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Biomedical subjects

Péter Riesz

Publications and source records attributed to Péter Riesz.

6 recordsLinked to original sources

[Experiences with radical cystectomy combined with urinary diversion by ureteral sigmapouch (Mainz-pouch II) in bladder cancer patients].

INTRODUCTION: The tumour of the bladder is the third most frequent urological malignancy. Muscle invasive cancer can be cured by radical cystectomy. After removing the bladder; a sufficient urinary diversion should be performed. AIM AND METHOD: The authors introduce the operative process of the pouch and their experiences with the procedure. The analysis of results were performed retrospectively. RESULTS: Between 1998 and 2005 the authors performed radical cystectomy in 76 patients followed by: Mainz pouch II urinary diversion. The average age of the patients was 59.8 (20-78) years. The distribution by gender was: 58 male, 18 female patients. The average pathological T stage was 2.3; 22 patients (29%) had metastatic lymph nodes. 94% of the cases were transitional cell cancers, 3 (4%) of them had adenocarcinoma and one leiomyosarcoma. Reoperation was carried out in 7 cases (9.2%) because of wound healing defects, and one patient was reoperated because of bleeding and ileus respectively. Transitionally nephrostomy was performed in 5 cases (6.5%) because of upper urinary tract dilatation due to a stricture of ureter anastomosis. The average survival period was 24.4 (1-98) months. CONCLUSION: Urinary diversion Mainz pouch II provides for safe, continent diversion requiring no urine bag; with an acceptable QL (quality of life). On the basis of the low number of complications and the acceptable QL; the authors consider this method as appropriate.

Adenocarcinoma↗

E-cadherin expression in transitional cell carcinomas.

The authors analyzed the expression of E-cadherin, one of the most important cell adhesion molecules, on histological slides of tumors of bladder cancer patients. The aim of the study was to see whether there is any association between E-cadherin expression and tumor grade, stage, age and gender of the patients, number of recurrences, or overall survival. The samples were examined in 51 primary bladder transitional cell carcinomas (TCC) of 50 patients, resected by transurethral resection (TUR) between January 1, 1996 and January 1, 1997. Immunoreactions were performed with monoclonal anti-human E-cadherin antibody. Forty of the fifty patients could be clinically followed. The analysis of the results on these forty patients was performed by contingency analysis and significance was assessed by chi2 test. No significant association between E-cadherin expression and tumor grade, stage, age or gender of the patients, the number of recurrences, or overall survival could be seen.

Adult↗

[Our results with radical retropubic prostatectomy in the first hundred patients].

INTRODUCTION: The most used treatment of localised prostate cancer is: retropubic radical prostatectomy. OBJECTIVE: The authors present their own results, on the basis of detailed discussions of 100 cases and compare them with international ones. METHODOLOGY: The authors analyse the data of 100 radically operated patients suffering of localised prostate cancer. The indication of the operations was based on the results of rectal digital examinations, serum PSA concentration levels and ultrasound guided, rectally performed, prostate biopsies. The average preoperative PSA level was 13.6 ng/ml; the mean age of the patients was 61.1 years. They analyse the early and late complications. They follow up the patients on a regular basis assessing the PSA level, continence and potency. RESULTS: The operation time, blood loss, amount of blood transfusion all decreased linearly during operations performed between 1998 and 2005. The longest period of follow up lasted for 70 months; the shortest lasted for 5 months. None of the patients died in the course of an operation or in 30 days following it; they lost one patient 18 months after the operation because of progression. From the late complications: in 22% of all cases they noticed anastomotic stricture constrictions which were resolved by urethrotomy. From all patients: 86% are fully continent; the rest mostly have grade 1 incontinence (requiring 1 pad per day). Altogether 18% of all patients have retained their potency without the use of drugs or appliances. CONCLUSIONS: The results are comparable to international data and are in harmony with them. Therefore early recognition and radical surgery of prostate tumors would be advisable.

Aged↗

[Review of our experiences and results with renal cell cancer patients in the last five years].

PATIENTS AND METHODS: The authors have collected and processed data of 307 patients at Urological Department Semmelweis University, who were treated for renal tumour from June 1997 to December 2002. RESULTS: During this process on the basis of their work, they formed their opinion of the main steps of diagnostical, surgical and conservative therapeutical procedure with patients suffering from renal cell cancer. They established the fact that the data is parallel with retraceable international literature, therefore this work can be the starting-point of long term prospective studies. They call attention to the fact that 70% of the tumours were recognized without any symptoms, during examination indicated for other reasons, due to the widely spreading of ultrasound, computed tomography and other imaging techniques. CONCLUSION: The tumours are recognized and removed in earlier stages and it is to be hoped that it prolongs their life expectancy, and makes the quality of life of our patients much better.

Adult↗

Renal tumor causing haematuria and sepsis.

A 28 year old female patient developed hematuria in the 32th week of her pregnancy. She was given antibiotic treatment, since a urinary tract infection was suspected. After delivery symptoms of acute pyelonephritis, then sepsis developed, and conservative therapy had no effect. Ultrasound examination showed unusual renal destruction, so nephrectomy was performed. Surgical intervention revealed the presence of an advanced tumor of the kidney, while histological examination confirmed a Bellini duct carcinoma of the kidney.

Abscess↗

Bilateral renal cell carcinoma in a horseshoe kidney.

We report a case of bilateral renal cell carcinoma in a horseshoe kidney. To the best of our knowledge this is the second reported case in the international literature. We performed different radiological examinations preoperatively to identify of blood supply, because correct preoperative location of vessels is mandatory.

Carcinoma, Renal Cell↗