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Q Fong

Publications and source records attributed to Q Fong.

4 recordsLinked to original sources
PubMed2000

Clonal characterization of a bipotent T cell and NK cell progenitor in the mouse fetal thymus.

We recently described a population of fetal thymocytes with a CD117+NK1.1+CD90lowCD25- phenotype, which were shown to contain committed T cell and NK cell progenitors. However, the characterization of a single cell with a restricted T and NK cell precursor potential was lacking. Here, using an in vitro model for T and NK cell differentiation, we provide conclusive evidence demonstrating the existence of a clonal lineage-restricted T and NK cell progenitor. These results establish that fetal thymocytes with a CD117+NK1.1+CD90lowCD25- phenotype represent bipotent T and NK cell progenitors.

Animals↗
PubMed1993

Mutation of the gene for the human lysosomal serine protease cathepsin G is not the cause of aberrant APP processing in familial Alzheimer disease.

Recent genetic linkage studies have implicated a gene on chromosome 14 in the pathogenesis of FAD. The identity of this gene remains unknown but it has been speculated that it may be involved in the cellular processing of the amyloid precursor protein (APP). We have analyzed the nucleotide sequence of the entire open reading frame of the cathepsin G gene located on chromosome 14q. No mutations were observed, suggesting that defects in this lysosomal protease are not responsible for aberrant accumulation of proteolytic products of APP in FAD brain tissue.

Alzheimer Disease↗
PubMed1989

A bacterial lipopolysaccharide emulsifier.

When Acinetobacter sp. was grown in a variety of carbon sources such as alcohols, vegetable oils or hydrocarbons, exolipopolysaccharide was produced. Discussed in this report are the optimal conditions for the production of this exolipopolysaccharide, including different carbon sources, nitrogen sources, divalent magnesium ion, and the addition of antibiotics. The content of the exolipopolysaccharide was assayed by emulsification turbidimetry. The investigation indicated that this exolipopolysaccharide exhibited a good emulsifying ability and emulsion stabilizing activity. It is a polymeric bioemulsifier.

Acinetobacter↗