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Biomedical subjects

Patrick A Bovier

Publications and source records attributed to Patrick A Bovier.

At least 19 recordsLinked to original sources
PubMed2007

Use of tobacco and alcohol by Swiss primary care physicians: a cross-sectional survey.

BACKGROUND: Health behaviours among doctors has been suggested to be an important marker of how harmful lifestyle behaviours are perceived. In several countries, decrease in smoking among physicians was spectacular, indicating that the hazard was well known. Historical data have shown that because of their higher socio-economical status physicians take up smoking earlier. When the dangers of smoking become better known, physicians began to give up smoking at a higher rate than the general population. For alcohol consumption, the situation is quite different: prevalence is still very high among physicians and the dangers are not so well perceived. To study the situation in Switzerland, data of a national survey were analysed to determine the prevalence of smoking and alcohol drinking among primary care physicians. METHODS: 2,756 randomly selected practitioners were surveyed to assess subjective mental and physical health and their determinants, including smoking and drinking behaviours. Physicians were categorised as never smokers, current smokers and former smokers, as well as non drinkers, drinkers (AUDIT-C < 4 for women and < 5 for men) and at risk drinkers (higher scores). RESULTS: 1'784 physicians (65%) responded (men 84%, mean age 51 years). Twelve percent were current smokers and 22% former smokers. Sixty six percent were drinkers and 30% at risk drinkers. Only 4% were never smokers and non drinkers. Forty eight percent of current smokers were also at risk drinkers and 16% of at risk drinkers were also current smokers. Smoking and at risk drinking were more frequent among men, middle aged physicians and physicians living alone. When compared to a random sample of the Swiss population, primary care physicians were two to three times less likely to be active smokers (12% vs. 30%), but were more likely to be drinkers (96% vs. 78%), and twice more likely to be at risk drinkers (30% vs. 15%). CONCLUSION: The prevalence of current smokers among Swiss primary care physicians was much lower than in the general population in Switzerland, reflecting that the hazards of smoking are well known to doctors. However, the opposite was found for alcohol use, underlining the importance of making efforts in this area to increase awareness among physicians of the dangers of alcohol consumption.

Adult↗
PubMed2006

Importance of lifestyle counselling by primary care physicians for diabetic patients.

OBJECTIVE: To identify diabetic patients' characteristics and medical care factors associated with recommended glycaemic control (HbA(1c) < or =7%). METHODS: As part of a cross-sectional assessment of diabetes care involving 204 Swiss primary care physicians, we identified 366 diabetic patients with a recent HbA(1c) value. Cross-tabulations and X(2) tests were used to explore the association of patients' sociodemographic and disease characteristics and medical care characteristics with HbA(1c) < or =7%. Significant factors were included in a regression logistic model to identify multivariate predictors of HbA(1c) < or =7%. RESULTS: HbA(1c) values were in the recommended range for 57% of the patients. A less than five years' history of diabetes, absence of followup by a diabetes specialist, absence of microalbuminuria or retinopathy, adherence to dietary and physical activity counselling, no participation in a diabetic education programme, no glycaemic self-monitoring, oral or no antidiabetic therapy and influenza vaccine in the last 12 months were associated with HbA(1c) < or =7%. In the multivariate analysis, HbA(1c) < or =7% remained associated with a less than five years diabetes history (odds ratio [OR] 2.5, 95% confidence interval [CI] 1.5-4.3), as well as patients' adherence to dietary (OR 1.9, 95% CI 1.2-3.0) and physical activity counselling (OR 1.8, 95% CI 1.1-2.9). CONCLUSION: In this sample of diabetic patients, adherence to dietary and physical activity counselling were associated with better glycaemic control. Further research should focus on the importance of appropriate lifestyle counselling by Swiss primary care physicians, ideally in prospective trials using objective and reproducible measures of patients' observance.

Adult↗
PubMed2006

Posttraumatic stress disorder and the use of general health services in postwar Kosovo.

Studies conducted in high-income countries have demonstrated that posttraumatic stress symptoms are positively correlated with increased use of general health services; however, comparative data are lacking in postwar settings. This survey was conducted in Kosovo after the end of the conflict; 996 people, age 16 or older, were interviewed. Older age, lower education level, worse physical health, and current diagnosis of posttraumatic stress disorder (PTSD) were associated with higher use of any health services. After adjusting for gender, age, place of residence, type of education, poverty, refugee status, and subjective physical health, PTSD remained associated with an increased use of most health care services. Our results underline the importance of taking into account PTSD when restoring health services in postwar countries.

Adolescent↗
PubMed2006

Screening for major depression and posttraumatic stress disorder among asylum seekers: adapting a standardized instrument to the social and cultural context.

OBJECTIVE: To adapt the PTSD and MDE sections of a validated psychiatric diagnostic instrument, we used the Mini International Neuropsychiatric Interview (MINI) during an initial health assessment into a primary care facility for asylum seekers. METHOD: A 3-step process was carried out. First, items of the original version of the MINI were adapted to the specific context of life of asylum seekers in the host country (by a multidisciplinary group that included public health nurses, a primary care physician, a psychologist, a psychiatrist, and an epidemiologist). Second, we submitted the reworded and original versions of the MINI to 14 interpreters' who tested for general and cultural acceptability. Each diagnostic criterion was rated according to interpreters' comments on a 4-point Likert scale (1 = an item good for translation and 4 = an unusable or completely inadequate item). In the third step, we rephrased the most problematic items identified by the interpreters. RESULTS: Some original items were considered particularly ill-adapted for this context, and 4 had to be dropped. This final rewording took into account cultural inadequacies and lack of structure (including temporal organization) of the everyday life of newly arrived asylum seekers. CONCLUSION: The reworded MINI was successfully tested, and its items are presented in the final part of the study.

Comorbidity↗
PubMed2005

Cost-consciousness among Swiss doctors: a cross-sectional survey.

BACKGROUND: Knowing what influences physicians attitudes toward health care costs is an important matter, because most health care expenditures are the results of doctors' decisions. Many decisions regarding medical tests and treatments are influenced by factors other than the expected benefit to the patient, including the doctor's demographic characteristics and concerns about cost and income. METHODS: Doctors (n = 1184) in Geneva, Switzerland, answered questions about their cost-consciousness, practice patterns (medical specialty, public.vs. private sector, number of patients per week, time spent with a new patient), work satisfaction, and stress from uncertainty. General linear models were used to identify independent risk factors of higher cost-consciousness. RESULTS: Most doctors agreed that trying to contain costs was their responsibility ("agree" or "totally agree": 90%) and that they should take a more prominent role in limiting the use of unnecessary tests (92%); most disagreed that doctors are too busy to worry about costs (69%) and that the cost of health care is only important if the patient has to pay for it out-of-pocket (88%). In multivariate analyses, cost-consciousness was higher among doctors in the public sector, those who saw fewer patients per week, who were most tolerant of uncertainty, and who were most satisfied with their work. CONCLUSION: Thus even in a setting with very high health care expenditures, doctors' stated cost-consciousness appeared to be generally high, even though it was not uniformly distributed among them.

Adult↗
PubMed2005

Swiss primary care physicians reporting of utility and use of recommended vaccinations for adults.

QUESTION: To determine how recommended vaccinations in adults are perceived and used by primary care physicians in Switzerland. METHODS: A cross-sectional mail survey of primary care physicians randomly selected from the register of the Swiss medical association was conducted, including specific items measuring perceived utility and reported use for fourteen recommended vaccinations for adults. The answers were standardized to have a minimum of 0 and a maximum of 100. Other items assessed socio-demographic and work characteristics, opinion regarding the use of vaccinations, sources of recommendations used for vaccinations, and patient and organisational barriers. Frequency tables and crosstabulations were used to describe differences in perceived utility and reported use across these characteristics. RESULTS: After three reminders, 1166 physicians participated in the survey (response rate 64%). Perceived utility was the highest for rubella immunisation in young women (93.6; 95% CI: 92.8 to 94.3) and hepatitis B immunisation in high-risk adults (91.9; 95% CI: 91.0 to 92.7); it was the lowest for immunisations against measles (56.7; 95% CI: 55.3 to 58.2) and pneumococcal diseases (55.2; 95% CI: 53.8 to 56.7). The highest levels of use were reported for diphtheria-tetanus booster after a wound (91.7; 95% CI: 90.7 to 92.7) and poliomyelitis immunisation of travelers (89.5; 95% CI: 88.4 to 90.6); the lowest for immunisations against measles (40.3; 95% CI: 38.5 to 42.1) and pneumococcal diseases (33.3; 95% CI: 31.8 to 34.8). Lower reported use was associated with reports of physicians not having the time to verify vaccination status and convince a patient to be immunised, and other logistic issues related to physician's practice, but not with reports of patient's refusal of immunisation. CONCLUSION: There are several avenues to strengthen promotion programs aiming at improving immunisation use by Swiss primary care physicians in adults, among which a high better recognition of time spent for health promotion activities should have priority.

Adult↗
PubMed2005

Interchangeability and tolerability of a virosomal and an aluminum-adsorbed hepatitis A vaccine.

The interchangeability of virosomal (Epaxal) and aluminum-adsorbed (Havrix 1440) hepatitis A virus (HAV) vaccines was studied in 111 healthy adults who were vaccinated in a randomized, single-blind, crossover clinical trial. Anti-HAV antibody titers were measured at days 0 (first dose), 14, and 28, and months 3, 6, 12 (second dose), 13, 24, 36, 48, 60 and 72. Most subjects (>95%) had sero-converted 14 days after the first dose of either vaccine. The second dose with either vaccine induced a high antibody response in all vaccines, irrespective of the type of vaccine administered as the first dose. Although both vaccines were well tolerated, the incidence of local adverse events (in particular pain) was significantly lower in subjects receiving the virosomal vaccine. Six-year follow-up data did not reveal any significant differences between the vaccination groups.

Adjuvants, Immunologic↗
PubMed2005

Nutrient intake and performance during a mountain marathon: an observational study.

In order to study nutrient intake of amateur runners during a mountain marathon, compliance with recommendations, and association with performance, an intake of 42 participants in a Swiss mountain marathon was assessed by direct observation. Data on demographics, dietary preparation and race experience were obtained by questionnaires. Anthropometrical measures were performed before and after the race. Mean hourly intakes (SD) of fluid, carbohydrate, energy and sodium were 545 (158) ml, 31 (14) g, 141 (63) kcal [or 590 (264) kJ], and 150 (203) mg respectively. A third of the runners drank 600 ml h(-1) or more, 52% consumed less than 30 g h(-1 )carbohydrates, 95% consumed less than 500 mg h(-1) sodium. Mean weight loss was 4 (1.5) kg; 30 runners (71%) lost over 3% body mass. Mean running time was 7 h 3 min (1 h 17 min). Most participants failed to meet nutritional recommendations. None were at risk of overhydration. Body composition and race experience were correlated with performance, but not nutrient intake. Because experienced runners are well trained, fitter, and know better their personal needs during such a race, it is difficult to disentangle these associations. As causal relationship cannot be proven with this cross-sectional design, non-compliance with intake recommendations requires additional experimental research on the impact of nutrient intake on field performance.

Adaptation, Physiological↗
PubMed2005

Nonresponse bias in a survey of patient perceptions of hospital care.

BACKGROUND: Incomplete participation is of particular concern for surveys of patient perceptions of care because patients who have negative opinions may be least likely to participate. OBJECTIVE: We sought to examine indirect evidence of nonresponse bias. DESIGN: We re-analyzed data from a cross-sectional patient survey. SUBJECTS: Our subjects were patients discharged from a Swiss hospital (n = 2156). MEASURES: We measured the following: (1) an observed problem score, based on 15 key items of the Picker Patient Experience questionnaire, (2) a predicted problem score, and (3) a participation propensity score. The latter scores were computed for all eligible patients, including those who did not return the survey, from routinely available baseline data. RESULTS: The participation rate was 70% (n = 1518), and the mean problem score was 29.9 (SD 23.8). Early respondents reported significantly fewer problems than late respondents (28.6 versus 32.9, P = 0.001). Participation propensity scores were progressively lower in early respondents (mean 74.2), late respondents (70.7), and nonrespondents (63.9, P < 0.001); the pattern was similar for predicted problem scores (early respondents: 29.5; late respondents: 30.5; nonrespondents: 33.4, P < 0.001). The propensity to participate was negatively associated with the problem score (Pearson r = -0.19). Finally, predictors of participation were similar to predictors of problem scores. CONCLUSIONS: The tendency to participate in the survey was negatively associated with the report of problems during hospitalization. Nevertheless, increasing participation from 30% to 70% had only a modest influence on the final conclusions of the survey.

Adolescent↗
PubMed2005

Patient reports of undesirable events during hospitalization.

BACKGROUND: Thus far, incident reporting in health care has relied on health professionals. However, patients too may be able to signal the occurrence of undesirable events. OBJECTIVE: To estimate the frequency of undesirable events reported by recently discharged patients, and to identify correlates of undesirable events. DESIGN: Mailed patient survey. SETTING: Swiss public teaching hospital. PARTICIPANTS: Adult patients (N=1,518) discharged from hospital. MEASUREMENTS: Self-reports of 27 undesirable events during hospitalization, including 9 medical complications, 9 interpersonal problems, and 9 incidents related to the health care process. RESULTS: Most survey respondents (1,433, 94.4%) completed the section about undesirable events, and 725 (50.6%) reported at least 1 event. The most frequent events were phlebitis (11.0%), unavailable medical record (9.5%), failure to respect confidentiality (8.4%), and hospital-acquired infection (8.2%). The odds of an unfavorable rating increased with each additional interpersonal problem (odds ratio [OR] 1.6, 95% confidence interval [CI] 1.3 to 1.8), each additional process-related problem (OR 1.5, 95% CI 1.3 to 1.9), but not with each additional medical complication (OR 1.0, 95% CI 0.9 to 1.2). Longer duration of stay, poor health, and depressed mood were all related to a greater reported frequency of undesirable events. CONCLUSION: Patients are able to report undesirable events that occur during hospital care. Such events occur in about a half of the hospitalizations, and have a negative impact on satisfaction with care.

Health Care Surveys↗
PubMed2004

Self-reported management of pain in hospitalized patients: link between process and outcome.

PURPOSE: Hospitalized patients commonly experience pain. We investigated the association between patients' reported use of recommended pain management practices and overall pain relief. METHODS: All adult patients discharged during a 1-month period from a Swiss teaching hospital were invited to complete a mailed survey that included the Picker patient experience questionnaire, questions on pain relief during hospitalization, and questions on various procedures that are recommended as standards of pain management. RESULTS: Of 2156 eligible patients, 1518 (70%) participated. Sixty-nine percent (n = 1050) had experienced pain during their hospital stay, of whom 71% (n = 697/978) reported complete pain relief. After adjustment for sex, age, general health, and hospital department, pain relief was associated independently with availability of physicians (odds ratio [OR] = 11; 95% confidence interval [CI]: 3.3 to 36 for excellent vs. poor availability), having received information about pain and its management (OR = 2.8; 95% CI: 1.8 to 4.2), regular pain assessment (OR = 1.8; 95% CI: 1.2 to 2.8), modification of pain treatment when ineffective (OR = 3.0; 95% CI: 1.6 to 5.6), and waiting less than 10 minutes for pain medications (OR = 3.5; 95% CI: 1.9 to 6.6). CONCLUSION: Patient reports that recommended pain management procedures had been used were associated with better self-reported pain relief among hospitalized patients.

Adolescent↗
PubMed2004

Medical researchers evaluate their methodological skills.

BACKGROUND AND OBJECTIVE: Clinical epidemiology and statistics skills of clinical researchers are often limited. We assessed methodological skills of medical researchers and identified factors associated with higher skill levels. METHODS: In a cross-sectional mail survey at two Swiss teaching hospitals, participants (N=409) rated their ability to perform 26 research-related activities, such as identifying the research question, selecting a study design, computing the required sample size, performing data analysis, and reporting results. RESULTS: The proportion of respondents who were able to perform a specific activity was 33.2% on average, ranging from 1.5% for "numerical statistics (bootstrap, simulation, cross-validation,...)" to 76.0% for "oral presentation of results." The overall skill level (expressed as a percentage of the 26 activities) was associated with principal investigator experience (+8.7%), greater percentage of time devoted to research (+12.4% for near full-time versus no time commitment), years of research experience (+17.6% for 15-40 years versus 0 years), past number of clinical research projects (+18.0% for 15-230 projects versus 0-1 projects), and hours of formal methodological training (+32.6% for 200-1200 hours versus 0-9 hours). CONCLUSION: Self-reported methodological skills were generally modest. The most important covariates of skill levels were current time commitment to research, past experience, and formal training.

Adult↗
PubMed2004

Perceived stress, internal resources, and social support as determinants of mental health among young adults.

BACKGROUND: Mental health is a central determinant of quality of life. While psychiatric morbidity of populations has been studied extensively, the role of perceived stress, social support, and internal resources as determinant of health is still poorly understood. METHODS: We surveyed 2000 randomly selected university students. Perceived stress was measured by the Brief Encounter Psychosocial Instrument, social support by the Duke-UNC Functional Social Support Questionnaire, internal resources (mastery and self-esteem) by a brief version of the Pearlin coping questionnaire. Linear regression models were used to explore the relationships between these variables and mental health, based on the SF-12 health survey. RESULTS: After two reminders, 1257 students answered the questionnaire. In bivariate analysis, mental health was negatively associated with stress and positively associated with internal resources and social support (all p-values < 0.001). In multiple regression analysis, internal resources were positively associated with mental health, and buffered the negative impact of stress on mental health. Internal resources and stress mediated the positive impact of social support on mental health. CONCLUSIONS: Our data confirm that perceived stress is an important risk factor for low mental health and suggest that mastery and self-esteem are important protective factors of mental health among young adults.

Adaptation, Psychological↗
PubMed2004

Health and happiness in young Swiss adults.

PURPOSE: To explore whether self-reported happiness is associated with mental and physical health status among young adults. METHODS: Cross-sectional survey of 1257 randomly selected university students in Geneva, Switzerland. The questionnaire included an item that probed the feeling of happiness in the past month, the Short Form-12 health survey (from which mental and physical health scores were computed), scales to measure self-esteem, stress, and social support, reports of various life problems, and sociodemographic information. RESULTS: Most participants felt happy all of the time or most of the time (63%). In multivariate analysis, feeling happy all or most of the time was strongly associated with better mental health (odds ratios for consecutive quartiles of mental health scores: 1.0 (reference), 6.8 (95% confidence interval (CI): 4.5-10.1), 19.2 (95% CI: 12.2-30.2), 39.9 (95% CI: 22.4-71.0)), but also with the feeling of getting enough love and affection (item from the social support scale, odds ratio: 1.9; 95% CI: 1.4-2.7), female sex (odds ratio: 1.5; 95% CI: 1.1-2.1), being Swiss (odds ratio: 1.8; 95% CI: 1.3-2.5), and higher self-esteem (odds ratios for consecutive quartiles ranged from 1.0 to 3.5, 95% CI: 2.1-5.8). The association between happiness and physical health was weak and statistically non-significant. CONCLUSIONS: The strong association between happiness and mental health suggests that asking people if they are happy may help identify mental health care needs. Self-reported happiness may also be a useful outcome measure for evaluation of health interventions.

Adult↗
PubMed2004

Determinants of postconflict symptoms in Albanian Kosovars.

During the period from 1998 to 1999, more than 1 million civilians from the province of Kosovo in the Balkans were displaced as a consequence of organized violence and war. The aim of the present study was to determine the prevalence of posttraumatic stress disorder (PTSD) in a sample of the Albanian Kosovar population more than 2 years after the end of the conflict and to assess the effect of exposure to war-related events. A total of 340 households were randomly selected among 12,900 families returned from a country of asylum (Switzerland). All adults in each household were invited to participate (N = 996). The following instruments were used: the Albanian translations of the PTSD section of the Mini International Neuropsychiatric Interview and of the Medical Outcomes Study 36-Item Short Form, and a list of traumatic events adapted from the Harvard Trauma Questionnaire. The overall prevalence of PTSD was 23.5%. A strong cumulative effect of trauma was observed, with odds ratios for PTSD rising steeply with the number of events to which people were exposed. After taking into account traumatic events, multivariable analysis indicated that female gender, older age, and having left Kosovo during the conflict were significantly associated with higher frequency of PTSD, whereas significant heterogeneity among municipalities was observed. Stratified analysis for people who stayed and left the province during the war suggested that different patterns of trauma may be relevant in the two subsamples, with forced separation and isolation strongly associated with PTSD in people who stayed in Kosovo. PTSD diagnosis was also significantly associated with lower scores on all dimensions of the Medical Outcomes Study 36-Item Short Form and lower economic status. The results suggest that responding to medium-term and long-term mental health consequences of conflict is a necessary task for the global rehabilitation of health care systems in a war devastated country.

Adolescent↗
PubMed2004

Impact of snake bites and determinants of fatal outcomes in southeastern Nepal.

Current available data on snake bites in Nepal are based solely on hospital statistics. This community-based study aimed at evaluating the impact of snake bites and determining the risk factors associated with a fatal outcome in southeastern Nepal. A total of 1,817 households, selected by a random proportionate sampling method, were visited by trained field workers in five villages. Extensive data from snake bite victims during the 14 previous months were recorded and analyzed. One hundred forty-three snake bites including 75 bites with signs of envenoming were reported (annual incidence = 1,162/100,000 and 604/100,000, respectively), resulting in 20 deaths (annual mortality rate = 162/100,000). Characteristics of krait bites such as bites occurring inside the house, while resting, and between midnight and 6:00 am were all factors associated with an increased risk of death, as were an initial consultation with a traditional healer, a long delay before transport, and a lack of available transport. An initial transfer to a specialized treatment center and transport by motorcycle were strong protective factors. Among the 123 survivors, wounds required dressing and surgery in 30 (24%) and 10 (8%) victims, respectively, the mean working incapacity period was 15 days, and the mean out-of-pocket expense was 69 U.S. dollars. Snake bite is a major but neglected public health problem in southeastern Nepal. Public health interventions should focus on improving victims' rapid access to anti-snake venom serum by promoting immediate and fast transport to adequate treatment centers, particularly for bites occurring at night.

Adult↗
PubMed2004

Card agglutination test for trypanosomiasis (CATT) end-dilution titer and cerebrospinal fluid cell count as predictors of human African Trypanosomiasis (Trypanosoma brucei gambiense) among serologically suspected individuals in southern Sudan.

The diagnosis of human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense relies on an initial serologic screening with the card agglutination test for trypanosomiasis (CATT) for T. b. gambiense, followed by parasitologic confirmation in most endemic areas. Unfortunately, field parasitologic methods lack sensitivity and the management of serologically suspected individuals (i.e., individuals with a positive CATT result but negative parasitology) remains controversial. In Kajo-Keji County in southern Sudan, we prospectively collected sociodemographic and laboratory data of a cohort of 2,274 serologically suspected individuals. Thirty-three percent (n = 749) attended at least one follow-up visit and HAT was confirmed in 64 (9%) cases. Individuals with lower initial CATT-plasma (CATT-P) end-dilution titers had lowest risks (10.4 and 13.8/100 person-years for 1:4 and 1:8 titers, respectively) that significantly increased for higher dilutions: relative risks = 5.1 (95% confidence interval [CI] = 2.6-9.5) and 4.6 (95% CI = 2.8-9.8) for 1:16 and 1:32 titers, respectively. The cumulative yearly risk was also high (76%) in individuals found with 11-20 cells in the cerebrospinal fluid, but this involved only eight patients. Adjustment for potential confounders did not affect the results. In conclusion, treatment with pentamidine should be considered for all serologically suspected individuals with a CATT-P end-dilution titer >/= 1:16 in areas of a moderate to high prevalence of HAT.

Adolescent↗