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Biomedical subjects

Peter J Taub

Publications and source records attributed to Peter J Taub.

9 recordsLinked to original sources

Monobloc advancement by distraction osteogenesis decreases morbidity and relapse.

BACKGROUND: Treatment of midface hypoplasia and forehead retrusion with monobloc advancement is associated with significant complications, including meningitis, prolonged intubation, and frontal bone flap necrosis. To see whether distraction of the monobloc segment offered decreased morbidity, the authors compared clinical outcomes of patients who underwent conventional monobloc advancement with those of patients who underwent monobloc distraction. METHODS: Group 1 (conventional monobloc; n = 12) underwent traditional monobloc advancement with bone grafting. Group 2 (modified monobloc; n = 11) did not receive ventriculoperitoneal shunts and underwent the above procedures with placement of a pericranial flap and fibrin glue over the midline defect. Group 3 (monobloc distraction; n = 24) underwent advancement of the monobloc segment by distraction osteogenesis using internal distraction devices. Complications included meningitis, cerebrospinal fluid leak, frontal bone flap loss, and wound infection. Preoperative, postoperative, and follow-up lateral cephalograms were used to assess horizontal changes of the forehead, midface, and maxilla. RESULTS: Group 3 (distraction monobloc) had the lowest complication rate (8 percent), followed by groups 2 (modified monobloc; 43 percent) and 1 (conventional monobloc; 61 percent) (p < 0.05). Group 3 achieved greater advancement (12.6 mm) than did group 2 (9.4 mm) or group 1 (9.1 mm) (p < 0.05). Relapse was least in group 3 (8 percent) compared with groups 2 (67 percent) and 1 (45 percent). CONCLUSIONS: Monobloc advancement by distraction osteogenesis had less morbidity and achieved greater advancement with less relapse compared with conventional methods of acute monobloc advancement with bone grafting. Monobloc distraction is superior to conventional methods of acute monobloc advancement and is an alternative to staged fronto-orbital advancement followed by Le Fort III advancement.

Adolescent↗

Hyoid bone fractures.

Surgeons who manage patients with craniofacial trauma should be comfortable with evaluating and treating fractures throughout the head and neck. This includes the hyoid bone, which may cause significant airway concerns if fractured. The authors report the case of a patient who sustained a fracture of the hyoid bone. The hospital records from a busy, level I trauma center were reviewed to document similar injuries over a seven-year period. To supplement the scant literature concerning hyoid fractures, a review of the anatomy, diagnosis, and management of such injuries is provided.

Accidents, Traffic↗

Orbital dystopia managed with unilateral brow suspension.

Patients with orbital dystopia present with symptoms of diplopia and/or facial asymmetry. Repositioning of the orbit requires multiple osteotomies around the orbit, which presents significant complications. The authors present an alternative method to restore facial symmetry in the case of a 14-year-old patient with congenital orbital dystopia due to fibrosis of the sternocleidomastoid muscle. The patient had no ocular symptoms but did have asymmetric descent of the ipsilateral brow. He refused box osteotomy and repositioning of the orbit. Unilateral brow suspension was performed using an endoscopic technique and suspension sutures fixed to resorbable screws. Adequate brow elevation was noted in the immediate postoperative period and at 6 months; it successfully restored facial symmetry.

Adolescent↗

Sequential second free bone flaps for reconstruction of metachronous mandibular defects.

BACKGROUND: The purpose of this study was to identify patients who had previously undergone composite resection of a primary carcinoma of the oral cavity and immediate mandibular reconstruction with an osteocutaneous free flap and subsequently developed a local recurrence or a second metachronous tumor that required a second composite resection and immediate mandibular reconstruction with a second osteocutaneous free flap, in order to evaluate bone-to-bone healing of the two vascularized bone grafts and the long-term survival of these patients. METHODS: Five patients who had undergone composite resection of a primary carcinoma of the oral cavity subsequently developed a local recurrence or a second metachronous tumor and therefore underwent mandibular reconstruction with two sequential osteocutaneous free flaps. Two sequential fibular osteocutaneous flaps were performed in three patients, two sequential radial forearm osteocutaneous flaps in one patient, and a scapular osteocutaneous flap followed by a radial forearm osteocutaneous flap in one patient. End-to-end osteosynthesis of the second free vascularized bone graft to the first free vascularized bone graft was achieved using mandibular reconstruction plates, miniplates, or compression screws. RESULTS: All five patients achieved solid bone-to-bone healing of the second free vascularized bone graft to the first free vascularized graft. Despite two patients only surviving 4 months after the second mandibular reconstruction, one patient survived for 1 year and 8 months and two patients remain disease-free after more than 3 years. CONCLUSION: Stable bone-to-bone union of a second osteocutaneous free flap to a previous osteocutaneous free flap mandibular reconstruction improves the quality of life of those patients who require a second composite mandibular resection for the treatment of a local recurrence or a metachronous tumor, but it is probably only palliative.

Adult↗

Mandibular distraction in a neonate with muscular dystrophy.

The following case report describes the successful use of distraction osteogenesis (DO) for the treatment of hypoplasia of the mandible in a patient with muscular dystrophy (MD). While DO has been used for hypoplasia of the mandible, no evidence exists that is it safe in the setting of MD. MD is a disease that primarily affects skeletal muscle; however, pathologic changes in the adjacent bone have been described. Furthermore, the healing of involved bone may be problematic, making DO a potentially unsuccessful technique in this group of patients. This report is the first successful utilization of DO for the treatment of mandibular hypoplasia in a patient with MD.

Female↗

Revisiting vascularized muscle flaps for complicated sternal wounds in children.

Surgeons at our center previously reported a case of a 2-month-old infant who underwent closure of an infected sternal wound following open cardiac surgery with debridement followed by closure with bilateral pectoralis muscle flaps and a unilateral rectus abdominis muscle flap. The success of the procedure has spawned refinements in the technique, such as the one described herein. A 2-week-old neonate was evaluated for postoperative sternal dehiscence and instability following open cardiac surgery for severe congenital cardiac anomalies. Management included initial debridement and application of a vacuum-assisted closure (V.A.C.) system (KCI, Oxfordshire, UK). In conjunction with the final V.A.C. dressing change, the patient underwent delay of the left rectus muscle by division of the inferior epigastric pedicle. She subsequently underwent transposition of the left rectus muscle and application of a full-thickness skin graft for coverage of the sternal defect. She has since done well and still requires further invasive cardiac procedures.

Cardiac Surgical Procedures↗

Typical facial clefting and constriction band anomalies: an unusual association in three unrelated patients.

The amniotic band sequence is a rare congenital condition in which it is hypothesized that fibrous band of amniotic tissue result in variable soft tissue derangements. Other terms that have been used to describe this condition are amniotic band syndrome and amnion rupture sequence. Patients may present with craniofacial, thoracic, abdominal, and/or limb involvement. Previous reports have described the association between the amniotic band sequence and unusual patterns of facial clefting, as described by Tessier, that do not follow normal embryonic lines of fusion [Keller et al., 1978; Bagatin et al., 1997]. We describe three successive cases of the amniotic band sequence, which presented with rather typical facial clefts (cleft lip and palate) in unrelated patients.

Abnormalities, Multiple↗