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Biomedical subjects

P de la Oliva

Publications and source records attributed to P de la Oliva.

8 recordsLinked to original sources
PubMed1989

Dosage of nifedipine in hypertensive crises of infants and children.

Eight hypertensive crises (HC) were treated with 2.5 mg of sublingual nifedipine in three children with weights below 10 kg (group A); 16 HC in 6 children between 10 and 20 kg with 5 mg (group B); and 40 HC in 10 children over 20 kg with 10 mg of nifedipine (group C). The relative decrease in both systolic and diastolic blood pressure was similar in all groups. The decrease was more rapid in groups A and B when the contents were extracted from the capsule and given directly. The hypotensive effect lasted 4 h. There were no side effects. The effective and safe single dose of nifedipine has been established to be 2.5 mg for children weighing less than 10 kg, and 5 mg for children weighing between 10 and 20 kg.

Acute Disease↗
PubMed1988

[Isoimmune neonatal neutropenia: apropos of a case].

Etiological diagnosis is a very important aspect in neonatal neutropenias because of different prognosis that implies. Isoimmune neonatal neutropenia is one of these processes, with good prognosis and which is rarely diagnosed; it is due to maternal isoimmunization during pregnancy against a foetus specific neutrophil antigen, inherited from the father. Authors present a case, in which a deep neutropenia during the first fifteen days of life, was observed with high monocytosis and without other associations; baby returned to normal levels when he was three months old. Presence of an antineutrophil antibody in mother's serum, with specificity against father's and baby's granulocytes was demonstrated. Bibliography is revised and differential diagnosis and treatment is discussed.

Agglutination Tests↗