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Biomedical subjects

Patrick Remington

Publications and source records attributed to Patrick Remington.

16 recordsLinked to original sources

Gender disparities in colorectal cancer screening: true or false?

To date, nearly all studies examining gender disparities in colorectal cancer screening report a lower endoscopic screening rate in women. Using a statewide claims database, gender differences in screening rates were analyzed in an attempt to validate gender disparities reported in prior survey-based studies. Procedural-level dataset containing all patient encounters for 2003 in which a colonoscopy or flexible sigmoidoscopy were performed was created. Procedures were selected using CPT codes and univariate analysis was performed using SAS v 8.0. Statewide for average-risk individuals 50 years or older, 65,232 endoscopic procedures were performed in 2003. The majority (83%) of endoscopic screening procedures were colonoscopies. Overall, the rate of screening in average-risk women 50 years or older (38 procedures/1000 people) was slightly lower than in men (42/1000) but not statistically significant. The rates of screening were higher in women before the age of 60 years and lower after the age of 60 years. No clinically significant difference was found in the type of screening procedure performed. Gender disparities in rates and types of colorectal cancer screening reported in prior survey studies are not validated in this patient encounter data study.

Adult↗

Disparities in oral and pharyngeal cancer incidence and mortality among Wisconsin residents, 1999-2002.

OBJECTIVE: Compare incidence, mortality, and trends of oral cancer (including the pharynx) in Wisconsin and the United States by race and gender from 1999-2002. METHODS: Age-adjusted incidence rates were compared using data from the Centers for Disease Control and Prevention (CDC WONDER). Mortality rates were compared using data from the Wisconsin Interactive Statistics on Health (WISH) and CDC US Cancer Statistics. RESULTS: Incidence rates for oral cancer were higher among males than females in both Wisconsin and the United States. Trends in the incidence rate show the gender disparity has not changed. Furthermore, the incidence rate for African American males is higher in Wisconsin than in the United States. Mortality rates for males were approximately 2 times higher than females in Wisconsin and the United States. Additionally, African American males are more likely than white males to die from this form of cancer, and the likelihood is higher in Wisconsin than in the United States (2.4 versus 1.8, respectively). CONCLUSION: Racial disparities in oral cancer for African American males are greater in Wisconsin than in the United States. This may result from variation in access to oral health care, tobacco and alcohol use, as well as limited resources in detection and prevention methods. Wisconsin should focus its oral cancer prevention activities on this high-risk group.

Black or African American↗

The silent epidemic among Wisconsin women: chronic obstructive pulmonary disease trends, 1980-2000.

PURPOSE: To investigate trends in mortality from chronic obstructive pulmonary disease (COPD) in Wisconsin. METHODS: COPD mortality data for those 45 years of age and older were extracted from the Centers for Disease Control and Prevention WONDER database and analyzed. Rates were adjusted to the 2000 US Census. RESULTS: In Wisconsin, the mortality rate from COPD increased by 88% between 1980 and 2000. A similar increase in COPD mortality occurred in the United States during this same period. Among Wisconsin males, the 33% increase from 1980-2000 was higher than the increase for US males. Likewise, the rate among Wisconsin females increased 3.9 times compared to an increase of 2.8 among US females. Unlike men, mortality increased in all age groups of women from 1980 to 2000. CONCLUSIONS: COPD mortality rates are increasing dramatically in Wisconsin, especially among women. Long-term trends in smoking do not explain the increases in COPD death rates among women. Other possible reasons include changes in the pattern of smoking or in the type of cigarette smoked, or women may be more susceptible to lung disease. Wisconsin physicians should target women for diagnosis and treatment of COPD and for smoking cessation and prevention.

Aged↗

Overweight among high school children: how does Wisconsin rank?

BACKGROUND: The rate of childhood overweight is increasing among our nation's youth. This epidemic has led to an increase of comorbidities such as high blood pressure and diabetes being treated in the pediatric population. This paper analyzes self-reported heights and weights to determine trends in the prevalence of overweight among US students in grades 9-12. METHODS: Data from the Youth Risk Behavior Surveillance System from 1999 to 2003 were used to determine the prevalence of overweight--which is defined as a BMI < 85th percentile for age and gender--in 41 participating states. (Data from the "at risk of overweight" group [defined as BMI > or = 85 percentile and < 95 percentile] and the "overweight" group [defined as BMI > or = 95 percentile] were combined and labeled as "overweight" [BMI > or = 85 percentile] to make communication of results more clear.) RESULTS: The prevalence of overweight adolescents in Wisconsin increased slightly during the past 4 years, from 22.6% in 1999 to 24.1% in 2003, with adolescent males 50% more likely than females to be overweight. In 2003, Wisconsin's rate of overweight was the 14th lowest among 41 states reporting to the Centers for Disease Control and Prevention. (Colorado is lowest at 15.7% and Mississippi is highest at 31.4%.) When examining races separately, Wisconsin's ranking decreases slightly, but remains in the top half of all states reporting. CONCLUSIONS: The prevalence of childhood overweight in Wisconsin appears to be rising, following the national trend. The prevalence of overweight among high school students is lowest in the Rocky Mountain states. Understanding reasons for these differences may shed light on strategies to decrease overweight in Wisconsin.

Adolescent↗

Model for end stage liver disease score predicts mortality across a broad spectrum of liver disease.

BACKGROUND/AIMS: The utility of the model for end stage liver disease (MELD) score in non-transplant patients, particularly in those with less severe chronic liver disease remains uncertain. We studied and compared the predictive abilities of the MELD score and the Child-Turcotte-Pugh (CTP) score for intermediate (1-year) and long-term (5-year) mortality. METHODS: One thousand six hundred and eleven patients with chronic liver disease were studied. Observed and predicted survival curves were plotted to evaluate the predictive ability of the MELD score for survival. Receiver operating characteristic (ROC) curves was used to compare the MELD and CTP score. A multivariable model was constructed to examine predictors of mortality. RESULTS: The MELD score was a good predictor of 1-year mortality in chronic liver disease (c-statistics for all subgroups >/=0.75) and of 3- and 6-month mortality in alcoholic hepatitis (c-statistic >/=0.83). The CTP score had similar predictive abilities as the MELD. Hepatic encephalopathy was a strong independent predictor of death (Hazard ratio-2.8, P<0.0001). CONCLUSIONS: The MELD score is a valid prognostic score for intermediate term mortality in a heterogeneous population with chronic liver disease although the CTP score is equivalent in predicting survival. Inclusion of hepatic encephalopathy adds additional prognostic value to the MELD score.

Female↗

The prevalence of alcohol-induced liver disease and hepatitis C and their interaction in a tertiary care setting.

BACKGROUND & AIMS: We examined the prevalence and clinical characteristics of alcohol-induced liver disease (ALD) in patients referred to a tertiary care center and examined the interaction between ALD and hepatitis C virus (HCV) in a longitudinal survival model. METHODS: A total of 1611 patients with chronic liver disease referred to a tertiary care center between 1994 and 2001 were analyzed. The survival of ALD, HCV, and the combination of the 2 (ALD + HCV) was compared in cirrhotic and precirrhotic patients by using Kaplan-Meier estimates. A Cox proportional hazards model was used to examine the independent effects of predictors on survival. RESULTS: ALD comprised 31% of the cohort, ALD + HCV comprised 14%, HCV comprised 22%, and the rest comprised 33%. The survival of precirrhotic patients with HCV was significantly better than the survival of those with ALD (hazard ratio, 0.27; P = 0.0006) over long-term and 1-year (hazard ratio, 0.24; P = 0.016) follow-up periods. There was no difference in survival between patients with ALD and ALD + HCV ( P = 0.62). In patients with cirrhosis, survival did not differ by cause; decompensated liver disease (hazard ratio, 1.67; P = 0.004) and continued alcohol abuse (hazard ratio, 2.19; P = 0.002) predicted worse survival in this group. CONCLUSIONS: ALD with HCV remains a prevalent cause of chronic liver disease in patients referred to a U.S. tertiary care center. In patients with ALD, the addition of HCV does not change survival, suggesting alcoholism is the driving force for mortality in patients coming to clinical attention. In patients with cirrhosis, ongoing excessive alcohol use and complications of end-stage liver disease drive mortality, irrespective of the underlying cause of chronic liver disease.

Age Factors↗

Clean indoor air policies in Wisconsin workplaces.

OBJECTIVE: To describe the nature and extent of workplace environmental tobacco smoke exposures in Wisconsin. METHODS: Descriptive data and confidence intervals from the Current Population Survey tobacco supplements of 1995-1996 and 1998-1999 are presented. RESULTS: The percent of indoor workers working under a smoke-free policy increased slightly, from 62% in 1995-1996 to 65% in 1998-1999. Respondents with a college degree were more likely to work under a smoke-free policy than those with a high school education or less. Among respondents with a work policy in 1998-1999, a complete ban on smoking reduced any workplace exposure in the past 2 weeks (4%) compared to a partial ban (26%) or an unrestricted policy (30%). CONCLUSION: Wisconsin has seen a small increase in workplace policies that ban smoking in the workplace. These policies are more likely to protect workers of higher socioeconomic status and may increase health disparities in tobacco-related diseases in the future.

Adolescent↗

Forward for women's health: the state of women's health in Wisconsin.

Because of the magnitude of women's health issues within the larger context of public health and healthcare systems, this paper was written to help define the current status of women's health in Wisconsin. Utilizing critical women's health areas identified by the Wisconsin Women's Health Foundation and the Wisconsin Division of Public Health, 16 specific measures of women's health were chosen for this analysis. The most recent data available for each measure were collected with Wisconsin data being compared to national averages as well as to Healthy People 2010: Objectives for Improving Health targets. Wisconsin women fare better than national averages in nine of the selected health measures; however, there are still many improvements to be made in order to meet Healthy People 2010 targets. The areas where the most improvements are needed include binge drinking, tobacco use, diabetes, and stroke mortality. Other significant findings include the lack of uniformly collected data in the areas of domestic violence, osteoporosis, and mental illness.

Female↗

Wisconsin physicians advising smokers to quit: results from the Current Population Survey, 1998-1999 and Behavioral Risk Factor Surveillance System, 2000.

INTRODUCTION: Physicians advising their patients to quit smoking has been recognized as an effective component of smoking cessation treatment, yet evidence suggests that physicians are not consistently providing this type of counseling. METHODS: Data from both the Current Population Survey's (CPS) Tobacco Use Supplements administered September 1998, January 1999, and May 1999 and from the 2000 Behavioral Risk Factor Survey System (BRFSS) were analyzed and compared. The weighted proportions and 95% confidence intervals of Wisconsin and US smokers who had seen a physician in the past year and reported receiving advice from them to quit smoking were calculated. Proportions were analyzed for the total population as well as for subgroups of gender, age, race, educational level, and income level. RESULTS: CPS data showed that Wisconsin smokers who had seen a physician in the past year were significantly more likely to receive smoking cessation advice from their physician (64%) compared to US smokers (59%). Though not significant, a similar trend was seen in the BRFSS data. There were no consistent significant differences in rates analyzed by gender, age, race, educational level, or income level. CONCLUSIONS: Data from the CPS and BRFSS show that less than two thirds of Wisconsin smokers are receiving smoking cessation advice from their physicians. Increasing physician counseling of patients who smoke continues to be a priority public health goal for decreasing morbidity and mortality from tobacco-related illnesses.

Adult↗

Progress in reducing mortality among Wisconsin residents, 1980-2000: rates decline, but black-white disparities increase.

PURPOSE: To assess progress towards 2 overarching public health goals--improvement in length of life and reducing health disparities. METHODS: Age specific mortality rates in Wisconsin from 1980 to 2000 were obtained from the US Centers for Disease Control and Prevention WONDER database. Rates for each age group were gathered for the entire Wisconsin population and for black and white subgroups. Trends in mortality rates were plotted, change in mortality rates was estimated, and the number of "lives saved" annually from 1980-1984 to 1996-2000 was calculated. In addition, black vs white rate ratios were calculated at both the beginning and the end of the time period to determine trends in black-white mortality disparities. RESULTS: Mortality is decreasing in Wisconsin in every age group. The largest relative improvements in mortality rates occurred among infants <1 year (-30%), children 1-14 years (-27%), and adults 45-64 years (-23%). Comparatively little progress was seen among adults 25-44 years (-5%) and those 85 years and older (-0.5%). Black/white disparities increased in every age group. During 1996-2000, approximately 5000 fewer deaths occurred each year than expected based on mortality rates from 1980-1984. CONCLUSION: Despite progress towards increasing length of life, progress towards eliminating disparities was not seen over the 1980 to 2000 time period.

Black People↗

Assessing a decade of progress in cancer control.

The age-adjusted death rate from cancer peaked in the U.S. in 1990, and has declined steadily since then. We assess reasons for this progress by examining trends in cancer mortality by age, gender, and cause, using underlying cause mortality data from the Centers for Disease Control. Mortality rates for 2000 were estimated using models based on 1979 through 1997 mortality data. Indirect standardization was used to calculate the expected number of cancer deaths in 2000, by age, gender, and cause, assuming that the rates in 1990 had not changed. In the U.S. in 2000, there were an estimated 500,000 deaths from cancer; 64,000 (12.7%) fewer than expected, with 51,900 fewer cancer deaths among men and 12,200 fewer deaths among women. The decline in deaths among men resulted from fewer deaths from lung cancer (20,800), colon cancer (6,700), and prostate cancer (12,900). The decline in deaths among women resulted from fewer deaths from breast cancer (11,100) and colon cancer (4,200), but there were more deaths from lung cancer (6,500). Among women over the age of 75, 5,000 more died of cancer than expected. Declines in lung, prostate, and colon cancer deaths among men and breast and colon cancer among women account for 86% of the recent decline in cancer deaths over the past decade.

Adult↗

Mentorship and competencies for applied chronic disease epidemiology.

To understand the potential and establish a framework for mentoring as a method to develop professional competencies of state-level applied chronic disease epidemiologists, model mentorship programs were reviewed, specific competencies were identified, and competencies were then matched to essential public health services. Although few existing mentorship programs in public health were identified, common themes in other professional mentorship programs support the potential of mentoring as an effective means to develop capacity for applied chronic disease epidemiology. Proposed competencies for chronic disease epidemiologists in a mentorship program include planning, analysis, communication, basic public health, informatics and computer knowledge, and cultural diversity. Mentoring may constitute a viable strategy to build chronic disease epidemiology capacity, especially in public health agencies where resource and personnel system constraints limit opportunities to recruit and hire new staff.

Chronic Disease↗