Smoking habits, nicotine use, and congenital malformations.
Explore the source record for details and available documents.
Congenital Abnormalities↗
Biomedical subjects
Peter Davidson
Publications and source records attributed to Peter Davidson.
Commercial sex work and risk of HIV infection among young drug-injecting men who have sex with men in San Francisco.
OBJECTIVE: The objective of this study was to investigate the relationship between sex work and HIV infection among young injection drug-using men who have sex with men (MSM-IDU). STUDY DESIGN: This study was a cross-sectional analysis of behavioral and serologic data collected from 227 street-recruited MSM-IDU in San Francisco, California, between January 2000 and November 2001. RESULTS: Sixty-eight percent of participants reported being paid by another man for sex. HIV prevalence was 12% (95% confidence interval, 8-16%); 42% of seropositive participants were unaware of their infection. HIV was independently associated with higher number of paying male partners and history of gonorrhea and inversely associated with number of female partners, education, and syringe-sharing. Consistent condom use overall was 41%, but varied significantly by type of partner. CONCLUSIONS: Among MSM-IDU in San Francisco, sex work with men is strongly associated with HIV infection and the prevalence of condom use is low. HIV prevention among MSM-IDU must be tailored to address the excess risk associated with sex work.
Adolescent↗
Rhabdomyolysis following laparoscopic radical nephrectomy: a case to heighten awareness.
Rhabdomyolysis, myoglobinuria and acute renal failure are rare complication of surgery. Long operative time, increased body mass, lateral decubitus positioning and extracellular volume depletion may predispose to this condition. The authors describe the case of a 70-year-old man with renal cell carcinoma who underwent a laparoscopic right radical nephrectomy in the lateral decubitus position. His postoperative course was complicated by acute renal failure due to rhabdomyolysis. Heightened awareness, early recognition and treatment of this condition are important, particularly as laparoscopic nephrectomy is becoming a common procedure for living donor transplantation.
Aged↗
Leaching of copper, chromium and arsenic from treated vineyard posts in Marlborough, New Zealand.
There have been conflicting reports as to the extent that copper-chromium-arsenic (CCA) treatments leach from timber. In New Zealand, vineyards utilise CCA-treated posts at a rate of 579 posts per hectare. This represents a potential CCA burden on the soil of 12, 21, and 17 kg/ha, respectively, for the three elements. Given a replacement rate of 4% per year, the use of CCA-treated posts may result in an accumulation of these elements in the soil, possibly leading to groundwater contamination. We undertook a general survey to determine the extent of CCA leaching from treated vineyard posts. Treated Pinus radiata posts were sampled at six sites around the Marlborough region of New Zealand to represent a range of post ages and soil types. For each post, above- and belowground wood samples were taken. As well, the soil adjacent to the post was sampled at a 50 mm horizontal and 100 mm vertical distances from the post. The belowground wood samples of the posts had significantly lower CCA concentrations than the aboveground portions, which were not significantly different from new posts. This indicates leaching. Soils surrounding the posts had significantly higher CCA concentrations than control soils. Higher CCA concentrations were measured under the posts than laterally. Some 25% of the samples exceeded 100 mg/kg As, the Australian National Environment Protection Council (ANEPC) guideline level for As in agricultural soil, and 10% exceeded 100 mg/kg Cr, the ANEPC limit for chromium. At one site, we found a significant positive correlation between post age and CCA-leaching. The CCA issue could be eliminated by using alternative posts, such as steel, concrete, or untreated woods such as Eucalyptus or beech. Alternatively, CCA-treated posts could, for example, be lacquered or otherwise protected, to reduce the rate of CCA leaching.
Agriculture↗
Growth hormone replacement in adults and bone mineral density: a systematic review and meta-analysis.
BACKGROUND: The effect of GH replacement on bone mineral density (BMD) in adults with GH deficiency (GHD) is uncertain. We carried out a systematic review of randomized trials that compared GH to no active treatment, with BMD as an outcome. METHODS: We searched electronic databases to identify articles, abstracts and conference proceedings to March 2002. We also checked reference lists in included studies and expert reviews. Two reviewers independently extracted the data on study design and change in BMD. The results of individual trials were combined by fixed effects model meta-analysis using weighted mean difference (WMD) of change in BMD at the lumbar spine (our primary outcome) and other sites. FINDINGS: Eighteen trials that included 700 patients met the inclusion criteria. Maximum follow-up was for 12 weeks (1 trial), 6 months (14 trials), 12 months (1 trial), 18 months (1 trial) and 24 months (1 trial). Reporting quality of both study design and results was poor. Ten trials (458 subjects) were included in the meta-analysis. We excluded those eight trials from which sufficient data could not be extracted. We found a mean change in BMD, at the lumbar spine with GH treatment, of 0.01 g/cm2 after 6 and 12 months, 0.02 g/cm2 after 18 months and 0.03 g/cm2 after 24 months. Statistical significance at the 0.05 level was just achieved at 6 and 12 months but was significant at 18 and 24 months. These changes are small and may be influenced by bias. CONCLUSION: There is evidence of a small effect of GH replacement on bone mineral density in adults with GH deficiency. The clinical importance of this is uncertain.
Adult↗
Screening for prostate cancer.
Explore the source record for details and available documents.
Age Factors↗
A laser-aligned method for anthropometry of hands.
We have developed a laser-aligned measuring device to facilitate the measurement of linear hand dimensions. Our objective has been to make a simple, clinically applicable device for anthropometry of the hands in patients with arthritis in order to gauge the progression of hand deformities. The system provides an alternative to the use of rules, tapes, photogrammetry and least-squares devices which have previously been applied to hand measurements. The system delivers results which are not significantly different from those measured with rules and callipers and has a similar level of accuracy. The use of laser pointers for alignment facilitates measurements which necessitate picking the highest point of the hand. The device is portable and simple to use in the clinic. We have used it to measure hand dimensions in normal subjects and patients with arthritis. However, the system could equally well be used to facilitate measurement of other objects with an irregular surface profile.
Adult↗