Biomedical subjects

Phillip S Stacey

Publications and source records attributed to Phillip S Stacey.

2 recordsLinked to original sources

PubMed2004

Preliminary investigation of thiamine and alcohol intake in clinical and healthy samples.

Insufficient thiamine intake during heavy alcohol dependence has been well established as a precursor to alcohol-related brain damage, including Wernicke-Korsakoff syndrome. This study compared the alcohol and thiamine intakes of 35 alcohol-dependent patients upon admission for detoxification with 49 healthy young undergraduates. Subjects were interviewed using a retrospective diary that recorded alcohol and food and vitamin consumption for the previous seven days. As predicted, the clinical group consumed significantly less thiamine than the healthy group, and well below the minimum safe daily intakes. Findings have implications for the prevention of alcohol-related brain damage and public health policy.

Adult↗

PubMedDate not supplied

Detecting thiamine in beer.

AIMS: To ascertain whether thiamine HCl could be detected in beer using a double-blind triangular taste test. METHODS: Three 100 ml samples of beer to which 10 or 0 mg of thiamine were added were presented in counterbalanced order to 49 volunteers. Subjects consumed and rated each sample separately for taste and appearance and chose which beer was different. RESULTS: Thiamine-enriched beer could not be reliably distinguished from normal beer. However, a significant perceptual taste difference was found, with participants rating thiamine-fortified beer as more bitter than normal beer. CONCLUSIONS: Thiamine was found to alter the perception of bitterness of beer, but thiamine-fortified beer could not be reliably distinguished from normal beer.

Adolescent↗