PubMed Health⌕ Search

Biomedical subjects

Poh Sun Goh

Publications and source records attributed to Poh Sun Goh.

4 recordsLinked to original sources

Use of D-dimer and lower extremity Doppler ultrasound results to obviate the need for computerised tomographic pulmonary angiography.

UNLABELLED: We hypothesise that correct interpretation of other diagnostic tests could reduce the use of computerised tomographic pulmonary angiogram (CTPA) examinations in patients with suspected pulmonary embolism (PE). MATERIALS AND METHODS: We carried out a retrospective analysis of 158 patients in a 928-bed university hospital. These consecutive patients were investigated for suspected PE from May 2001 to February 2002 using CTPA. RESULTS: There were 74 men and 84 women with a mean (+/-SD) age of 57 (+/-19) years. Overall, 56% of patients (89/158) showed clinically significant abnormalities on the CTPA examination. The overall prevalence of PE was 15% (24/158). The D-dimers were assayed in 40% (63/158) and lower limbs were scanned with Doppler ultrasound (US) in 22% (35/158) of patients. None of the 19 patients with negative D-dimer assays had PE. Of the patients who were positively tested on Doppler US, 4 were positive and 1 was negative for PE on the CTPA. None of the patients with positive Doppler US had negative D-dimer test. In retrospect, patient management based on negative D-dimer assays and positive lower extremity Doppler US studies could have reduced the need for further investigation with CTPA by 15% (24/158). CONCLUSION: In patients with suspected PE, correct interpretation of D-dimer and leg Doppler US tests may reduce the demand for CTPAs.

Adult↗

Tear flow dynamics in the human nasolacrimal ducts--a pilot study using dynamic magnetic resonance imaging.

BACKGROUND: Jones's theory of tear drainage suggests that the lacrimal sac fills when the eyelids are closed and empties into the nasolacrimal duct when the eyelids are open. This is aided by the contraction of the orbicularis muscle during each blink. This study was undertaken to ascertain the possibility of seeing the dynamic movement of tears in the nasolacrimal system during blinks using magnetic resonance dacryocystography (MR-DCG). METHODS: The sac was initially localized with a three-plane gradient echo sequence using a 1.5-T MRI platform. Fast, dynamic MR-DCG was carried out after we had instilled topically balanced salt solution (BSS) in five subjects and 0.5% gadolinium in seven subjects. The volunteers were asked to close and open their eyes during the fast imaging. The images were digitized to enable us to see the actual movement of fluid in the system. RESULTS: The tear movement was clearly seen as a bolus in the volunteers where BSS was used. The fluid passed into the nasolacrimal duct after several blinks when patent. The sac was never seen to empty completely. Though differential filling was seen between the upper and lower part of the sac, it was difficult to see the actual fluid movement in the volunteers when topical gadolinium was used. CONCLUSION: The findings of the study are supportive of the notion of fluid travel in the form of a bolus through the sac. Once a threshold volume is reached in the lower end of the sac, the fluid is seen to pass through the nasolacrimal duct. This happens after several blinks.

Acetates↗

Duodenal trauma.

Explore the source record for details and available documents.

Accidents, Traffic↗