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Biomedical subjects

Pablo Robles

Publications and source records attributed to Pablo Robles.

8 recordsLinked to original sources
PubMed2006

Myocardial calcification and subendocardial fatty replacement of the left ventricle following myocardial infarction.

We report a 70 years old man with old myocardial infarction of the anteroseptal wall. He had an acute anterior myocardial infarction ten years ago and coronary angiography showed a total occlusion of the left middle anterior descending coronary artery. He underwent a multidetector cardiac computed tomography for rule out another coronary stenosis before the surgery of a postrenal aortic aneurysm. The unenhanced computed tomography image realized for the quantification of the coronary calcium reveals a low-attenuation curvilinear stripe consistent with subendocardial fat at the anterior ventricular wall and a curvilinear focal apical left ventricular calcification. In this case without a precontrast CT the subendocardial fat could have been misinterpreted , leading us to conclude that a hypoenhancement area (perfusion defect) secondary from the reduced delivery of contrast in the subendocardium was present. The presence of calcium in the myocardium can make not trustworthy the estimation of the size of the infarct and the presence or absence of viability in the same one especially when it is realized by means of magnetic resonance.

Aged↗
PubMed2005

Congenital complete atrioventricular block and preexcitation syndrome: a well-matched partner.

A patient who had been previously diagnosed with congenital complete atrioventricular block (CCAVB) twenty years ago developed atrioventricular (AV) conduction through an accessory pathway (AP). With enhanced sympathetic tone (exercise, isoproterenol), 1:1 conduction down the AP occurred. An electrophysiologic study confirmed a suprahissian AV block and the presence of an AP. The AP was located on the left side and posterior. The absence of retrograde conduction through the AP and also a long conduction time were demonstrated.

Adult↗
PubMed2004

Visceral leishmaniasis in immunocompromised patients with and without AIDS: a comparison of clinical features and prognosis.

Visceral leishmaniasis is basically a disease of healthy infants and adults. However, in the last decade an increasing number of cases of kala azar in immunocompromised patients have been reported with emphasis on atypical manifestations of the disease. During a period of 11 years, 20 immunocompromised patients with AIDS (12 patient), haematological neoplasia (3 patients), corticosteroid therapy (3 patients) or renal transplantation (2 patients) were studied by one or more of the authors. We did not find differences in the presentation of leishmaniasis between patient with or without AIDS and most patients had fever, enlargement of the liver and spleen, blood cytopenias and biochemical abnormalities. Serology was more frequently positive in HIV-negative than in HIV-positive patients (100% versus 63.6%; P=0.13). Bone marrow biopsy was diagnostic in 66% and 87% of patients with and without AIDS, respectively. Failure of anti-leishmanial therapy occurred in 6 of 19 patients treated (31.5%), and 3 patients with AIDS and another 3 without AIDS died during the first episode of leishmaniasis. Of 12 survivors, relapses occurred in five (41.6%). Only patients in whom immunosuppression was ameliorated by means of antiretroviral therapy or by reduction of corticosteroid and other immunosuppressive drugs did not relapse. Treatment of kala azar in immunocompromised host is in satisfactory and new drugs or strategies are urgently needed.

Adolescent↗