensions. The results from healthy persons compared with the increased antibody titres detected in liver patients support the hypothesis that the anti-Salmonella agglutinins may be originate by various antigenic stimuli which may be specific or most frequently non-specific, since it is well established the cross-reactivity between both the somatic and flagellar antigens of Salmonella and those of other organisms.

Adult↗

[Clinical-instrumental dissociation in a case of Reye's syndrome].

We report the case of a boy 5 years old we admitted to our PICU with signs of impending hepatic failure (hypertransaminasemia, hyperammonemia, prolonged PT) following mild upper respiratory infection and irrepressible vomiting. We observed no neurological abnormalities excepting slight lethargy; on the contrary, EEG findings showed severe diffuse slowing and high-voltage Delta activity. Our diagnosis of Reye's syndrome was later confirmed by liver biopsy. Clinical and electrophysiological signs recovered after 48-72 hours and no explication was found for this anomalous Reye's syndrome presentation. Further studies are needed for understanding the basis of neurological involvement of stage I Reye's syndrome.

Biopsy↗