Biomedical subjects

Paweł Rybojad

Publications and source records attributed to Paweł Rybojad.

4 recordsLinked to original sources

PubMed2003

[Microflora colonizing pleural drains after thoracic surgery].

The aim of this paper was to analyse aerobic and anaerobic bacterial flora colonizing pleural drains in 32 patients with lung tumor undergoing pulmonary resection and receiving antimicrobial prophylaxis. Fluid from pleural drains was taken up on the day of operation and on the 3-rd or 4-th day after the operation. Significant number of aerobic bacteria, mainly methicillin-resistant coagulase-negative staphylococci and multidrug resistant Gram-negative rods, were isolated from 30 (46.9%) specimens. Lower number of anaerobic bacteria were found in 24 (37.5%) specimens. Colonization of the pleural drains does not mean infection, (in only one patient isolated Pseudomonas aeruginosa could be the etiologic agent of infection) however knowledge about bacterial species found in drain fluid in a local population and drug susceptibility of isolated strains allows to propose effective antimicrobial prophylaxis.

Adult↗

PubMed2003

[Phenotypic characteristics of coagulase-negative Staphylococci colonizing pleural drains in patients with lung cancer after thoracic surgery].

Coagulase-negative staphylococci (CNS) represent an important group of etiologic agents of infections associated with plastic biomaterials, e.g. drains. In the present paper 33 strains of CNS were characterized. All of them were isolated from fluid of pleural drains in patients with lung cancer after pulmonary resection under conditions of antimicrobial prophylaxis. The most frequently isolated species were Staphylococcus epidermidis and S. warneri. The majority of CNS strains showed ability to produce slime and possessed hydrophobic properties of cell surface. Strains of CNS resistant to penicillin and oxacillin, but sensitive to amoxicillin/clavulanate were isolated most frequently. Only two methicillin-resistant strains, belonging to S. haemolyticus, were found. The obtained data indicate that CNS strains colonizing pleural drains had potential ability to adhere to smooth surfaces. Most of isolated strains were susceptible to antibiotics and chemotherapeutics routinely used in staphylococcal infections.

Anti-Infective Agents↗

PubMed2003

Surgical treatment of severe emphysema--analysis of own material.

UNLABELLED: The aim of the study was a retrospective analysis of effectiveness of surgical treatment of severe diffuse emphysema, including urgent cases with symptomatic pneumothorax. We analyzed 99 patients with severe diffuse emphysema who underwent surgical treatment in Department of Thoracic Surgery in Lublin between 1995 and 2001. The evaluated group consisted of 86 men and 13 women aged from 27 to 83 (mean age 56.6). Among them 54 were operated on due to sudden pneumothorax, which was a result of bursted emphysematous parenchyma. Those patients were not evaluated with spirometry and CT of the chest. All the other patients were carefully examined and qualified for surgical treatment according to precise criteria: presence of clinical and radiological symptoms of diffuse severe emphysema (DSE), FEV1<35%, pCO2>50mmHg. Those 43 patients eligible for Lung Volume Reduction Surgery iLVRS) also did not have any main contraindications for lung surgery. In the whole analyzed population 89 resections were unilateral, limited to 20-25% of the most destroyed tissue. In 10 cases operation was bilateral, among them four were simultaneous and the remaining six were not. In our study we evaluated the frequency and degree of complications, early results of treatment, influence of surgery on selected parameters: FEV1, pCO2, subjective dyspnea according to Medical Research Council Dyspnea Scale. We observed three perioperative deaths. The most common complications were air leak> five days, cardiopulmonary insufficiency, pneumonia. Early results showed subjective decrease of dyspnea and in most cases improvement of the analyzed parameters. CONCLUSIONS: The early results are optimistic and correspond to the observations of other authors. Further analysis of the collected data and long term results will allow establishing the role of LVRS in treatment of Diffuse Severe Emphysema.

Adult↗

PubMed2003

Preoperative chemotherapy as a predisposing factor for colonization of upper respiratory tract with Candida spp. in patients with non-small cell lung cancer.

In the present study 48 patients with non-small cell lung cancer (NSCLC) were included--20 patients from control group and 28 patients after at least one course of preoperative chemotherapy. The analysis of nasopharyngeal microflora in these patients suggests that preoperative chemotherapy can be regarded as a predisposing factor for colonization of mucous membrane of throat with yeast-like fungi--Candida spp.

Adult↗