[Epidemiologic considerations on the significance of benzodiazepine combined with alcohol in traffic].
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Biomedical subjects
Publications and source records attributed to P Zink.
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Toxicological analyses of blood and/or urine specimens collected between 1980 and 1981 revealed that 34.7% of all traffic accident victims (n = 144) had measurable concentrations of drugs. Analyses of blood samples taken from traffic offenders (n = 250) in 1979, on the other hand, showed 22.4% to have consumed drugs with or without alcohol. This percentage is comparable with values reported in other studies. Our results indicate that the widespread use of drugs represents a hazard for traffic safety in Switzerland. Road safety is additionally jeopardized by the often concomitant consumption of alcohol.
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Morphological changes in the skin of animals were studied after application of concentrated hydrofluoric and hexafluorosilicic acid. The intact skin was not generally affected by these acids. Areas injured before application of the acid showed, however, a continuous spreading of necrosis in the deeper regions. The first histological changes were noticed 1 h after the application. Such early histological findings could be seen long before any macroscopic reaction. The main characteristic findings were the hypocellular necrosis and edema reaching as far as the subcutis. The necrosis showed sharp leukocyte demarcations.
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In central European countries phosphorus poisonings are rare today. A case of a suicidal intoxication with yellow phosphorus was studied. The clinical course showed the typical three stages including a symptom-free period, although death occurred within 50 h from acute toxic damage of the myocardium. The oral ingestion of phosphorus presents an emergency which demands immediate treatment. Prognosis is depending on the amount of phosphorus absorption in the intestine which is expected to be high if the poison is in a liquid vehicle.
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