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Pascal Zesiger

Publications and source records attributed to Pascal Zesiger.

4 recordsLinked to original sources

Computer-based measurement of letter and word acuity.

Determining causes of poor reading ability is an important step in trying to ameliorate reading performance in low-vision patients. One important parameter is word acuity. The principal aim of the current study is to develop a method to reliably measure acuities for isolated lowercase letters and words of differing length that can be used to test low-vision patients. Using isolated stimuli means that testing is relatively free of potential crowding and/or distracting attentional effects from surrounding words, it is unambiguous which stimulus subjects are trying to read and response times can be recorded for each stimulus. Across a series of experiments, subjects with normal vision were asked to read isolated lowercase single letters and lowercase words of 4, 7 and 10 letters, in separate tests. Acuities for uppercase Sloan letters were also measured to provide a reference, as they are commonly used to measure visual acuity. Each test was based upon the design principles and scoring procedures used in the Bailey-Lovie and ETDRS charts. Acuities for uppercase Sloan letters were found to be equivalent whether measured using ETDRS charts or the computer-based method. Measurement of acuities for lowercase single letters and lowercase words of 4, 7 and 10 letters had a reliability that was no worse than acuities for uppercase Sloan letters. Lowercase word acuities were essentially independent of word length. Acuities for single lowercase letters and lowercase words were slightly better than uppercase Sloan letters acuity. Optimal processing of lowercase single letters and 4-, 7- and 10-letter words occurred at character sizes that were at least 0.2-0.40 log MAR above acuity threshold, i.e. between 1.5 and 3 times threshold acuity for that particular stimulus. In general, critical character sizes appear similar across word lengths as progressive increases or decreases in these values were not observed as a function of the number of letters in the stimulus. We conclude that a computer-based method of stimulus presentation can be used to obtain highly repeatable measures of acuity for lowercase single letters and lowercase words in normal vision.

Adult↗

Acquired epileptic dysgraphia: a longitudinal study.

A male presenting with benign partial epilepsy with rolandic spikes from the age of 7 years was evaluated at age 11 years for worsening of his epilepsy associated with a specific regression of graphomotor skills. A longitudinal study over nearly 2 years showed an improvement in handwriting to an almost normal level under modified antiepileptic therapy. A detailed analysis with a computer-monitored graphics table showed at first a rapid improvement of skills followed by protracted slower progress. We argue that the initial rapid recovery of skills was directly linked to the improvement of his epilepsy. The slower late acquisition of motor programmes that had never been fully established was due to long-standing interference by his epilepsy. The specificity of the deficit within the graphomotor system and its possible neurobiological basis are also discussed. The analytical method and approach used in a single patient might provide an example for other patients in whom epilepsy can interfere in the acquisition, progress, and maintenance of new skills and can be responsible for selective deficits.

Aging↗

Preserved visual function in a case of occipitoparietal microgyria.

A 20-year-old man with bilateral parasagittal occipitoparietal polymicrogyria and epilepsy, from whom normal functional magnetic resonance imaging and electroencephalogram responses to visual stimuli were obtained, was found to have no visual perceptual deficits. This suggests that microgyric cortex can perform normal visual functions, despite its gross structural abnormalities.

Adolescent↗

Verbal structure of numerals and digits handwriting: new evidence from kinematics.

Two experiments used a digitizing tablet to analyse the temporal, spatial, and kinematic characteristics of handwritten production of arabic numbers. They addressed a specific issue of the numerical domain: Does the lexical and syntactic structure of verbal numerals influence the production of arabic numerals (Experiments 1 and 2), even after enforced semantic processing in a comparison task (Experiment 2)? Subjects had to write multi-digit arabic numerals (e.g., 1200) presented in two different verbal structures: a multiplicative one (e.g., teen-hundred, douze cents (twelve hundred)) or an additive one (e.g., thousand-unit-hundred, mille deux cents (one thousand two hundred)). Results show differences in the inter-digit jumps that reflect the influence of the structure of verbal numerals, even after the semantic task. This finding is discussed with regard to different models of number transcoding (McCloskey, Caramazza, & Basili, 1985; Power & Dal Martello, 1990, 1997).

Adult↗