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Biomedical subjects

P W Cotter

Publications and source records attributed to P W Cotter.

5 recordsLinked to original sources
PubMed1986

Epidermoid cyst of the spleen.

Epidermoid cysts of the spleen are extremely rare, occurring mainly in people under 20 years of age. They are thought to originate from an abnormality in the development of the spleen during the seventh week of embryological life, when the spleen is close to the mesonephric tissues. Cysts present as an asymptomatic abdominal mass or with pain in the left upper quadrant and/or the left shoulder. In the past the recommended treatment has been splenectomy, but with the changing attitudes towards splenic surgery a more conservative approach is now employed. Drainage under radiographic guidance, deroofing with external drainage or simply deroofing with drainage into the peritoneal cavity are now more popular techniques (along with simple cystectomy). Complications are few, although those associated with deroofing and internal drainage are inadequately investigated.

Adult↗
PubMed1983

Conversion of choline to phosphatidylcholine in the isolated-ventilated-perfused neonatal rabbit lung.

The isolated-ventilated-perfused neonatal rabbit lung model was used to study pulse dosed 14C-choline incorporation into 14C-phosphatidylcholine (PC) and 14C-disaturated phosphatidylcholine (DSPC). 14C-PC and 14C-DSPC synthesis were linearly dependent upon perfusion time to 30 min and upon the pulse dose of 14C-choline of 20-250 nmol at both 10 and 30 min of perfusion. 2-3% of the pulse-dosed choline was taken up by the lung. The water-soluble metabolites of choline found in lung after 10-30 min of perfusion were: choline, 50-60%; betaine 2.4-3.0%; phosphorylcholine, 26-41%, and CDP-choline, trace-10%. 1-day-old perfused lungs incorporated pulse-dosed 14C-choline into 14C-PC and 14C-DSPC at slightly higher rates than at 10 days old. Newborn rabbits receiving an intraperitoneal injection of 0.1 mg dexamethasone/100 g body weight 16 and 22 h prior to perfusion incorporated significantly more 14C-choline into 14C-PC and 14C-DSPC than saline-injected controls.

Animals↗
PubMed1975

Christchurch traffic trauma survey: Part 2, victims and statistics.

The results of a survey carried out at Christchurch Hospital examining the problem of traffic trauma are described. The majority of casualties were in the 15-24 age group and motorcyclists were especially prominent. The type and severity of injuries is discussed for each role, e.g., driver, passenger etc. The availability and use of safety equipment (seat belts and crash helmets) by the victims who came to hospital is also detailed. Accidents were found to occur predominantly (88 percent) in urban areas and very close to the victim's home.

Accidents, Traffic↗
PubMed1975

Christchurch traffic trauma survey: Part 1, Blood alcohol analysis.

Some accurate information concerning the drivers involved in traffic accidents was obtained in a survey at Christchurch Hospital. Investigation of these drivers' occupations revealed that a significant proportion came from the semi-skilled and unskilled occupational groups. Alcohol is confirmed as an important factor in traffic accidents and a number of other characteristics of the drivers are described. The dangers of relying on officially-acquired statistics for research work are revealed.

Accidents, Traffic↗