Biomedical subjects

Paraschiva Cherecheş-Panţa

Publications and source records attributed to Paraschiva Cherecheş-Panţa.

6 recordsLinked to original sources

PubMedDate not supplied

[Prevalence of bronchial asthma in 7 years -old children in Cluj-Napoca, an ISAAC study].

The authors studied the prevalence of asthma in children of 7 years from Cluj Napoca and analyzed the possible risk factors. We used the questionnaire elaborated by International Study on Asthma and Allergic Diseases in Children (ISAAC) which allowed the comparison of our data with those from other countries. Anamnesis, functional tests and allergic skin tests were performed in children with positive answers for questionnaire. 1334 children completed the study, 52.5% being males. Prevalence of asthma diagnosed previous to the questionnaire was of 5.7%, and it was higher in males (6.1%). By anamnesis, functional and skin tests data the diagnosis of asthma was made in a total of 217 children, so that the real prevalence of asthma is of 16.3% in this age group. Maternal smoking during the first year of life was significantly higher in children with wheezing. The high number of respiratory tract infections in the first year of life could also play a role. In conclusion, prevalence of asthma diagnosed in children of 7 years of age from Cluj Napoca is of 5.7% with a real prevalence of disease that seems to be much higher, of 16.3%. Maternal smoking represents a risk factor correlated with wheezing.

Asthma↗

PubMedDate not supplied

[Effectiveness of antireflux therapy in asthmatic children with gastroesophageal reflux disease].

There is an increased interest within literature regarding the relationship between gastro-esophageal reflux disease and asthma. The study was performed to assess the efficiency of antireflux therapy in asthmatic children. In a group of asthmatic children (n = 34, 22 male, age range: 2, 5-17 years) the pulmonary function tests were made by means of spirometry in those patients in which reflux disease was diagnosed by means of 24h esophageal pH-monitoring and upper digestive endoscopy. All these patients were reevaluated by means of spirometry 3 months after the antireflux therapy with ranitidine and cisapride added to antiasthmatic therapy. Three months later the results showed a significant decrease in frequency of asthma exacerbations from 3.18 +/- 4.86 to 0.45 +/- 0.80 (p = 0.016). There is also a significant increase of FEV1 (p = 0.04) and of FEV1/FVC (p = 0.018) in asthmatic patients with reflux disease and a positive symptomatic index, and of FEV1/FVC (p = 0.002) in all asthmatic children with abnormal gastro-esophageal reflux respectively. In conclusion, by adding antireflux therapy in asthmatic children there is a significant improvement in clinical and some of functional parameters.

Adolescent↗

PubMedDate not supplied

[Gastroesophageal reflux in asthmatic children: prevalence and pathogenic role].

The relationship of gastroesophageal reflux disease and asthma is controversial. This study was performed to assess the prevalence of pathologic gastroesophageal reflux and its effect on pulmonary function tests in asthmatic children. The following study protocol was performed in a group of asthmatic children (n = 34, 22 male, age range: 2, 5-17 years): diagnosis of pathologic gastroesophageal reflux by means of 24h esophageal pH-monitoring; diagnosis of reflux esophagitis by means of upper digestive endoscopy and pulmonary function tests by means of spirometry. The results show a high prevalence (87%) of pathologic gastroesophageal reflux in asthmatic children. Additionally, there is an inverse correlation (r = -0.67) between the severity of pathologic gastroesophageal reflux and FEV1/FVC. In conclusion, there is a high prevalence of pathologic gastro-esophageal reflux in asthmatic children, contributing to asthma severity.

Adolescent↗

PubMedDate not supplied

[Evaluation of quality of life in children with bronchial asthma].

Asthma affects children physically, psychologically and socially. The quality of life is a subjective parameter that evaluates the impact of asthma on daily life of the child. The authors evaluated the evolution of the quality of life score in children with persistent asthma treated with controllers, during one year, and the correlation between the quality of life score and pulmonary function parameters. The evaluation of the quality of life was based on a questionnaire with 23 items (PA QLQ), which was applied on 64 children with asthma. The quality of life score was evaluated initially and every 3 months. Pulmonary function tests were measured by spirometry every 3 months and children recorded PEF twice daily At the end of the study the authors revealed the improvement of the quality of life score in 87% of children. Initially the value of the general score of quality of life was of 4.78 +/- 1.09 and it increased up to 6.53 +/- 0.56 (p = 0.0001) after 12 months. We noticed significant improvement of the scores for symptoms, activities and emotions, and also of circadian variation of PEF (p = 0.002). We revealed a relatively poor reverse correlation between general score of the quality of life and circadian variation of PEF (r = - 0.330). In conclusion, the evaluation of quality of life might appreciate the clinical course of asthma patients. Based on this results the authors suggest the use of the evaluation of the quality of life as a complementary method to the classical methods used for asthma monitoring in children.

Adolescent↗

PubMedDate not supplied

[Quality of life in children with bronchial asthma and allergic rhinitis].

The quality of life is a subjective parameter that evaluates the impact of asthma on daily life of the child. The authors evaluated the evolution of the quality of life score in children with persistent asthma and analyzed the impact of association of allergic rhinitis on this parameter. The evaluation of the quality of life was based on a questionnaire with 23 items (PAQLQ), which was applied on 54 children with asthma (35 of them having rhinitis allergic associated to asthma). The quality of life score was evaluated initial and every 3 months, during one year. At the end of the study the authors revealed the improvement of the quality of life score in 87% of children, with significant improvement of the scores for symptoms, activities and emotions (p=0.002). There were no significant differences between the 19 patients with only asthma as compared with the 35 patients that had both asthma and allergic rhinitis either at the beginning of the study (p = 0,19) or after 12 months of follow-up (p = 0,34). In conclusion, allergic rhinitis is frequently associated with asthma in children, but its impact on the quality of life is not significant.

Adolescent↗

PubMedDate not supplied

[Askin tumor. Consideration on a case].

The authors present the case of a male patient of 9 years of age admitted for thoracic pain. The clinical evaluation and the imaging exams (chest X-ray, ultrasonography exam of the chest and thoracic computer tomography) reveal a tumor of the thoracic wall. The child was referred to the surgery. It was revealed an invasive tumoral mass of bone origin. At the pathological exam the tumor presented an aspect of Askin tumor. The authors discuss the theoretical aspects correlated with the diagnosis of Askin tumor, based on the presented case.

Child↗