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Biomedical subjects

Paul P Urbanski

Publications and source records attributed to Paul P Urbanski.

17 recordsLinked to original sources
PubMed2006

Carotid artery cannulation in aortic surgery.

OBJECTIVE: Carotid artery cannulation was initially established at our clinic for surgery of acute aortic dissection, and it became the standard approach for procedures in which circulatory arrest is necessary. The aim of the study was to evaluate this method's efficiency regarding postoperative outcomes after the first 100 procedures. METHODS: Between July 2002 and October 2005, 100 patients underwent aortic surgery using carotid artery cannulation by a side graft for arterial return with a mean flow rate of 4.6 +/- 0.5 L/min. There were 27 patients with acute and 2 with chronic type A aortic dissection. Sixteen patients had had prior cardiac surgery. During circulatory arrest, the arterial line was used for unilateral cerebral perfusion in moderate hypothermia (mean rectal temperature 28 degrees C +/- 1.6 degrees C) with a mean flow rate of 0.85 +/- 0.2 L/min. RESULTS: Carotid artery cannulation offered adequate arterial return in all patients. In no case was a switch to another cannulation site necessary for arterial return. Furthermore, no complications related to the cannulation site were observed. One patient with acute dissection and 1 with chronic aneurysm died during the early postoperative course. Thus, 30-day mortality was 2.0% for the whole group and 3.7% for the dissection group. Two patients with severe calcification of the aortic valve had strokes. There were no strokes in the dissection group, although there were preoperative signs of cerebral malperfusion in 4 patients. CONCLUSIONS: Carotid artery cannulation is a fast, safe, and efficient method of arterial cannulation even in very obese patients. In addition, it simplifies the procedure of unilateral cerebral perfusion through the arterial line during circulatory arrest, making it completely unnecessary to interrupt cerebral perfusion.

Adolescent↗
PubMed2005

Valve-sparing aortic root repair with patch technique.

BACKGROUND: In the valve-sparing aortic root repair technique presented, each pathologic sinus is replaced with a teardrop-shaped patch. In this study, the clinical and echocardiographic results after the first 20 procedures are evaluated. METHODS: Between September 2000 and May 2004, 20 patients underwent aortic root repair using a patch technique. Eight patients had an acute type A aortic dissection and 12 patients had an aneurysm of the ascending aorta. In 12 cases, the aortic root was reconstructed with three patches, in 1 case with two patches, and in 7 cases with one patch. RESULTS: The postoperative echocardiography at discharge showed no aortic regurgitation in 15 cases and trivial regurgitation in 5 cases. Three patients with aortic dissection as an initial pathologic diagnosis died during a median follow-up period of 14.5 months (range, 0.5 to 32 months). At the time of follow-up, the echocardiographic findings in all 17 survivors remained unchanged from the early postoperative examinations. Median peak and mean transvalvular gradients were 8 mm Hg (range, 3.2 to 14 mm Hg) and 4 mm Hg (range, 1.7 to 6 mm Hg), respectively. CONCLUSIONS: The technique presented allows an individualized reconstruction of the sinuses of Valsalva, a simplified sizing of the vascular graft, and the creation of a new sinotubular junction resulting in good hemodynamic conditions. The technique is especially advantageous in patients in whom replacement of all sinuses is not necessary.

Adult↗
PubMed2005

Femoral versus aortic cannulation for surgery of chronic ascending aortic aneurysm.

BACKGROUND: Femoral artery cannulation and retrograde arterial perfusion have been postulated to increase the risk of cerebral embolism. In this study, the impact of the arterial cannulation site on the perioperative results after proximal aortic surgery is evaluated. METHODS: Between January 1996 and December 2002, a total of 327 patients underwent proximal aortic repair for chronic non-dissected aortic disease. The arterial inflow was established by cannulation of the aortic arch (group A) or the femoral artery (group F) in 166 and 161 patients, respectively. RESULTS: The early 30-day mortality was 0.9% (3 patients [1 patient in group A and 2 patients in group F]). The overall rate of early focal neurologic dysfunction (permanent and transient) was 4% (13 patients) and there was no significant difference between the two groups (4.2% vs 3.7%). Due to an intraoperative injury of the arterial wall, there were 6 repairs (3.6%) of the aortic arch in group A and 1 repair (0.6%) of the femoral artery in group F. The univariable examination of preoperative and intraoperative variables demonstrated that hypertension and increased cholesterol level could be possible independent risk factors for neurologic morbidity. In the following stepwise logistic regression, only the preoperative hypercholesterolemia was identified as an independent predictor for postoperative focal neurologic dysfunction. CONCLUSIONS: The arterial inflow via the femoral artery and the subsequent retrograde perfusion during cardiopulmonary bypass do not increase the risk of neurologic complications in patients who undergo proximal aortic repair due to chronic non-dissected aortic aneurysm. Because there is an increased risk of aortic wall injury during cannulation, the femoral artery seems to be more suitable in these cases for cannulation than the proximal aorta.

Adult↗
PubMed2005

Modified versus standard mechanical valved aortic conduit.

The aim of this study was to compare the hemodynamic characteristics and early clinical results of a commercially available standard aortic conduit with those of a modified valved composite graft, which consists of a mechanical valve prosthesis sewn into a vascular tube and placed in a supraannular position. The modified conduit was placed in 40 patients (group 1) and the standard conduit in another 40 patients (group 2). The early postoperative mortality rates (within 30 days after surgery) were 0% in group 1 and 5% (2 patients) in group 2; the difference was not statistically significant. The mean geometric orifice area of the valve prosthesis was significantly larger in group 1 than in group 2 (3.7 +/- 0.7 cm(2) versus 2.9 +/- 0.5 cm(2)). Early results showed a hemodynamic advantage of the modified conduit, with significantly lower transvalvular gradients.

Adult↗
PubMed2004

Atresia of the right vertebral artery in a patient with acute aortic dissection.

A 49-year-old man had severe neurocognitive dysfunction after urgent operation for acute type A aortic dissection. Complete aortic arch replacement with single reimplantation of the arch branches was performed with the patient under deep hypothermic circulatory arrest. Retrospectively, my colleagues and I consider the atresia of the right vertebral artery to be responsible for this complication and discuss whether knowledge of the anomaly and adapting the operative strategy accordingly would have improved the neurologic outcome.

Aortic Dissection↗
PubMed2003

Valved stentless composite graft: clinical outcomes and hemodynamic characteristics.

BACKGROUND: The valved stentless composite graft has become well established in our hospital for replacement of the ascending aorta and aortic valve in elderly patients and those with contraindication for lifelong anticoagulation. This study was conducted to evaluate the postoperative hemodynamic characteristics and clinical outcomes after implantation of this device. METHODS: Between November 1998 and February 2001, 45 consecutive patients with a mean age of 69 years underwent implantation of a composite graft using a stentless valve prosthesis (Toronto SPV) incorporated in a collagen-coated Dacron tube (InterGard). The indication for surgery was aortic valve disease with an accompanying true aneurysm of the ascending aorta in 42 patients and a dissection of the aortic wall in 3 patients. Postoperative echocardiographic examinations were performed before discharge from the hospital and at the time of the follow-up. Mean follow-up duration was 18 months (range 3 to 30 months). RESULTS: There was no perioperative mortality. During follow-up, there were two noncardiac, nonvalve-related deaths. Echocardiographic evaluation before discharge and at follow-up demonstrated favorable hemodynamics of the valve prosthesis with mean transvalvular gradients of 8.5 +/- 2.9 mmHg and 8.0 +/- 3.1 mmHg, respectively. No regurgitation across the valve and no contact of the cusps with the Dacron tube were seen in any case. CONCLUSIONS: A stentless composite graft for replacement of the aortic valve and ascending aorta offers excellent hemodynamic results and is a suitable device for patients in whom anticoagulation should be avoided.

Adult↗
PubMed2003

Is extended aortic replacement in acute type A dissection justifiable?

BACKGROUND: The aim of this study was to evaluate the effectiveness of our surgical strategy for acute aortic dissection based on the extent of the dissection and the site of the entry, with special emphasis on resection of all dissected aortic segments if technically possible. METHODS: Between January 1995 and March 2001, 43 consecutive patients underwent operations for acute aortic dissection. In all patients the distal repair was performed under circulatory arrest without the use of an aortic cross-clamp. Fifteen patients underwent aortic arch replacement with additional reconstruction of supra-aortic vessels in 3 patients. Complete replacement of all dissected tissue could be achieved in 21 patients (group 1). Because of the distal extent of the dissection beyond the aortic arch, replacement of all the dissected tissue was not possible in 22 patients (group 2). RESULTS: Early mortality was 4.7% (2 patients), and the incidence of perioperative cerebrovascular events was 7.0% (3 patients). All of these events occurred in group 2 (p < 0.025). During the follow-up period of 6 years or less, 5 patients died, all from causes not related to the aorta or the aortic valve. A persisting patent false lumen was observed in 14 of the 36 surviving patients (39%). CONCLUSIONS: Extended replacement of the dissected ascending aorta and aortic arch can be done with good early and midterm results, even though it requires a complex surgical technique. Therefore we advocate complete replacement of the dissected parts of the aorta in all patients in whom this is technically possible.

Aged↗
PubMed2002

Complete aortic root replacement in patients with small aortic annulus.

BACKGROUND: We evaluated the effectiveness of our surgical method using a modified self-assembled valved composite graft in patients with a narrow aortic annulus. METHODS: Between August 2000 and May 2001, 10 consecutive patients with a narrow aortic annulus underwent replacement of the aortic valve and the ascending aorta using a valved composite graft with mechanical valve prosthesis. The indication for surgery was aneurysm of the ascending aorta (8 patients) and aortic dissection (2 patients). To avoid valve-patient mismatch, a modified self-assembled valved composite graft was used. RESULTS: There was no hospital mortality. Echocardiographic evaluation before discharge showed excellent hemodynamics with a mean transvalvular gradient of 10.7 mm Hg (standard deviation +/- 2.8 mm Hg). CONCLUSIONS: The described valved composite graft offers very good hemodynamic performance and is a simple and effective device to avoid valve-patient mismatch in patients with a small aortic annulus who need aortic root replacement.

Adult↗
PubMed2002

Stenosed kinking of the left main coronary artery combined with an aneurysm of the ascending aorta.

Stenosed kinking of the left main coronary artery is described in a 60-year-old man with an aneurysm of the ascending aorta and severe aortic valve insufficiency. An elective complete ascending aorta replacement using a valved composite graft was performed along with a shortening and direct implantation of the left main coronary artery. The right coronary artery was reimplanted as a Carrel-button.

Aortic Aneurysm↗
PubMed2002

When is total aortic arch replacement indicated in patients with acute aortic dissection?

BACKGROUND: The purpose of this preliminary study was to evaluate the effectiveness of our surgical strategy for acute aortic dissection with special emphasis on curative resection of the dissected segments of the aorta. MATERIAL/METHODS: Between January 1995 and April 1999, 29 patients underwent surgery for acute aortic dissection. In 16 patients (Group 1) the dissection was limited to the ascending aorta (8 patients - Group 1a) or involved the ascending aorta and the entire aortic arch (8 patients - Group 1b). Complete resection of all dissected aortic segments (ascending aorta or ascending aorta with complete aortic arch) was performed in these cases, extending to the healthy tissue border. 13 patients (Group 2) presented with dissection of the entire aorta). These patients underwent replacement of the proximal part only of the dissected aorta. RESULTS: Early mortality (within 30 days) and the incidence of perioperative cerebrovascular events was 3.4% and 10.3% respectively. These events all occurred in Group 2. During the follow-up period of up to six years, there were no significant differences between the surviving patients in regards to long-term mortality and morbidity, although a persisting patent false lumen was observed in seven patients from Group 2. CONCLUSIONS: Extension of ascending aorta replacement to include the complete aortic arch can be accomplished in patients amenable to complete resection of the dissected aorta without increasing operative risk and with good mid-term results. We believe that total aortic arch replacement is indicated in these cases.

Aged↗