Biomedical subjects

Peter Konig

Publications and source records attributed to Peter Konig.

3 recordsLinked to original sources

PubMed2006

Building a subset of ICNP terms for oncological patients.

The present project was undertaken applying ICNP to internistic-oncological patients. This project investigated the coverage of this patient group by mapping terminology used in practice with ICNP. The specific aim was to build a subset of ICNP terms for oncological patients that can be used as a basic data catalogue for computerised nursing documentation. Furthermore the mappings, quality of match, and experiences of mapping was evaluated to discuss the domain completeness and utility of the ICNP in depicting the typical situation of oncological patients. The finding of this study will be submitted to the ICNP Review Process. The results can contribute to extending the ICNP content. The new ICNP statements will provide a beginning of an ICNP catalogue for cancer care.

Germany↗

PubMed2003

Responses to natural scenes in cat V1.

Studies on processing in primary visual areas often use artificial stimuli such as bars or gratings. As a result, little is known about the properties of activity patterns for the natural stimuli processed by the visual system on a daily basis. Furthermore, in the cat, a well-studied model system for visual processing, most results are obtained from anesthetized subjects and little is known about neuronal activations in the alert animal. Addressing these issues, we measure local field potentials (lfp) and multiunit spikes in the primary visual cortex of awake cats. We compare changes in the lfp power spectra and multiunit firing rates for natural movies, movies with modified spatio-temporal correlations as well as gratings. The activity patterns elicited by drifting gratings are qualitatively and quantitatively different from those elicited by natural stimuli and this difference arises from both spatial as well as temporal properties of the stimuli. Furthermore, both local field potentials and multiunit firing rates are most sensitive to the second-order statistics of the stimuli and not to their higher-order properties. Finally, responses to natural movies show a large variability over time because of activity fluctuations induced by rapid stimulus motion. We show that these fluctuations are not dependent on the detailed spatial properties of the stimuli but depend on their temporal jitter. These fluctuations are important characteristics of visual activity under natural conditions and impose limitations on the readout of possible differences in mean activity levels.

Action Potentials↗

PubMed2002

Invariant representations of visual patterns in a temporal population code.

Mammalian visual systems are characterized by their ability to recognize stimuli invariant to various transformations. Here, we investigate the hypothesis that this ability is achieved by the temporal encoding of visual stimuli. By using a model of a cortical network, we show that this encoding is invariant to several transformations and robust with respect to stimulus variability. Furthermore, we show that the proposed model provides a rapid encoding, in accordance with recent physiological results. Taking into account properties of primary visual cortex, the application of the encoding scheme to an enhanced network demonstrates favorable scaling and high performance in a task humans excel at.

Animals↗