PubMed Health⌕ Search

Biomedical subjects

P Veerraju

Publications and source records attributed to P Veerraju.

At least 19 recordsLinked to original sources
PubMed2000

Plasma protein polymorphisms in Paidies and Valmikies of coastal Andhra Pradesh, south India.

Five plasma protein polymorphisms--Haptoglobin (HP), Group Specific Component (GC), Transferrin (TF), Albumin (ALB) and Caeruloplasmin (CP)--have been determined in two endogamous populations (Paidies and Valmikies) of North Coastal Andhra Pradesh, South India. The results were compared between the two populations. They revealed significant differences for the TF system only. The results were also compared with those available from other Andhra Pradesh populations.

Blood Proteins↗
PubMed1999

Some atypical and rare sickle cell gene haplotypes in populations of Andhra Pradesh, India.

We have investigated the clinical, hematological, and molecular genetic characteristics of sickle cell anemia patients from 6 populations of Andhra Pradesh, South India. Of 72 sickle cell chromosomes (HBB*S) 60 belong to characteristic Arab-Indian haplotypes, 6 to variant Arab-Indian haplotypes, 1 to a Bantu haplotype, 2 to a Cameroon haplotype, and 3 to rare haplotypes. This is the first report of a Bantu haplotype in an Indian population. Some information on haplotype characteristics of normal chromosomes (HBB*A) is also presented. The average hemoglobin level was 7.3 g% and mean fetal hemoglobin (HbF) level was 12.6%. The higher HbF levels corroborate earlier observations in sickle cell homozygotes from India. Clinical investigations have revealed splenomegaly and painful crises as the most common features in these patients.

Adolescent↗
PubMed1997

Sickle cell haemoglobin and glucose-6-phosphate dehydrogenase deficiency among Rellis of Visakhapatnam, Andhra Pradesh, South India.

Sickle cell haemoglobin and glucose-6-phosphate dehydrogenase deficiency have been investigated in two endogamous subgroups of the Rellis, a scheduled caste population of Visakhapatnam of Andhra Pradesh (South India). The frequency for the sickle cell gene is higher among Relli-I (0.1216) than in Relli-II (0.0454). The incidence of G-6-PD deficiency is higher among Relli-II (0.0454) than in Relli-I (0.0328). The results were also compared with those available from other Andhra Pradesh populations.

Female↗
PubMed1996

A report on an extremely rare superoxide dismutase phenotype from India.

This paper reports an extremely rare variant phenotype of Superoxide Dismutase (SODA 2) in a female individual belonging to the Shia Muslim population of Vizianagaram, Andhra Pradesh, South India whose parents are not consanguineous. This is the third report in the world so far. The corresponding SODA phenotype of other family members of the proposita were also investigated. The results and their significance are discussed in the light of earlier works in India and world populations.

Adult↗
PubMed1996

Plasma protein polymorphisms in two Viswa populations of Coastal Andhra Pradesh (south India).

Group specific component (GC), Haptoglobin (HP), Transferrin (TF), Caeruloplasmin (CP) and Albumin (Alb) plasma protein genes were studied in two endogamous Viswa subpopulations, the Viswa Brahmin caste and an artisan community (goldsmiths and carpenters) from Visakhapatnam (Coastal Andhra Pradesh, South India). No significant differences were found between the two subpopulations. The results were also compared with those available for other Andhra populations.

Alleles↗
PubMed1992

Plasma protein polymorphisms in Malas and Madigas of coastal Andhra Pradesh, south India.

Four plasma protein polymorphisms: Group specific Component (GC), Haptoglobin (HP), Transferrin (TF) and Caeruloplasmin (CP), have been determined in two endogamous populations (Mala and Madiga) of Visakhapatnam of Coastal Andhra Pradesh, South India. The results were compared between the two caste populations and they revealed no significant differences. The results were also compared with those available from other Andhra populations.

Blood Proteins↗
PubMed1988

A genetic study of the Konda Kapu tribe of coastal Andhra Pradesh, South India.

Phenotype and gene frequencies of two blood group and four red cell enzyme systems were examined in a Konda Kapu tribal sample of Coastal Andhra Pradesh, South India. The gene frequencies for these systems in Konda Kapus indicate the middle range values for Andhra Pradesh tribal populations, excepting the ADA and Rh(D) systems, where extreme range values are found. Further, gene flow is indicated between the Konda Kapus under study and Plain Kapus, a neighbouring caste population by calculation of Fi estimates.

ABO Blood-Group System↗
PubMed1984

Gc subtyping in south Indian tribal and caste populations.

Seven tribal (Konda Kammara - 2 samples; Koya Dora - 3 samples; Lambadi) and caste (Madiga) populations from Andhra Pradesh (South India) have been analyzed for the distribution of Gc subtypes. The observed heterogeneity in the distribution of Gc1F, Gc1S and Gc2 alleles was found to be statistically significant. Comparisons are made with North Indian populations as well as with those of other racial affiliation. The anthropological impact of the Gc subtype polymorphism is discussed.

Alleles↗
PubMed1983

Acid phosphatase among Brahmin and Kamma caste populations of coastal Andhra Pradesh, India.

Haemolysate samples from two caste populations, namely Brahmin and Kamma from coastal Andhra Pradesh, India, were typed for acid phosphatase by using starch gel electrophoresis with the discontinuous buffer system. The sample includes 225 Brahmins and 221 Kammas. Only A, B and AB phenotypes were observed and a statistically significant difference was found between the two caste groups in their acid phosphatase distribution. An association of higher B gene frequency with non-vegetarian diet is also suggested.

Acid Phosphatase↗
PubMed1982

Blood groups among Brahmin and Kamma caste populations of Coastal Andhra Pradesh.

Blood specimens from Brahmin and Kamma caste populations of Coastal Andhra Pradesh, India are examined for A1A2BO, MNSs, and Rhesus blood groups. Predominance of A group in Brahmins and B group in Kammas is observed. Phenotype A2 records less than 4% in both populations. High frequencies of genes M, s, D, and e are exhibited among both populations. Statistically significant differences are found only for A1A2BO system between Brahmins and Kammas.

ABO Blood-Group System↗
PubMed1982

Genetic studies on the Koya Dora and Konda Kammara tribes of Andhra Pradesh, India.

A total of 209 persons belonging to the Koya Dora and Konda Kammara tribes in the East Godavari District of Andhra Pradesh, have been tested for electrophoretic variation in 9 red cell enzyme systems. The gene frequencies for the systems showing variation are, in general, within the range for other Andhra Pradesh tribal populations. There is 1 example of PHI 2-1 in the Konda Kammara, while 1 case each of PHI 3-1 and 2-1 are reported in the Koya Dora. In PGM1, there is one example of the 6-2 phenotype and one of 4-1 in the Koya Dora. The Koya Dora show a relatively lower frequency of the EsD2 allele compared to the Konda Kammara. The gene frequencies for the GLO system are reported here for the first time among Indian tribals and these are within the Indian range. LDH Calcutta 1 was not detected in either population.

Acid Phosphatase↗
PubMed1982

Blood groups and ABH saliva secretion in Koya Dora and Konda Kammara tribes of Andhra Pradesh.

The present paper reports the distribution of blood groups and ABH saliva secretion in two Andhra tribal populations: the Koya Dora and the Konda Kammara. 100 Koya Dora and nearly 110 Konda Kammara adults of both sexes were tested for A1A2BO, MN, Rh (CcDEe) blood groups and ABH saliva secretion. The gene frequencies for A1A2BO, MN and ABH and the gene as well as chromosome frequencies for Rh (CcDEe) systems were calculated. Koya Doras show a higher incidence of A gene than B gene, while the reverse trend is seen in Konda Kammaras. Both the tribes show a high M gene frequency. No Rh(D) negative individual was found in Koya Doras, while 4.59% of Konda Kammaras are Rh(D) negative. The chromosomes CDE, CdE, cDe, cdE, Cde and cde are absent in Koya Doras, while only the four chromosomes CDE, CdE, cDe and cdE are absent in Konda Kammaras. The chromosome CDe shows the highest frequency in both the tribes. The frequency of secretors is, as usual, higher than that of nonsecretors in both the tribes. The intergroup variation between the two tribes is not statistically significant for MN, Rh (CcDEe) and ABH systems, while the difference is significant for the A1A2BO blood groups. Suitable comparisons have also been made with all the other available data from Andhra Pradesh tribal populations with respect to different systems studied. Finally Fi estimates have been calculated after Harpending et al. (1973) and Workman et al. (1974) for Koya Doras and Konda Kammaras to assess their degree of endogamy, considering the codominant systems studied, which suggest that Koya Doras are relatively more isolated than Konda Kammaras.

ABO Blood-Group System↗
PubMed1981

Transferrin subtypes in six Indian population samples.

Transferrin subtypings have been performed on three population samples originating from Himachal Pradesh, North India (Pangwala, Gaddi-Bharmour valley, Gaddi-Kangra district) and on three samples from Andhra Pradesh, South India (Koya, Konda Kammara, Lambadi). Among these six populations, marked differences in the distribution of Tf phenotype and allele frequencies are present. All Indian samples differ clearly from the hitherto reported TfC1 and TfC2 allele frequencies. In one of our Indian samples, the Pangwala, the most likely existence of a new Tf subtype variant (Tf Pangwala) could be demonstrated.

Alleles↗
PubMed1981

Distribution of ABO and Rh (D) blood groups among the Konda Kammaras of Andhra Pradesh.

The frequency distribution of ABO and Rh (D) blood groups among the Konda Kammaras, a tribal population of Andhra Pradesh has been presented. In the ABO system (n = 125) the adjusted frequencies were: p = 0.2202, q = 0.1802 and r = 0.5996. The gene frequency (n = 123) of the Rh (D) negative trait was 0.2017. The results are compared with those from the neighbouring tribal and caste populations.

ABO Blood-Group System↗
PubMed1981

Beta 2-glycoprotein I--a Bi-Allelic polymorphism.

Population samples from Hungary and India have been typed for beta 2-glycoprotein I concentrations. Whereas the Hungarian sample is in fairly good accord with the genetic model set up by Cleve2-beta 2-glycoprotein I concentrations are controlled by two autosomal codominant alleles BgN and BgD-the Indian samples do not fit this model. Thus the Indian data favour the assumption of a more complex genetic mechanism controlling the serum concentration of this protein.

Adult↗