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Biomedical subjects

P Vergnes

Publications and source records attributed to P Vergnes.

63 records · Page 4Linked to original sources

[Superior tibial epiphyseal osteochondroma with intra-articular development. Apropos of 2 cases in children].

Two cases of intra-articular development of an osteochondroma in the proximal epiphysis of the tibia are reported. The first case, a 3 year old boy, resulted in blocking of the knee. After resection of the mass the diagnosis was confirmed by pathology. The second patient, an 8 year old boy, had no symptoms and surgery was not performed, although ablation was required of an associated astragalian osteochondroma of tibiotarsal intra-articular development. Relations between these epiphyseal osteochondromata and hemimelic epiphyseal dysplasia and metachondromatosis are discussed.

Bone Neoplasms↗

[Glandular and penile hypospadias. Elements of the abnormality. Therapeutic implications and results. From a study of 135 protocols].

Glandular, coronal or penile hypospadias is a more complicated disorder than at first sight appears. This article reviews 135 cases, and discusses the constituent elements-meatal ectopy, with or without meatal stenosis, ventral penile curvature, skin chordee and webbed or twisted penis. No urethroplasty was performed in twenty two boys with glandular or coronal meatus, the treatment being by circumcision or preputial plasty. Of the 113 patients undergoing urethral repair, 91 (80.5%) suffered from no complications in the postoperative course, but 22 (19.5%) developed complications. The most common was a urethrocutaneous fistula (16). Thirteen of these were successfully closed in an additional operation. Six patients developed meatal stenosis or urethral strictures (5.3%), and were treated by meatal dilatation (4), meatostomy (1) or endoscopic urethrotomy (1). The overall results of one-or two-stage urethroplasty, with or without further surgical treatment for fistula or stenosis, were good or very good in 96.5% of cases. We approve the present trend towards one-stage repair, using Mathieu's technique for distal penile hypospadias without penial curvature, Duckett's technique for all medial or proximal penial hypospadias, or for distal penial hypospadias with chordee, or MAGPI for glandular or coronal hypospadias. The best age for surgical treatment must be decided in the light of technical requirements, psychological stress factors and schooling. The authors advocate the performance of a single-stage operation at around three years of age, in order to limit the psychological stress arising not only from the disorder, but also from the need for hospitalization, which should therefore be kept down to the minimum.

Age Factors↗

Use of a long-acting somatostatin analogue (SMS 201-995) in controlling a significant ileal output in a 5-year-old child.

We report the efficacy of a long-acting somatostatin analogue, associated with conventional therapy, in controlling profuse ileostomy losses in a child with short bowel syndrome following a volvulus. The first therapeutic effects of the treatment [50 to 100 micrograms/day of SMS 201-995 (Sandoz Ltd.) subcutaneously] appeared 48 h after institution. Ileal output was reduced on an average from 1,800 to 600 ml. The transit time to the ileostomy was prolonged from 20 to 360 min. The loss of chloride and sodium was reduced. Clinical tolerance was good. This treatment allowed rapid weaning of parenteral nutrition and implementation of a constant rate enteral infusion with rapid nutritional restitution. Hospitalization was shortened and this treatment raises future opportunities in the short bowel syndrome.

Child, Preschool↗