Biomedical subjects
Publications and source records attributed to Patrick Choutet.
We report the first documented case of endocarditis in a man infected with Bartonella alsatica, which causes bacteremia in healthy wild rabbits. B. alsatica was identified by serology and culture and by PCR of an aortic valve specimen. B. alsatica should be added to the list of zoonotic agents of blood culture-negative endocarditis.
Microbial resistance to anti-infective drugs is a major public health threat. The phenomenon of selection has been amplified both in hospitals and in the community by increased antibiotic use. Antibiotic use in France is excessive. Good routine antimicrobial practices are crucial to control the spread of bacterial resistance. Antibiotic prescriptions have fallen by 17% since the beginning of a national control program in 2001.
Antibiotic use in France is excessive. This statement is regularly expressed. The comparison with usage in other European countries, the frequency of use in viral infections, the misuse, specifically in the duration of treatment is easy proof of this. However, does this excessive use really have negative consequences in terms of public health? Yes, through the development of antibiotic resistance in hospital bacteria and also in the community. The phenomenon of selection has been amplified as much in the hospital as in the community due to the increase in antibiotic use. It has been a problem that has been neglected for a long time due to the regular release of new antibiotics with better performance onto the market. More than ever, as with any side effect, it has to be taken into account with each prescription of an antibiotic. It encourages the development of a reservoir of resistant bacteria and creates a collective medical risk of the appearance of infections for which the choice of treatment is at best restricted and costly, and at worst inexistent.