Fluoxetine and Prolonged Seizure.
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Letter↗
Biomedical subjects
Paolo Decina
Publications and source records attributed to Paolo Decina.
Reliability and Validity of Measures of Seizure Duration.
Two raters independently assessed seizure duration in single-channel electroencephalogram (EEG) records obtained in 479 electroconvulsive treatments of 52 patients. Ratings of seizure duration were highly reliable. The measures of EEG seizure duration were substantially associated with the duration of motor manifestations, supporting the validity of the EEG determinations. Confidence ratings of the clarity of the endpoint of EEG paroxysmal activity were unrelated to the duration of seizures in EEG and motor measures. The extent to which the EEG seizure activity extended beyond the motor manifestations was strongly related to the total duration of the EEG seizure manifestations and not to the duration of motor manifestations.
Journal Article↗
ECT-Induced Myoclonus.
We report a case of electroconvulsive therapy (ECT)-induced myoclonus which occurred postictally following every treatment and was distinguished from continuing seizure activity by electroencephalogram (EEG) recordings. Subsequent treatment with amitriptyline resulted in an isolated episode of myoclonus that did not recur when the dosage of medication was increased. Besides the clinical implications, this sequence of events raises questions about the serotonin hypothesis of antidepressant-induced myoclonus.
Journal Article↗