PubMed Health⌕ Search

Biomedical subjects

Ping Song

Publications and source records attributed to Ping Song.

39 records · Page 3Linked to original sources
PubMed2002

Interleukin-2-induced antinociception in morphine-insensitive rats.

AIM: To investigate interleukin-2-induced antinociception in morphine-insensitive rats. METHODS: Paw withdrawal latencies (PWL) to noxious radiant heat were taken as the measurement of pain threshold. RESULTS: Intraplantar injection of human recombinant interleukin-2 (1.5 x10(4) U) significantly increased PWL in normal rats. PWL was also markedly increased by IL-2 in 45-d-post-complete Freund's adjuvant (CFA)-treated rats, which have been proven morphine-insensitive. IL-2-induced antinociception in CFA-treated rats were significantly lower than that in normal rats. IL-2-induced antinociception was partially blocked by naloxone (1 mg/kg, ip) in normal rats but remained unchanged in CFA group. CONCLUSION: IL-2-induced antinociception is partially mediated by mu-opioid receptors. Therapeutic applications of IL-2 may also be expanded to relieve morphine-insensitive pain.

Analgesics↗
PubMedDate not supplied

Polymerase chain reaction technology as analytical tool in agricultural biotechnology.

The agricultural biotechnology industry applies polymerase chain reaction (PCR) technology at numerous points in product development. Commodity and food companies as well as third-party diagnostic testing companies also rely on PCR technology for a number of purposes. The primary use of the technology is to verify the presence or absence of genetically modified (GM) material in a product or to quantify the amount of GM material present in a product. This article describes the fundamental elements of PCR analysis and its application to the testing of grains. The document highlights the many areas to which attention must be paid in order to produce reliable test results. These include sample preparation, method validation, choice of appropriate reference materials, and biological and instrumental sources of error. The article also discusses issues related to the analysis of different matrixes and the effect they may have on the accuracy of the PCR analytical results.

Agriculture↗