PubMed Health⌕ Search

Biomedical subjects

Pak Leung Ho

Publications and source records attributed to Pak Leung Ho.

3 recordsLinked to original sources
PubMed2006

Invasive pneumococcal disease burden in Hong Kong children.

In a retrospective, population-based study, we estimated the age-specific incidence of invasive pneumococcal disease in Hong Kong between 1995 and 2004. The incidence rates per 100,000 were 18.3 (95% confidence interval [CI], 13.9-23.3) for children aged <or=2 years, 15.6 (95% CI, 12.8-18.6) for children aged <or=5 years and 1 (95% CI, 0.52-1.7) for children aged 6-14 years. The findings indicate a significant disease burden.

Adolescent↗
PubMed2004

Serotype distribution and antimicrobial resistance patterns of nasopharyngeal and invasive Streptococcus pneumoniae isolates in Hong Kong children.

A study was conducted to determine the vaccine coverage of prevalent carriage and invasive pneumococci from children aged less than 6 years in Hong Kong. A total of 383 nasopharyngeal carriage isolates and 88 invasive isolates from diverse sources were serotyped and their antimicrobial susceptibilities determined. The most common carriage serotypes were the same as the invasive isolates (6B, 14, 19F and 23F), although the rank order of specific serotypes was different. Serotypes in the 7-valent conjugate pneumococcal vaccine (4, 6B, 9V, 14, 18C, 19F and 23F) accounted for 89.7 and 66.1% of the invasive and carriage isolates, respectively. The same seven serotypes comprised 87.5% invasive isolates and 82.8% carriage isolates with resistance to penicillin, erythromycin and/or cefotaxime.

Algorithms↗