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Biomedical subjects

Pablo Coto

Publications and source records attributed to Pablo Coto.

3 recordsLinked to original sources

[Cutaneous semiology: a historical perspective of the evolution of basic terminology in Spain].

There are still numerous incompatibilities in the definitions of basic dermatological terms. In Spain, the problem is aggravated by the coexistence and conflict between two different semantic models, imported from other countries (France and the USA). These two models really have different "units": one model can be called "essentialist" and the other "nominalist". These models are not original to Spain; rather, each one shows the predominance or influence of an outside culture. Through a historical and evolutional study, we were able to verify that the origin of these semantic models goes back to Joseph Plenck and Robert Willan (essentialist model) and to Ferdinand Hebra (nominalist model), respectively. An analysis of these models from a historical perspective may help in understanding the origin of the current conflicts in the everyday use of Spanish dermatological semiology, and may therefore help resolve them.

Dermatology↗

[Scleromyxedema: ultrastructural study].

Scleromyxedema is a type of mucinosis that presents with some well defined clinical and histopathological characteristics. We describe the findings observed with transmission electron microscopy in a case that we recently studied. The patient was a 56-year-old female with a localized eruption of lichenoid papules on the face, upper trunk and limbs. It was accompanied by IgG lambda gammopathy. Optical microscopy showed the findings typical of scleromyxedema. Electron microscopy revealed the existence of a large number of fibroblasts with high activity levels in the synthesis and release of collagen fibers and a mucoid substance.

Female↗

[Acquired flat angiomas in the form of a port-wine stain].

The development of flat angiomas in the form of a "port-wine stain" is an infrequent event in adults. We describe two cases of acquired flat angioma in the form of a "port-wine stain", which began in the second decade of life and grew slowly and steadily until reaching a large size. In the first case, it affected the front and back of the trunk, and in the second patient, the neck and left shoulder. Histopathology showed ectatic vessels in the papillary and reticular dermis, with no proliferation of endothelial cells.

Adult↗