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Praveen V Mummaneni

Publications and source records attributed to Praveen V Mummaneni.

At least 19 recordsLinked to original sources
PubMed2007

Combined ventral and dorsal surgery for myelopathy and myeloradiculopathy.

The past decade has witnessed significant advances in the surgical treatment of cervical myelopathy and myeloradiculopathy. In this article, we discuss in detail the indications for combined ventral and dorsal surgery for the treatment of cervical myelopathy and myeloradiculopathy. In addition, the advances in surgical technique and instrumentation in cervical spine surgery are explored. Finally, complication avoidance and management strategies are discussed. Combined ventral and dorsal decompression, reconstruction, and instrumentation procedures are viable options in the treatment of a select group of patients with complex cervical myelopathy or myeloradiculopathy.

Decompression, Surgical↗
PubMed2007

The decision-making process: allograft versus autograft.

The decision whether to use allograft or autograft in ventral cervical fusions has been widely discussed. The literature includes several prospective randomized trials. Extensive clinical evidence indicates that autograft use results in increased arthrodesis rates and less graft collapse. However, autograft harvest has a substantial morbidity rate. Allografts avoid the morbidity associated with autograft harvest but result in decreased arthrodesis rates and increased graft collapse rates. The decreased arthrodesis rate associated with allografts becomes more significant in multilevel surgery and in patients who smoke. The introduction and use of ventral cervical plates have made allograft use more attractive by increasing arthrodesis rates and decreasing graft collapse.

Bone Transplantation↗
PubMed2006

Cervicothoracic kyphosis.

Cervicothoracic kyphotic deformity may inhibit horizontal gaze function, impede activities of daily living, and induce disabling pain. Eventually, some patients develop a chin-on-chest deformity that limits their ability to eat and drink; in the end stage, a few patients also may have difficulty breathing. Progressive kyphosis can stretch the spinal cord leading to myelopathy with progressive lower extremity spasticity and weakness. Indications for surgery include myelopathy, pain, dysphagia or dyspnea owing to kyphosis, and difficulty maintaining a functional horizontal gaze. Patients with unstable cervicothoracic fractures also require surgical fixation. For these patients, surgical goals include deformity correction with restoration of an acceptable forward gaze, re-establishment of sagittal balance, decompression of the spinal cord (if myelopathic), and stable fixation.

Cervical Vertebrae↗
PubMed2006

Recurrent subdural hematoma caused by cerebrospinal fluid leakage. Case report.

The authors report a case of a recurrent subdural hematoma (SDH) that was caused by a persistent cerebrospinal fluid (CSF) leak from an L1-2 fistula. A 34-year-old man experienced severe headaches due to SDH, and he underwent aspiration of subdural fluid four times due to recurrent collections. Further evaluation with computerized tomography (CT) myelography demonstrated extradural extravasation of contrast through an L1-2 fistula. The patient underwent an L1-2 laminectomy; a small dural defect with CSF leakage at the left nerve root sleeve was found and was repaired. Following the repair, the patient had no further recurrence of SDH. Recurrent SDH, caused by spontaneous CSF leakage through a lumbar CSF fistula, is extremely rare. In cases of recurrent SDH, radiographic workup with spinal CT myelography should be considered.

Adult↗
PubMed2006

Infected vertebroplasty requiring 360 degrees spinal reconstruction: long-term follow-up review. Report of two cases.

Transpedicular vertebroplasty has been established as a safe and effective treatment of thoracic and lumbar compression fractures. Complications are rare, and infectious complications requiring surgical management have only been reported once in the literature. The authors present two cases of infectious complications requiring surgical management. They emphasize that systemic infection is a contraindication to the performance of vertebroplasty. The serious nature of these infections, their surgical management, and strategies for avoiding them are discussed.

Enterobacteriaceae Infections↗
PubMed2005

Current treatment strategies for the painful lumbar motion segment: posterolateral fusion versus interbody fusion.

STUDY DESIGN: Review of the literature. OBJECTIVES: We discuss the indications and contraindications for posterolateral lumbar fusion and posterior approaches to lumbar interbody fusion. We also review the advances in minimal access surgical techniques, graft materials, and osteobiologics. SUMMARY OF BACKGROUND DATA: Previously published data and our own surgical experience form the basis of this report. METHODS: A Pub Med online internet search for the keywords was performed. The pertinent articles were then cited. RESULTS: Posterior interbody fusion techniques have theoretical and demonstrable advantages over posterolateral fusion, but the former is also associated with greater morbidity. There are several approaches one may use to perform posterior interbody fusion, as well as multiple minimally invasive techniques and interbody spacer graft options. Bone morphogenetic protein offers an attractive alternative for achieving fusion. CONCLUSION: Fusion of painful motion segments is widely used to treat patients with degenerative low back pain. Successful arthrodesis may be achieved using either posterolateral fusion with pedicle screw fixation or posterior interbody fusion, depending on the patient's situation. These techniques may be accomplished with a variety of minimal access strategies and various graft and spacer technologies. The modern spine surgeon should be proficient in using all these options to treat the painful lumbar motion segment.

Humans↗
PubMed2005

Analysis of operative complications in a series of 471 anterior lumbar interbody fusion procedures.

STUDY DESIGN: This retrospective review compares the intraoperative and perioperative complications associated with the placement of threaded devices and nonthreaded devices used in anterior lumbar interbody fusions. OBJECTIVE: Anterior lumbar interbody fusion is a common procedure performed with either a nonthreaded device, such as a femoral ring, or a threaded device, such as with a cage or a bone dowel. SUMMARY OF BACKGROUND DATA: Many studies have been done detailing the fusion rates and biomechanical properties of both devices. However, few studies have been performed evaluating acute complications between the two device types. METHODS: A retrospective chart review was performed of 471 consecutive patients who underwent anterior lumbar interbody fusion: 243 with a nonthreaded interbody device and 228 with a threaded interbody device. Operative notes, anesthesia reports, discharge summaries, and follow-up notes were reviewed from 1992 to June 2002. The patients' demographics, diagnosis, number of levels fused, type of device used, length of hospital stay, and acute complications, either intraoperative or perioperative, were collected and analyzed. RESULTS: Approximately 4.8% of patients with a threaded type interbody device had an intraoperative complication whereas only 0.4% of patients with a nonthreaded type device had an intraoperative complication. There was a significant association between interbody device type (threaded vs. nonthreaded) and occurrence of an intraoperative complication (P = 0.0024). CONCLUSIONS: Placement of threaded devices, such as cages or bone dowels, was associated with a higher acute complication rate than was the placement of nonthreaded devices during anterior lumbar interbody fusion.

Adolescent↗
PubMed2005

Occipitocervical fixation: long-term results.

STUDY DESIGN: The study is a retrospective review of 58 patients who underwent occipitocervical fusion between 1997 and 2001. OBJECTIVES: Our objective is to study the clinical results after occipitocervical fixation with long-term follow-up and assess factors contributing to clinical success. METHODS: Data from patient charts, operative notes, physician office notes, and imaging studies were incorporated in the study. Myelopathy was assessed using a Nurick scale for preoperative and postoperative evaluation. Fusion was assessed using cervical plane films with flexion and extension views. RESULTS: Mean follow-up was 36 months, with all patients having a greater than 1-year follow-up. The most common pathology was congenital cranial settling (41%) followed by trauma (22%) and rheumatoid arthritis (17%). Myelopathy was the most common presentation (62%) followed by pain (28%). A successful fusion occurred in 48 out of 51 patients (94%). Symptoms improved in 86% of patients, whereas 35% improved 1 Nurick grade. Complications occurred in 30% of patients. The cervical wound infection rate was 5%. The rate of adjacent level degeneration was 7%. The mortality rate was 1.7%. CONCLUSIONS: Occipitocervical instrumentation allows for very high fusion rates without the need for halo vest immobilization. All patients with successful fixation have pain resolution. Myelopathy improves in most patients, whereas one-third of patients demonstrate dramatic improvement.

Adolescent↗
PubMed2005

Minimally invasive, endoscopic, internal thoracoplasty for the treatment of scoliotic rib hump deformity: technical note.

OBJECTIVE: Patients with idiopathic scoliosis often have a noticeable rib deformity that frequently persists after corrective surgery. Open thoracoplasty has been the traditional method of reducing rib deformity. Recently, however, video-assisted thoracoscopy (VATS) has been used to perform thoracoplasty. There have been no long-term follow-up studies on VATS thoracoplasty, nor have there been outcome scores to assess the results of thoracoplasty procedures. We present our experience using VATS thoracoplasty with long-term follow-up and propose an outcome grading system for thoracoplasty. METHODS: Between 1998 and 2000, four patients (age range, 14-53 yr) underwent VATS thoracoplasty for significant rib hump deformity (mean height, 5 cm; range, 4-6 cm) associated with idiopathic scoliosis. All patients had four rib segments resected during the VATS thoracoplasty procedure. Three of the four patients also underwent anterior thoracic release and discectomy during the procedure. RESULTS: Patients were followed for a mean of 40 months after surgery (range, 33-50 mo). There were no intraoperative or postoperative complications. Outcomes were assessed using a patient questionnaire with our new thoracoplasty grading system. All patients were pleased that they had chosen to have VATS internal thoracoplasty. Based on our new grading system, two patients had an excellent outcome and two had a good outcome. CONCLUSION: VATS provides an alternative, minimally invasive route to perform thoracoplasty. VATS incisions are much smaller and more cosmetically appealing than open thoracoplasty incisions. Long-term follow-up indicates good to excellent patient outcomes.

Adolescent↗
PubMed2005

The mini-open transforaminal lumbar interbody fusion.

The mini-open approach for transforaminal lumbar interbody fusion is described in detail. Operating room setup and surgical positioning are demonstrated. Our methods of retractor placement and techniques for optimal surgical exposure are discussed. The surgical technique used for decompression and fusion is presented in detail. The surgical pearls and pitfalls of the mini-open TLIF are described and illustrated.

Humans↗
PubMed2005

Anterior cervical discectomy and fusion involving a polyetheretherketone spacer and bone morphogenetic protein.

OBJECT: The authors reviewed clinical and radiographic outcomes in patients who had undergone anterior cervical discectomy and fusion (ACDF) involving the placement of polyetheretherketone (PEEK) spacers filled with recombinant human bone morphogenetic protein (rhBMP)-2. METHODS: Data obtained in 24 cases were retrospectively evaluated. The follow-up period ranged from 12 to 16 months (mean 13 months). Fifteen patients presented with radiculopathy, eight with myeloradiculopathy, and one with quadriparesis. Single-level ACDF was performed in 12 patients, two-level ACDF in nine, and three-level ACDF in three. Clinical outcomes were assessed using Odom criteria, and fusion was assessed by examining flexion-extension radiographs and computerized tomography scans in cases in which arthrodesis was questionable. Follow-up data were available for 23 patients. One patient died of medical complications unrelated to surgery 4 weeks after ACDF. Clinical outcomes were rated as good/excellent in 22 patients (95%) and fair in one (5%). Solid radiographically documented fusion, with evidence of solid bridging bone and no instability on flexion-extension x-ray films, was present in all cases. Complications included transient recurrent laryngeal nerve injury in one case, transient C-5 paresis in one, cerebrospinal fluid leakage in one, and transient dysphagia in two. CONCLUSIONS: Analysis of the results indicated that ACDF involving an rhBMP-2-filled PEEK spacer leads to good clinical outcomes (by Odum criteria) and solid fusion (even in multilevel cases) while avoiding the complications associated with harvesting iliac crest bone grafts.

Adult↗
PubMed2005

Atlantoaxial fixation: overview of all techniques.

Over the past century, steady advances have been made in fixating an unstable atlantoaxial complex. Current options for fixation of the atlantoaxial complex include posterior clamps, posterior wiring techniques, C1-C2 transarticular screw fixation, posterior C1 lateral mass screw with C2 pars or pedicle screw fixation, and anterior transoral C1 lateral mass to C2 vertebral body fixation.

Atlanto-Axial Joint↗
PubMed2005

Transoral odontoidectomy.

The transoral approach for odontoidectomy is described in detail, and the operating room setup and surgical positioning are demonstrated. We also discuss our methods of retractor placement and techniques for optimal surgical exposure. The microsurgical technique used for decompression is presented in detail. The surgical pearls and pitfalls of transoral odontoidectomy, learned from a 70-case experience, are described and illustrated.

Functional Laterality↗
PubMed2004

Similarity in the fatigue behavior of trabecular bone across site and species.

Within the context of improving knowledge of the structure-function relations for trabecular bone for cyclic loading, we hypothesized that the S-N curve for cyclic compressive loading of trabecular bone, after accounting for differences in monotonic strength behavior, does not depend on either site or species. Thirty-five cores of fresh-frozen elderly human vertebral trabecular bone, harvested from nine donors (mean+/-S.D., age=74+/-17 years), were biomechanically tested in compression at sigma/E(0) values (ratio of applied stress to pre-fatigue elastic modulus) ranging from 0.0026 to 0.0070, and compared against literature data (J. Biomech. Eng. 120 (1998) 647-654) for young bovine tibial trabecular bone (n=37). As reported for the bovine bone, the number of cycles to failure for the human vertebral bone was related to sigma/E(0) by a power-law relation (r(2)=0.54, n=35). Quantitative comparison of these data against those reported for the bovine bone supported our hypothesis. Namely, when the differences in mean monotonic yield strain between the two types of bone were accounted for, a single S-N curve worked well for the pooled data (r(2)=0.75, n=72). Since elderly human vertebral and young bovine tibial trabecular bone represent two very different types of trabecular bone in terms of volume fraction and architecture, these findings suggest that the dominant failure mechanisms in trabecular bone for cyclic loading occur at the ultrastructural level.

Adaptation, Physiological↗
PubMed2004

Split spinal cord malformation in an elderly patient: case report.

Split spinal cord malformations (SCM) typically present in childhood and rarely in adulthood. Very little is known about the SCMs in the elderly, and the diagnosis can be easily missed. A 73-year-old woman with a childhood history of scoliosis and late ambulation milestones presented with a 2-year history of worsening low back pain and progressive difficulty walking. She had a mild gait disturbance with 4/5 weakness in left ankle dorsiflexion. Magnetic resonance imaging revealed a bifid spinal cord contained in a single thecal sac and a tethered cord with low-lying conus at L3. The patient was taken to the operating room and a soft-tissue median septum, as well as all other adhesions, was removed. The filum terminale was identified, coagulated, and divided. Six weeks later, the patient reported decreased back pain, improvement in ambulation, and markedly decreased used of narcotics for her back and leg pain. Her left ankle dorsiflexion strength improved to 4+/5. This patient had two hemicords encased in a single dural tube separated by a nonrigid, fibrous median septum and an associated tethered cord. Adult presentation of SCM is extremely rare. This case highlights the need to consider split cord malformation and tethered cord in the differential diagnosis not only for adults but also the elderly presenting with back pain, scoliosis, and difficulty walking.

Aged↗
PubMed2004

Posterior cervical laminoplasty using a new plating system: technical note.

BACKGROUND: Laminoplasty is well described in the Japanese literature as a surgical option for treating ossification of the posterior longitudinal ligament (OPLL). The open door technique has gained increasing popularity in the United States and Europe to treat not only OPLL but also cervical stenotic myelopathy. An obstacle to its widespread use is the lack of a suitable fixation plate to adequately secure the fractured lamina to the lateral mass. Our objective was to demonstrate the advantages of a novel miniplate (Ti-Mesh LP system; Medtronic Sofamor Danek, Memphis, TN, USA) that is ideally suited for fixing the lamina to the lateral mass. METHODS: We used the Ti-Mesh LP miniplate system to perform laminoplasties on five patients, all male, with a mean preoperative Nurick score of 2.8. Four patients had congenital cervical stenosis with myelopathy and one had OPLL. Open door laminoplasties were performed on all patients. The plates were implanted with a claw positioned on the trapdoor lamina and a flat plate on the lateral mass. RESULTS: The system was implanted successfully in all patients. The mean number of levels fixated was 4.4. There were no intraoperative or postoperative complications after >5 months follow-up. CONCLUSIONS: The new Ti-Mesh LP cranial miniplate and screw system facilitates posterior cervical laminoplasty procedures by eliminating the need to contour cranial miniplates for use in the cervical spine. Its unique claw construct and angled design are ideal for holding a trapdoor laminoplasty in the open position. We have used this system successfully and without complications to perform decompressive posterior cervical laminoplasties in five patients.

Aged↗
PubMed2004

Contribution of recombinant human bone morphogenetic protein-2 to the rapid creation of interbody fusion when used in transforaminal lumbar interbody fusion: a preliminary report. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2004.

OBJECT: The authors compared fusion rates in transforaminal lumbar interbody fusion (TLIFs) when using either autograft or bone morphogenetic protein (BMP) placed in the interbody space. METHODS: Between September 2002 and December 2003, the authors performed 44 TLIF operations. Follow-up data were available for 40 patients. Of the 40 procedures, 19 involved cages filled with iliac crest autograft (Group 1) and 21 involved cages filled with a medium kit of recombinant human (rh) BMP-2 (Group 2). In all Group 2 patients, one BMP sponge was placed anterior to the cage and another was placed within the cage. In 12 of the Group 2 patients, iliac crest autograft was placed posterior to the BMP-filled cage (Group 2A). In the remaining nine Group 2 patients, only local autograft was placed posterior to the BMP-filled cage (Group 2B). Assessment of fusion was performed using dynamic radiography at 3-month intervals. Outcomes were assessed using the Prolo Scale, and iliac crest donor site pain was measured using a Visual Analog Scale (VAS). The mean follow-up period was 9 months (range 3-18 months). In Group 1 patients, one pseudarthrosis was detected. In Group 2 patients, dynamic radiography demonstrated solid fusion in all patients except one in Group 2B. Fifty-eight percent of patients in whom iliac crest autograft was used complained of donor site pain 6 months after surgery (5 of 10 points on the VAS). Symptomatic foraminal bone formation was not observed in any Group 2 patient. CONCLUSIONS: The use of rhBMP-2 is safe in TLIFs when the sponges are placed away from the dura mater, and BMP promotes a more rapid fusion than iliac crest autograft alone. The use of rhBMP-2 in combination with local autograft is an excellent option for promoting solid fusion with TLIF, and it eliminates the possibility of iliac donor site pain.

Adult↗