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Biomedical subjects

Paweł Kolasa

Publications and source records attributed to Paweł Kolasa.

4 recordsLinked to original sources

Herpes simplex encephalitis: a case report.

BACKGROUND: Despite advances in antiviral therapy over the past 2 decades, herpes simplex encephalitis (HSE) remains a serious illness with significant risk of morbidity and death. HSE is the most common cause of sporadic viral encephalitis, with a predilection for the temporal lobes and a range of clinical presentations, from aseptic meningitis and fever to a severe rapidly progressive form involving altered consciousness. Clinical features of HSE include fever with mental status changes (depressed level of consciousness, confusion, disorientation, personality changes) sometimes with seizures (focal or generalized), dysphagia, or other focal neurological signs. Symptoms vary in intensity early in the disease, but tend to progress rapidly. CT and MRI can play an important role in determining the diagnosis and extent of the disease. CASE REPORT: This case report refers to a 17-year-old girl, previously diagnosed with herpes encephalitis, and presents the outcome of rehabilitation on the patient's mental state during a 7-year follow-up period. CONCLUSIONS: The prognosis for patients with HSE has been dramatically improved by the availability of specific antiviral therapy; sequelae in surviving patients may include severe neurological deficits, seizures, and/or neuropsychological dysfunctions that greatly impair quality of life. To improve the prognosis for patients with HSE, acyclovir treatment should be initiated as soon as HSE is suspected. After discharge, rehabilitation should be provided, in the effort to improve the patient's self-reliance in everyday life.

Adolescent↗

Coexistence of diffuse large B-cell lymphoma within pontocerebellar angle schwannoma.

We present an unusual case of diffuse large B-cell lymphoma within pontocerebellar angle schwannoma in 62-year-old woman. The patient suffered for 5 months with V, VII and VIII nerves paresis and with cerebellar ataxia. CT scan demonstrated large hyperdensive mass in cerebellopontine angle translocating cerebellar hemisphere and cerebral trunk. The patient was subjected to surgery and the tumour was removed totally by suboccipital retromastoidal right craniectomy approach. Histopathological examination revealed schwannoma infiltrated with high grade B-cell lymphoma. The patient did well following surgery without any other lymphoma manifestations, and she died from a heart attack 20 months later. Solitary lymphoma of pontocerebellar angle coexisting with schwannoma is an unusual finding, thus our case is the first report.

Brain Stem Neoplasms↗

[Embolization of supratentorial angiomas. Own experience].

UNLABELLED: Embolization of intracerebral angiomas has been performed in our Center since 1995. Main criteria for the treatment include bleeding into the central nervous system (CNS), epilepsy, and other neurological symptoms. METHOD: CNS angiography and angioma location were performed using the Seldinger technique. A highly selective microcatheterization of particular angioma feeders was carried out then in the DVM system. After a radiological confirmation of the precise location of the catheter end in the angioma, embolization of the angioma feeders and nidus was performed with the Histoacryl-Lipiodol mixture. RESULTS: One hundred endovascular treatment procedures were performed in 58 patients with cerebral angiomas of IV and V grade according to the Spetzler-Martin scale. The total angioma occlusion was attained in 35 patients (63.3%), and partial--in 18 (31.8%) cases. There were four early deaths (6.8%) and one late (1.8%), not related to the surgical procedure. CONCLUSION: Embolization is a new and effective method of treatment of extensive supratentorial angiomas.

Adolescent↗

[Combined treatment of cerebral aneurysm and angioma. A case report].

The paper presents a case of co-existent cerebral aneurysm and angioma, as well as the treatment method used. Although in the authors' Center over 600 patients were submitted to aneurysm surgery and in about 250 cases endovascular procedures were performed during the past decade, it is for the first time that the co-existence of both aneurysm and angioma has been found. Successive stages of the diagnostic process, therapeutic procedures in the order of their application, as well as the treatment outcome are discussed. "Combined" treatment including both microsurgery and endovascular techniques can be regarded as effective in the treatment of mixed vascular malformations in the brain, making a full recovery possible.

Adult↗