Biomedical subjects

Paolo Cherubini

Publications and source records attributed to Paolo Cherubini.

10 recordsLinked to original sources

PubMed2006

Inference-driven attention in symbolic and perceptual tasks: biases toward expected and unexpected inputs.

The aims of this paper are (a) to gather support for the hypothesis that some basic mechanisms of attentional deployment (i.e., its high efficiency in dealing with expected and unexpected inputs) meet the requirements of the inferential system and have possibly evolved to support its functioning, and (b) to show that these orienting mechanisms function in very similar ways in two perceptual tasks and in a symbolic task. The general hypothesis and its predictions are sketched in the Introduction, after a discussion of current findings concerning visual attention and the generalities of the inferential system. In the empirical section, three experiments are presented where participants tracked visual trajectories (Experiments 1 and 3) or arithmetic series (Experiments 2 and 3), responding to the onset of a target event (e.g., to a specific number) and to the repetition of an event (e.g., to a number appearing twice consecutively). Target events could be anticipated when they were embedded in regular series/trajectories; they could be anticipated, with the anticipation later disconfirmed, when a regular series/trajectory was abruptly interrupted before the target event occurred; and they could not be anticipated when the series/trajectory was random. Repeated events could not be anticipated. Results show a very similar pattern of allocation in tracking visual trajectories and arithmetic series: Attention is focused on anticipated events; it is defocused and redistributed when an anticipation is not confirmed by ensuing events; however, performance decreases when dealing with random series/trajectory--that is, in the absence of anticipations. In our view, this is due to the fact that confirmed and disconfirmed anticipations are crucial events for "knowledge revision"--that is, the fine tuning of the inferential system to the environment; attentional mechanisms have developed so as to enhance detection of these events, possibly at all levels of inferential processing.

Adult↗

PubMed2005

Generation of hypotheses in Wason's 2-4-6 task: an information theory approach.

We explored the "context of discovery" in Wason's 2-4-6 task, focusing on how the first hypothesis is generated. According to Oaksford and Chater (1994a) people generate hypotheses extracting "common features", or regularities, from the available triples, but their model does not explain why some regularities contribute to the hypothesis more than do other regularities. Our conjecture is that some regularities contribute to the hypothesis more than do other regularities because people estimate the amount of information in the perceived regularities and try to preserve as much information as possible in their initial hypotheses. Experiment 1, which used two initial triples, showed that the presence of high-information relational regularities in the initial triples affected the information in the initial hypotheses more than did the presence of low-information object regularities. Experiment 2 extended the results to the classic situation in which only one initial triple is given. It also suggested that amount of information is the only aspect of the structure of the triple that affects hypotheses generation. Experiment 3 confirmed the latter finding: Although relations are commonly distinguished between first-order and higher order relations, the latter being most important for generating hypotheses (Gentner, 1983), higher order relations do have an effect on Wason's 2-4-6 task only if their presence incre ases information. In the conclusion we discuss the statistical soundness of human hypotheses generation processes, and we ask an unanswered question: Amount of information explains why some regularities are preferred to others, but only within a set of "nonarbitrary" regularities; there are object regularities that are rich in information content, but are considered "arbitrary", and are not used in generating hypotheses. Which formal property can distinguish between these two sets of regularities?

Adult↗

PubMed2004

From models to rules: mechanization of reasoning as a way to cope with cognitive overloading in combinatorial problems.

It is hypothesized that the transition from unfamiliar problems to familiar, well-learned problems coincides with the transition from a model-based style of reasoning to a rule-based style of reasoning; model-based style of reasoning helps understanding the problem structure, but can overload working memory when the number of models required increases; rule-based style of reasoning avoids cognitive overloading, at the cost of making individuals liable to mechanization errors. In Experiment 1, the number of models required to respond to a verification task affected response latencies with unfamiliar problems, but not with familiar problems, supporting the initial hypothesis. In Experiment 2, participants were prone to mechanization errors when confronted with slightly modified problems in the late stages of the experiment, supporting the hypothesis that they had developed a reasoning rule in the early stages and were blindly applying it. The findings suggest that model-based reasoning and rule-based reasoning serve different purposes and have different costs and benefits, are both available to human reasoners, and familiarization with a problem may induce the transition from the former to the latter. The findings also suggest that mechanization of reasoning may be the first step along a gradient of decreasing cognitive load, whose end-point is automatization, as discussed in theories of automatization of information processing.

Adaptation, Psychological↗

PubMed2004

The effect of outcome information on doctors' evaluations of their own diagnostic decisions.

BACKGROUND: Outcome bias is a psychological tendency to use outcome information in order to evaluate the quality of a previous decision, where decisions with bad outcomes are undervalued and decisions with good outcomes are overvalued. In some circumstances, being affected by outcome when evaluating a diagnostic decision might have important educational consequences: bad diagnostic decisions resulting, by chance, in good outcomes might be repeated in the future, whilst good diagnostic decisions with bad outcomes might be abandoned. However, no previous studies have tested whether outcome bias affects doctors' evaluations of their own diagnostic decisions. METHODS: A total of 91 practising Italian doctors (69 general practitioners, 22 neurologists) chose a diagnosis for a neurological case and then evaluated it after receiving outcome information (positive outcome, adverse outcome or no outcome). RESULTS: Outcome information affected the doctors in many ways: the quality of the decision was overrated following good outcomes, and underrated following bad outcomes; the difficulty of making the diagnosis was underrated after good outcomes and overrated after bad outcomes, and the memory of weightings assigned to signs and symptoms consistent with the diagnosis was overrated after good outcomes and underrated after bad outcomes (and vice versa for the weighting of evidences inconsistent with the diagnosis). CONCLUSIONS: Outcome bias in medical decisions is discussed in terms of its possible adverse effects on doctors' learning and knowledge revision processes: although sensitivity to outcomes may be desirable in some circumstances, in other circumstances it can cause either the fixing of incorrect knowledge or the improper revision of correct knowledge.

Adult↗

PubMed2003

Rethinking the focusing effect in decision-making.

According to Legrenzi et al. [Cognition 49 (1993) 37], in making a choice people consider only the alternatives explicitly represented in their mental model of the decision situation. Their idea has found empirical support in the "focusing effect": Individuals focus on the alternatives explicitly stated in the problem context, and do not take into account other possibilities. In their original study, Legrenzi and colleagues considered only one factor to account for the explicit representation of an alternative--i.e., its explicit verbal formulation in the decision problem. Recent theories of relevance and information gain can help articulate their original idea, suggesting that individuals explicitly represent relevant alternatives, whether or not they are explicitly formulated in the decision problem. In three experiments we first replicated Legrenzi et al.'s original experiment, and then showed that the explicit verbal mention of an alternative is neither sufficient nor necessary to focus on it. The results suggest that individuals are able to consider relevant alternatives, even when they are not made explicit in the verbal formulation of a decision problem.

Adult↗

PubMed2003

Long-term decrease in subjective perceived efficacy of immunosuppressive treatment after heart transplantation.

BACKGROUND: Mild, long-term non-compliance with immunosuppressive treatment after organ transplantation is common, and can result in early mortality. One possible source of non-compliance is the belief that the treatment is ineffective or unnecessary. This study investigates patients perception of the efficacy of their immunosuppressive treatment in a sample of heart transplant patients. METHODS: A questionnaire was given to 67 heart transplant recipients. The first part of the questionnaire addressed health-related behavior and attitude toward the immunosuppressive medication, using self-report questions. In the second part of the questionnaire, participants evaluated the perceived risk of rejection associated with non-compliant behaviors described in 8 scenarios. RESULTS: The data from the self-report questions showed a mild level of behavioral non-compliance, increasing over time, and a mild level of medication non-compliance. One third of the medication non-compliant patients chose the inefficacy or non-necessity of the treatment as a main cause of non-compliance. The second part of the questionnaire showed that subjective perceived efficacy of the immunosuppressive treatment decreased over time. CONCLUSIONS: Medication non-compliance is fostered by many factors. One of these is the belief that the treatment is ineffective or unnecessary. This belief increases over time, and could be the result of a non-clinical selective-attention bias.

Female↗

PubMed2003

Identification, measurement and interpretation of tree rings in woody species from mediterranean climates.

We review the literature dealing with mediterranean climate, vegetation, phenology and ecophysiology relevant to the understanding of tree-ring formation in mediterranean regions. Tree rings have been used extensively in temperate regions to reconstruct responses of forests to past environmental changes. In mediterranean regions, studies of tree rings are scarce, despite their potential for understanding and predicting the effects of global change on important ecological processes such as desertification. In mediterranean regions, due to the great spatio-temporal variability of mediterranean environmental conditions, tree rings are sometimes not formed. Often, clear seasonality is lacking, and vegetation activity is not always associated with regular dormancy periods. We present examples of tree-ring morphology of five species (Arbutus unedo, Fraxinus ornus, Quercus cerris, Q. ilex, Q. pubescens) sampled in Tuscany, Italy, focusing on the difficulties we encountered during the dating. We present an interpretation of anomalies found in the wood structure and, more generally, of cambial activity in such environments. Furthermore, we propose a classification of tree-ring formation in mediterranean environments. Mediterranean tree rings can be dated and used for dendrochronological purposes, but great care should be taken in selecting sampling sites, species and sample trees.

Climate↗

PubMed2003

Tracing carbon uptake from a natural CO2 spring into tree rings: an isotope approach.

We analyzed 14C, 13C and 18O isotope variations over a 50-year period in tree rings of Quercus ilex L. trees growing at a natural CO2 spring in a Mediterranean ecosystem. We compared trees from two sites, one with high and one with low exposure to CO2 from the spring. The spring CO2 is free of 14C. Thus, this carbon can be traced in the wood, and the amount originating from the spring calculated. The amount decreased over time, from about 40% in 1950 to 15% at present for the site near the spring, indicating a potential difficulty in the use of natural CO2 springs for elevated CO2 research. The reason for the decrease may be decreasing emission from the spring or changes in stand structure, e.g., growth of the canopy into regions with lower concentrations. We used the 14C-calculated CO2 concentration in the canopy to determine the 13C discrimination of the plants growing under elevated CO2 by calculating the effective canopy air 13C/12C isotopic composition. The trees near the spring showed a 2.5 per thousand larger 13C discrimination than the more distant trees at the beginning of the investigated period, i.e., for the young trees, but this difference gradually disappeared. Higher discrimination under elevated CO2 indicated reduced photosynthetic capacity or increased stomatal conductance. The latter assumption is unlikely as inferred from the 18O data, which were insensitive to CO2 concentration. In conclusion, we found evidence for a downward adjustment of photosynthesis under elevated CO2 in Q. ilex in this dry, nutrient-poor environment.

Carbon Dioxide↗

PubMed2002

Attending to objects: costs or benefits?

The single-object advantage is said to occur when performance is faster and/or more accurate when the two targets to be compared appear on one object than when they appear on two different objects. The single-object advantage has been interpreted to suggest that attention can select objects rather than unparsed regions of visual space. In five experiments we explored whether directing attention to one object rather than two objects produces a benefit or a minor cost. Participants were required to compare two target features that belonged to one object, to two objects, or did not belong to any object. In addition, we varied the relevance to the task of object-related global information, such as symmetry of the object and perceptual cluttering of the background. Results showed that attending to one object in comparison to attending to no object produced a benefit only when object-related global information was relevant to the task. In contrast, when object-related global information was irrelevant to the task, attending to one object produced a cost. Thus, it can be concluded that attending to an object does not produce an absolute benefit, but rather produces a smaller cost than attending to two objects.

Attention↗

PubMedDate not supplied

[The framing effect: medical implications].

Over the last 20 years, many studies explored how the way information is presented modifies choices. This sort of effect, referred to as "framing effects", typically consists of the inversion of choices when presenting structurally identical decision problems in different ways. It is a common assumption that physicians are unaffected (or less affected) by the surface description of a decision problem, because they are formally trained in medical decision making. However, several studies showed that framing effects occur even in the medical field. The complexity and variability of these effects are remarkable, making it necessary to distinguish among different framing effects, depending on whether the effect is obtained by modifying adjectives (attribute framing), goals of a behavior (goal framing), or the probability of an outcome (risky choice framing). A further reason for the high variability of the framing effects seems to be the domain of the decision problem, with different effects occurring in prevention decisions, disease-detection decisions, and treatment decisions. The present work reviews the studies on framing effects, in order to summarize them and clarify their possible role in medical decision making.

Decision Making↗