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Biomedical subjects

Ph Pernot

Publications and source records attributed to Ph Pernot.

3 recordsLinked to original sources

[Melanotic schwannoma, a tumor with a unpredictable prognosis: case report and review of the literature].

A large sporadic melanotic schwannoma was found at the C2-C3 level in a 66-year-old woman who presented a pyramidal syndrome of all four limbs. The diagnosis was established by histology and immunohistochemical studies and confirmed by ultrastructural examination. Thirty-six cases of melanotic schwannoma located in the spinal cord have been reported in the literature, allowing an analysis of the different histological, clinical, and therapeutic aspects. Usually considered as benign tumor, melanotic schwannoma can recur and progress to malignancy, requiring long-term follow-up, specially in patients with multiple tumors and/or Carney's syndrome.

Aged↗

[Primary dural lymphoma. A case report].

Primary central nervous system lymphoma is an invasive disease in both HIV-positive and HIV-negative patients. Atypical presentations, including leptomeningeal involvement often described in cases with aggressive histology, have been reported but primary meningeal B-cell lymphoma appears to be very rare. A 40-year-old immunocompetent man developed a voluminous frontoparietal cranial vault tumor. The neurology examination demonstrated a large extra-axial mass involving the anterior part of the superior longitudinal sinus. The tumor extended through the cranial vault, without osteolysis, and grew in the subcutaneous tissue. Craniotomy was performed and the entire mass was resected without neurological deterioration. Pathology reported B-cell lymphoma. No other localization was found. Primary B-cell meningeal lymphoma, as illustrated in this case, can be another atypical presentation of CNS lymphoma.

Brain Neoplasms↗