Biomedical subjects
Publications and source records attributed to P Zalewski.
The authors present the problem of endocrine function of some neoplasmatic tumors based on their own very rare case of the larynx apudoma. They pay attention to the value of some modern diagnostic methods including radioimmunological determination of the serum peptide hormone levels and some specific immunofluorescence assays with monoclonal antibodies.
A two cases Wegener's syndrome was described. The current knowledge concerning the role of neutrophils in pathogenesis of Wegener's syndrome is reviewed.
The aim of this work was comparative evaluation of the cervical nystagmus in cervical torsion test with the Nylen's positional nystagmus and their diagnostic value in correlation from anatomical state of cervical column. The authors examined 40 patients with degeneration of cervical spinal column and with normal radiograph of cervical spinal column. The obtained results showed that the cervical nystagmus in cervical torsion test was more frequent (47.5%) than the Nylen's positional nystagmus (37.5%). The cervical nystagmus in cervical torsion test was observed also in health subjects. The authors think that the above mentioned deviations can be caused by the discreet degeneration of cervical spinal column, unseizable in radiograph. The examinations showed that the cervical nystagmus in cervical torsion test could be used simultaneously with the Nylen's positional nystagmus in diagnostic of vertigo, first at all in patients with degeneration of cervical spinal column.
The authors discuss a problem of rarely occurring bifocal carcinomas with the presentation of their own case of laryngeal carcinoma and branchiogenic cyst of the neck. They pay attention to histopathologic features underlying the diagnosis of branchiogenic cyst carcinoma and to the necessity of oncologic alertness in tumors of these kinds.
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Function of the acoustic organ and the vestibular organ in correlation from radiograph of cervical spinal column was examined in 102 patients aged 20-68 years, of both sexes. The obtained results of audiometric and electronystagmographic investigations have shown that the greatest disorders of function of the acoustic organ and the vestibular organ was at the patients with osteophytes and discopathy in cervical spinal column. Impaired hearing and vestibular disorders was observed also at the patients with normal radiograph of cervical spinal column. The authors have thought that the above deviations can be caused by irritation even the discreet degeneration of cervical spinal column, which ones conduct to increased tension of sympathetic system.
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Sonometric and dosimetric measurements of noise at a dozen workplaces of three divisions in a refinery-petrochemical plant have been made. The equivalent level allowable with a view to hearing protection was found to be exceeded by 1-3 dBA at some workplaces. The tonal audiometric test was used to determine threshold levels for 250-8000 Hz frequencies in 122 workers. The present acoustic conditions at the test workplaces do not pose a risk of a significant hearing loss. Only a slight high-frequency hearing loss which might result from noise exposure was diagnosed. Not a single case of occupational hearing impairment conformable with the mandatory diagnostic and certificatory rules was reported.
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The authors have presented results of examinations of the smell and taste senses in 547 petrochemistry, workers, and 100 cotton industry workers composing a control group. In both groups, those aged 26 -- 35, with long duration of employment, predominated. In the primary group i.e. petroleum chemistry workers, dysgeusia has been found in 319 (58.3%) subjects with no reaction at all in 102 (18.6%) persons. Hyposmia has been found in 238 (43.5%) and anosmia in 50 (9.2%) subjects. In the control group, dysgeusia has been found in 69%, whereas anosmia in 24% of subjects.
The prevalence of occupational hearing impairment constantly increases, thus there are more and more people who become deaf and disabled from carrying on their jobs and normal social contacts. The technical efforts aimed at limiting exposure to noise, as well as medical prophylactic activities are not efficient enough. Therefore the authors analyse the possibilities of occupational hearing impairment treatment. Pharmacologic preparations likely to affect the temporary and permanent threshold shift, are considered. Within operative treatment, microsurgical technique of implanting microelectrodes to the cochlea is presented, basing on the authors' experiments with 4 patients op]erated and rehabilitated with this method.
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