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Biomedical subjects

Pamela T Johnson

Publications and source records attributed to Pamela T Johnson.

15 recordsLinked to original sources

Multidetector row CT of superior mesenteric artery syndrome.

GOALS: The purpose of this case series is to illustrate the diagnostic criteria of superior mesenteric artery syndrome (SMAS) using 16-slice multidetector row computed tomography (MDCT) angiography with multiplanar and 3-dimensional reconstructions. BACKGROUND: SMAS is a rare condition causing functional obstruction of the third portion of the duodenum. When suspected, diagnostic imaging can be performed with upper gastrointestinal, arteriography, or CT. STUDY: Four patients with clinical symptoms and correlative CT evidence of SMAS are described. Axial, multiplanar, and 3-dimensional rendered MDCT images were retrospectively reviewed by 1 investigator, who measured the aortomesenteric angle and aortomesenteric distance on a sagittal maximum intensity projection rendering, and compared these values with normal ranges described in the literature. RESULTS: In each patient, MDCT demonstrated gastric and proximal duodenal dilatation with abrupt narrowing of the third portion of the duodenum between the aorta and SMA. Sagittal maximum intensity projection images reliably demonstrated the decreased aortomesenteric angle (mean in subjects 13.5 degrees, normal range 28 to 65 degrees) and distance (mean in subjects 4.4 mm, normal range 10 to 34 mm) in all 4 patients. CONCLUSIONS: As opposed to traditional imaging modalities like upper gastrointestinal and mesenteric arteriography, which depict either the bowel or vasculature respectively, CT enables direct visualization of obstructed bowel owing to duodenal compression by the SMA. Multiplanar MDCT with 3-dimensional rendering provides sagittal reconstructions that can be used to confirm the CT criteria of decreased aortomesenteric angle and distance in SMAS.

Adolescent↗

MDCT for suspected pulmonary embolism: multi-institutional survey of 16-MDCT data acquisition protocols.

The purpose of this study was to determine the extent to which a consensus exists on multidetector row computed tomography (MDCT) protocol parameters for suspected pulmonary embolism (PE). In August of 2004, a questionnaire addressing a number of body MDCT protocols was mailed to 99 fellows of the Society of Computed Body Tomography, representing a total of 46 institutions. In May 2005, this was followed up with a second mailing. The survey requested details pertaining to protocols for the most advanced MDCT scanner in the department. The overall survey response rate of 37% (17/46) yielded 15 protocols for 16-MDCT imaging of suspected PE. This data was tabulated and revealed a consensus for the use of bolus tracking, rapid contrast infusion, caudo-cranial scanning, the narrowest detector row collimation, and thin (<2 mm) reconstruction sections. However, contrast infusion timing, contrast concentration, and implementation of radiation dose modulation were variable. This compilation of protocols reflects recently published studies advocating the use of narrow acquisition collimation and reconstruction sections for MDCT of suspected PE. Future studies are necessary to elucidate the optimal intravenous contrast infusion parameters and further assess the efficacy of reduced radiation dose protocols.

Consensus↗

Multidetector-row CT of the appendix in healthy adults.

The purpose of this study is to characterize the caliber of the normal appendix and the effect of luminal content on appendiceal diameter in adults using thin section intravenous (IV) contrast enhanced multidetector-row computed tomography (MDCT). A retrospective review was conducted using the MDCT datasets from 82 adults being screened as potential renal donors. The four-channel CT technique included IV contrast and 1-mm collimation. Arterial phase scans were reviewed by two radiologists blinded to surgical history, to evaluate the following parameters related to the appendix: quality of visualization, origin and course relative to the cecum, maximum cross-sectional diameter of the lumen and luminal contents at the point of measurement, appearance of the periappendiceal fat, and presence of any luminal calcification. Medical records were reviewed to determine which subjects had reported a previous appendectomy or to confirm the absence of symptoms in any subjects with findings suspicious for appendicitis. The appendix was visualized in 72 of the 77 subjects who did not report an appendectomy (94%). The mean diameter of the collapsed appendix was 5 mm (range: 3-7 mm) and the air-distended appendix, 7 mm (range: 4-10 mm). Sixteen to 17% of the collapsed appendices measured 7 mm in diameter. Minimal periappendiceal stranding was identified in 2/72 subjects (3%). Chart notes from within 24 h of the MDCT confirmed no signs or symptoms of appendicitis in cases that demonstrated any CT finding suspicious for appendicitis. In this healthy, adult population, the collapsed appendix measured up to 7 mm at MDCT. Air distention of the lumen results in a wider diameter, up to 10 mm.

Adult↗

Sixteen-slice CT with volumetric analysis of foot fractures.

Computed tomography (CT) imaging of the foot demands excellent resolution for the delineation of complex fractures and joint alignment after trauma. The quality of current multislice volumetric acquisition results in exceptional multiplanar and 3-D reconstructions, precluding the requirement for an additional acquisition in a second plane. This pictoral essay depicts fractures of various bones of the foot, with reference to recent investigative studies demonstrating the value of CT in the evaluation of foot fractures.

Adolescent↗

Internet-based medical education: use of an "expert-corner" for disseminating radiologic information and determining users' educational interests.

RATIONALE AND OBJECTIVES: A website dedicated to body computed tomography (CT) offers users the opportunity to submit any question to a national expert. The purpose of this study was to characterize inquiries submitted over a 1-year period. MATERIALS AND METHODS: A total of 408 questions posed by users between February 2003 and February 2004 were reviewed and categorized. Web tracking was conducted to evaluate the program utilization over a 3-year period. RESULTS: Of the questions submitted, those addressing data acquisition protocols and intravenous contrast administration comprised 55% (224/408). Web tracking demonstrated that the number of visits to this educational program has progressively increased since 2003. CONCLUSIONS: Users requesting information were most interested in the proper performance of CT data acquisition. An Internet-based expert corner is a promising channel to deliver experience based radiologic information.

Internet↗

IV contrast selection for MDCT: current thoughts and practice.

OBJECTIVE: The purpose of this article is to review studies evaluating how contrast concentration affects MDCT of the body and to report IV contrast infusion protocols from MDCT angiography and MDCT of abdominal tumors. CONCLUSION: Higher concentrations (350 mg I/mL or greater) may improve visualization of small abdominal arteries. However, preliminary data comparing 300 mg I/mL to higher concentrations for MDCT of hypervascular hepatocellular carcinoma and pancreatic cancer have shown that higher concentrations may not increase tumor conspicuity.

Angiography↗

Internet-based dissemination of educational audiocasts: a primer in podcasting--how to do it.

OBJECTIVE: "Podcasting" is a relatively new Internet-based broadcast technology with unique characteristics that may prove valuable in radiologic education. In this article, we describe the procedure for generating, distributing, and downloading a podcast. CONCLUSION: Podcast technology holds promise as an inexpensive method to rapidly and cost effectively disseminate educational Internet audio broadcasts ("audiocasts").

Education, Medical↗

Spiral CT following the Whipple procedure: distinguishing normal postoperative findings from complications.

Following a Whipple procedure for a patient with pancreatic cancer, postoperative imaging with CT is essential to exclude complications and to identify recurrence. Accurate interpretation of these examinations requires knowledge of the type of surgery performed and the normal appearance of the abdomen on CT following this complex surgery. The purpose of this pictorial essay is to illustrate the normal appearance of the bowel following a Whipple procedure as well as some of the complications.

Diagnosis, Differential↗

Multidetector-row computed tomography with three-dimensional volume rendering of pancreatic cancer: a complete preoperative staging tool using computed tomography angiography and volume-rendered cholangiopancreatography.

Volume rendering, a postprocessing computer algorithm that creates three-dimensional (3D) displays from computed tomography (CT) datasets, can create 3D cholangiographic images (volume-rendered cholangiopancreatography, or VRCP) from intravenous contrast-enhanced abdominal CT datasets without the use of a biliary contrast agent. This article illustrates the utility of VRCP in the setting of biliary obstruction due to pancreatic cancer. The 3D renderings of the intra- and extrahepatic biliary tree provide valuable information for planning biliary drainage, including the location and length of the obstruction as well as the relationship of intrahepatic ducts to liver metastases.

Adenocarcinoma↗

Hemodialysis fistula occlusion: demonstration with 64-slice CT angiography.

The speed and resolution of 64-slice CT have resulted in new applications for CT angiography (CTA) owing to rapid data acquisition during the arterial phase, improved visualization of small vessels, and lengthened anatomic coverage. Extremity CT angiography is one such region. This case report shows the utility of multislice CTA for the evaluation of hemodialysis graft dysfunction.

Adult↗

Multidetector computed tomography for suspected appendicitis: multi-institutional survey of 16-MDCT data acquisition protocols and review of pertinent literature.

PURPOSE: To determine acquisition protocol parameters currently used by different institutions for appendiceal multidetector computed tomography (MDCT). MATERIALS AND METHODS: A survey inquiring about multiple MDCT protocols was mailed to 99 fellows of the Society of Computed Body Tomography in August of 2004, with a second mailing sent in May 2005. A total of 46 institutions or hospitals are represented by these Society of Computed Body Tomography fellows. Details pertaining to protocols for the most advanced MDCT scanner in the department were requested. RESULTS: The overall survey response rate was 17 of 46 or 37%. Fifteen protocols using 16-MDCT for suspected appendicitis were collected and tabulated. Parameters that are similar across institutions include a nonfocused acquisition using oral and intravenous contrast. Detector configuration is even divided between submillimeter and greater than 1 mm, and the most common reconstruction section thickness is 5 mm. CONCLUSIONS: Contrast administration and anatomical coverage are quite consistent across this set of protocols. However, future appendiceal MDCT research will need to address the most efficacious detector row collimation, reconstruction section thickness and interval, and the diagnostic capacity of protocols implementing dose reduction measures.

Adolescent↗

Volume rendering versus maximum intensity projection in CT angiography: what works best, when, and why.

The introduction and widespread availability of 16-section multi-detector row computed tomographic (CT) technology and, more recently, 64-section scanners, has greatly advanced the role of CT angiography in clinical practice. CT angiography has become a key component of state-of-the-art imaging, with applications ranging from oncology (eg, staging of pancreatic or renal cancer) to classic vascular imaging (eg, evaluation of aortic aneurysms and renal artery stenoses) as well as newer techniques such as coronary artery imaging and peripheral runoff studies. With an average of 400-1000 images in each volume data set, three-dimensional postprocessing is crucial to volume visualization. Radiologists now have workstations that provide capabilities for evaluation of these data sets by using a range of software programs and processing tools. Although different systems have unique capabilities and functionality, all provide the options of volume rendering and maximum intensity projection for image display and analysis. These two postprocessing techniques have different advantages and disadvantages when used in clinical practice, and it is important that radiologists understand when and how each technique should be used.

Algorithms↗