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P W Mark

Publications and source records attributed to P W Mark.

3 recordsLinked to original sources

Analysis of intracranial pressure.

Methods for the acqusition and analysis of intracranial pressure (ICP) signals are reviewed from clinical and technical perspectives. The clinical importance of ICP monitoring is presented, and methods for ICP transduction are briefly discussed. These methods include intraventricular catheters, subarachnoid screws, epidural techniques, and the new fiberoptic ICP measurement systems. Approaches to the visual analysis of the ICP waveform are presented, with special emphasis on the relationship between the ICP waveform and the arterial blood pressure signal. Methods of computer-based ICP analysis are also reviewed, including histogram and "systems analysis" methods. Methods to predict ICP pressure rises and to estimate intracranial compliance are also discussed. Finally, ICP monitoring is reviewed from the point of view of patient outcome. It is concluded that advanced ICP waveform analysis methods warrant further clinical evaluation to demonstrate their clinical usefulness.

Humans↗

Reflex bradycardia during surgery.

Reflex bradycardia and sinus arrest may occur in a variety of surgical procedures, from neurosurgery to general abdominal, laparoscopic, ophthalmic and facial surgery and even procedures such as liver biopsies and electroconvulsive therapy. In most cases a vagally-mediated reflex has been implicated, although experimental support for this is often lacking. Drugs such as vecuronium, atracurium, halothane, fentanyl and succinylcholine may predispose to this reflex. Premedication with an anticholinergic is usually effective in preventing its occurrence.

Bradycardia↗