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Biomedical subjects

Q Ji

Publications and source records attributed to Q Ji.

46 records · Page 3Linked to original sources
PubMed1997

[Accumulation and excretion of fluorine and effect of selenium on them in rats with chronic fluorosis].

2 groups of Wistar rats with chronic fluorosis were duplicated with 30 and 50 mg/L fluorine (F) in drinking water. 2. 0 mg/kg selenium (Se) in fodder was supplemented in the other 2 groups of rats with fluorosis. The amount of drinking water and diet, the excretion of urine and the contents of urine F were tendentiously surveyed every month in one year and then, intake and excretion of F were calculated per day. The contents of Se in urine, liver and serum and F in bone, liver, kidney and serum were measured in the 4th, 8th, and 14th month. The results showed that F absorption increased and F excretion/F absorption rate decreased in 2 groups of rats with fluorosis compared with control group and there were positive correlations between concentration of urine F and water F, as well as concentration of F urine and time of drinking F water. The accumulation of F in bone and liver occurred in the middle period of fluorosis and then, the increase of serum F was observed in the late period of fluorosis in 2 groups of rats with fluorosis. After supplement of Se, urine, liver and serum Se ascended. At the same time, state of eating and drinking improved, the weight rose and the amount of urine excretion heightened, as well as there was an increase of urine F and excretion F/absorption F rate and there was a decrease of bone, live, kidney and serum F in rat of Se supplementation with fluorosis compared with non-Se groups.

Animals↗
PubMed1997

[Localization of PTH gene on pig chromosome 14q25-q28 by in situ hybridization].

The human parathyroid hormone (PTH) genic DNA, as a probe, was labelled with tritium(3H) using nick translation and random oligonucleotide primers methods. Metaphase chromosomal G-bands were prepared from cultured blood lymphocytes of domestic pig. After in situ hybridization and autoradiographly, the number of silver grains on every chromosome was calculated. The result showed that PTH gene is located at chromosome 14q25-q28. The relevent points of this study are discussed.

Animals↗
PubMed1996

Vicia faba root tip micronucleus test on the mutagenicity of water-soluble contents of cigarette smoke.

The possible mutagenicity of the water-soluble contents of cigarette smoke (WSCS) was evaluated by using the Vicia faba root tip micronucleus test. The results showed significant changes in micronucleus frequency which were caused by each different concentration of WSCS. This indicates that the Vicia faba root tip micronucleus test might be used as one kind of mutagenic detection method for cigarette smoke. A comparative evaluation on the mutagenicity of 10 brands of cigarettes was carried out. Results confirmed that various degrees of mutagenicity were found for all of the brand cigarettes, among them, Huaihai was the highest, while Camellia was the lowest. The micronucleus frequencies were reduced by adding tea polyphenol, nicotinamide adenine, vitamin C and sodium selenite to the WSCS. The results suggest that these added substances might reduce the genetic injury induced by cigarette smoke.

Air Pollutants↗
PubMed1996

[Factors affecting prognosis of papillary thyroid carcinoma with bilateral cervical lymph node metastases].

One hundred thirty nine cases of papillary thyroid carcinoma with bilateral lymph node metastases were reviewed. They were surgically treated at the Cancer Hospital of Shanghai Medical University in the years from 1956 through 1990. There were 73 men and 66 women with a median age of 35 (range 11-70) years. The median follow-up period was 11 years. Kaplan-Meier survival curves were calculated for the population. The overall survival rate was 94.7% at 5 years, 85.9% at 10 years, and 82.3% at 15 years. In univariate analysis, factors influencing prognosis are age at diagnosis, tumor size, extrathyroidal invasion, residual tumor and thoroughness of excision. When Cox proportional risk model was applied to analyze the survival data, factors of survival significance are the age at diagnosis and thoroughness of excision.

Adenocarcinoma, Papillary↗
PubMedDate not supplied

Layer differences in the effect of monocular vision in light- and dark-reared kittens.

We compared the effect of 2 days of monocular vision on the ocular dominance of cells in the visual cortex of light-reared kittens with the effect in dark-reared kittens at 6, 9, and 14 weeks of age, and analyzed the results by layer. The size of the ocular-dominance shift declined with age in all layers in light-reared animals. There was not a large change in the ocular-dominance shift with age in dark-reared animals in any layer, suggesting that dark rearing largely keeps the cortex in the immature 6-week state until 14 weeks or longer, although there was a slight decrease in layers II, III, and IV, and a slight increase in layers V and VI. At 14 weeks, the difference between light- and dark-reared animals was smallest in layer IV, larger in layers II/III, and largest in layers V/VI, suggesting that dark rearing has a large effect on intracortical synapses and a small effect on geniculocortical synapses. There was a significant ocular-dominance shift in layer IV at 14 weeks of age in both light- animals and dark-reared animals, showing that the critical period for ocular-dominance plasticity is not ended at this age. While the ocular-dominance shift after 26 h of monocular deprivation in 6-week animals was similar in light- and dark-reared animals, after 14 h it was smaller in dark-reared animals, showing that ocular-dominance changes occur more slowly in dark-reared animals at this age, in agreement with Mower (1991). Increases in selectivity for axis of movement after 26 h of monocular vision were seen in dark-reared animals at 6 weeks of age, but not at 9 or 14 weeks of age, showing that the critical period for axial selectivity ends earlier than the critical period for ocular dominance in dark-reared animals, as it does in light-reared animals.

Aging↗