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P Vesterager

Publications and source records attributed to P Vesterager.

4 recordsLinked to original sources
PubMed1993

Transcutaneous devices for the measurements of pO2 and pCO2. State-of-the-art, especially emphasizing a pCO2 sensor based on a solid-state glass pH sensor.

In treating critically ill neonates it is vital to ensure optimal delivery oxygen to the tissue and simultaneously make sure that carbon dioxide is removed from the tissue. The continuous non-invasive transcutaneous measurements of pO2 and pCO2 make it possible to detect sudden changes in pO2 and pCO2 immediately, so prompt corrective action can be implemented to ensure optimal neonatal patient care. A new combined solid state transcutaneous sensor for measurement of pO2 and pCO2 is described in the paper. The pO2 part of the sensor has been redesigned and its performance improved to ensure more reliable pO2 readings during in vivo measurements. The pCO2 part of the sensor has been completely redesigned. The application of a new solid state technology in the production of the pCO2 combined with the use of a new, reinforced, composite pH sensitive glass membrane, has resulted in an extremely robust and reliable pCO2 sensor.

Blood Gas Monitoring, Transcutaneous↗
PubMed1982

Effect of electrode temperatures on monitoring of transcutaneous carbon dioxide (TcPCO2) in prematures.

To establish the optimal electrode temperature for monitoring of transcutaneous PCO2 (TcPCO2) in neonates, a study was performed using electrode temperatures of 37, 42, and 44 degrees C, respectively. The tests were performed by means of TcPCO2 electrodes designed by Radiometer A/S, Copenhagen. In 22 neonates 22 paired values of TcPCO2 and arterial PCO2 (PaCO2) were obtained at each of the above-mentioned electrode temperatures. The correlation coefficient obtained at an electrode temperature of 37 degrees C was 0.83. At electrode temperatures of 42 and 44 degrees C the correlation coefficients were improved to 0.96 and 0.94, respectively, TcPCO2 always being higher than the simultaneously measured PaCO2. An enlarged study comprising 32 neonates at an electrode temperature of 42 degrees C showed the regression line between PaCO2 (mm Hg) and TcPCO2 (mm Hg) to be PaCO2 = 0.81 . TcPCO2 - 2.8.

Arteries↗
PubMed1977

Transcutaneous pO2 electrode.

Measurements of pO2 on the skin surface (tc-pO2) by means of a conventional Clark electrode have under normal conditions (i.e., without producing hyperaemia) shown low tc-pO2 values and thereby indicated only a small exchange of oxygen through the skin. By using a heated Clark electrode specially designed for application on the surface of the skin it is, however, possible to perform continuous, non-invasive monitoring of tc-pO2 which is highly correlated to the arterial pO2 (pO2 (aB)) and which responds rapidly to changes in the inspired oxygen concentration (pO2 (I)). The tc-pO2 electrode developed by Radiometer and based on the above mentioned principles, viz.: --the use of a Clark oxygen electrode --the application of hyperthermia to produce local hyperaemia is described together with the Radiometer TCM1 TC OXYGEN MONITOR. The in vitro calibration of the electrode is performed at 43 degrees C using water saturated with atmospheric air as high calibrating standard, and a sulphite solution as zero standard. The response time of the electrode lies within the range 12-18 sec for 95% response when using a 25 mu Teflon (FEP) membrane. If the calibration is performed as described, the electrode will respond almost linearly to pO2 values up to 700 mmHg.

Blood Gas Analysis↗