Biomedical subjects

P Zeyen

Publications and source records attributed to P Zeyen.

4 recordsLinked to original sources

PubMed2006

Phthiriasis palpebrarum: 2 case reports.

Phthiriasis palpebrarum, caused by the phthirus pubis, is a rare cause of blepharoconjunctivitis, and is therefore often neglected. We present 2 patients who suffered itching and irritation at the right upper eyelid. Biomicroscopic examination showed a few lice and nits anchored to the eyelashes. Dermatologic examination revealed the presence of numerous lice and nits at the trunk and pubic area. The lice and nits were manually removed if possible, and the patients were asked to put vaseline on the eyelid margins. The patients were also treated with malathion 0.5% lotion. After control, two weeks later, no more lice nor nits were present in the first patient.

Adult↗

PubMed1999

The long-term effect of Yag laser posterior capsulotomy on intraocular pressure after combined glaucoma and cataract surgery.

In order to evaluate the long-term effect of Yag laser posterior capsulotomy on intraocular pressure (IOP) after combined cataract and glaucoma surgery, we retrospectively studied 20 patients who underwent posterior capsulotomy after single-site combined phacoemulsification and trabeculectomy. We assessed mean IOP and number of glaucoma medications. The mean follow-up was 3 months (range 1 to 6 months). Mean IOP's remained almost unchanged, and were 13.9 +/- 2.7 before and 14.8 +/- 3 mmHg after capsulotomy (p = 0.115). The mean number of medications (0.4) remained unchanged. We conclude that Yag laser posterior capsulotomy does not significantly affect bleb function or glaucoma medication use in patients who underwent combined phacoemulsification and trabeculectomy.

Aged↗

PubMed1999

Comparison of the effect of Healon vs. Viscoat on endothelial cell count after phacoemulsification and posterior chamber lens implantation.

To evaluate the protective effect of 1% sodium hyaluronate (Healon) vs. a mixture of 4% chondroitin sulfate and 3% sodium hyaluronate (Viscoat) on the central corneal endothelium during surgery, we prospectively examined 20 eyes of 20 patients who underwent clear corneal phacoemulsification and implantation of an intracapsular posterior chamber intraocular lens (PC-IOL) with either Healon (10 eyes) or a combined use of Viscoat and Healon (10 eyes) as viscoelastic material. We compared the central endothelial cell counts, recorded by specular microscopy, preoperatively and 6 weeks postoperatively. Our results suggest that Viscoat offers no significant better endothelial cell protection during phacoemulsification than Healon.

Adult↗

PubMed1987

Attenuation of the virulence of the M strain of Plasmodium cynomolgi during prolonged multiplication in splenectomized rhesus monkeys.

The primary data in this report showed that prolonged multiplication of the M strain of Plasmodium cynomolgi in splenectomized rhesus monkeys led frequently to emergence of parasites whose virulence for monkeys with intact spleens was markedly attenuated while that for splenectomized monkeys was unimpaired. Expressions of attenuation regularly included reductions in the height of the peak parasitemia and in some instances failure to induce infection with inocula 1,000-fold those infective for splenectomized monkeys. Attenuation of virulence, once established, was maintained through as many as 17 serial passages in intact monkeys and more than 100 such transfers in splenectomized monkeys. Not only asexual blood stages, but also sexual stages (gametocytes) carried the attenuated characteristic, as indicated by its ready passage through mosquitoes. Studies in monkeys with sporozoite-induced infections showed that the persisting exoerythrocytic stages did not participate in the attenuation phenomenon; for when erythrocytic parasites of reduced virulence were cleared from the blood by either immune processes or chemotherapy, they were replaced upon relapse with parasites of unimpaired virulence. A major effort to determine whether splenectomized monkeys carried plasma or erythrocyte factors responsible for displays of attenuated virulence was nonproductive. An intact spleen was the essential element in these displays, for they disappeared immediately upon removal of this organ. The attenuation phenomenon probably reflects selection of spontaneously occurring mutants with limited capacity to escape normal splenic clearance mechanisms and unimpaired or even enhanced capacity to multiply in splenectomized monkeys.

Animals↗