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Biomedical subjects

Q Tan

Publications and source records attributed to Q Tan.

29 records · Page 2Linked to original sources
PubMed1999

[The treatment of 432 patients with pituitary adenomas via transsphenoidal approach].

OBJECTIVE: To study some clinical features of 432 cases of pituitary adenomas treated by transsphenoidal microsurgery between July 1982 and October 1996. METHODS: Pathological examination, immunohistochemical examination and electronmicroscopic examination were done in 424, 29 and 103 cases respectively. RESULTS: Hyperprolactinemia was found in many so-called non-functioning adenomas besides in prolactinomas. The dura maters were invaded by tumors in 78 cases (the incidence of dural invasion was 65.5%). CONCLUSIONS: Hyperprolactinemia is not peculiar to prolactinomas, and differential diagnosis is necessary when hyperprolactinemia exists. The involvement of the dura mater of sellar floor is an important mark that the adjacent tissues were invaded by pituitary adenomas. The outcome of surgical treatment is significantly different between the patients with dural invasion and without invasion.

Adenoma↗
PubMed1998

[Endovascular treatment of carotid-cavernous sinus fistulae].

OBJECTIVE: To treat carotid-cavernous sinus fistulae mmunications between 43 patients with endovascular procedure. METHOD: Of the 43 patients 37 were male and 6 female. Traumatic and spontaneous CCF were noted in 39 and 4 patients respectively. 36 patients with CCF were given ICA alone, both internal and external carotid arteries in 7. Fistulae occlusion in 31 patients and ICA obliteration in 12 patients were achieved with transarterial detachable balloon technique. External carotid feeding arteries were embolized with silk suture in 7 patients. RESULT: Angiographic and clinical cure wer obtained in 39 patients and improved in 4. One patient was complicated by hemiplegia postoperatively. CONCLUSION: Endovascular balloon embolization is the first method of choice in dealing with carotid-cavernous fistulae.

Adolescent↗
PubMed1998

[Effect of AHMED valve implantation surgery for the treatment of neovascular glaucoma].

PURPOSE: To evaluate the efficacy of the valve implantation for the treatment of neovascular glaucoma. METHODS: 15 cases (15 eyes) neovascular glaucoma were treated with AHMED valve implantation surgery, and followed up for 6 to 42 months. RESULTS: The IOP of the cases is lowered from 6.01 +/- 1.28 kPa (1 kPa = 7.5 mmHg) preoperatively to 1.96 +/- 0.68 kPa postoperatively. The success rate was 80.0% (The criteria of success is 0.80 kPa < or = IOP < or = 2.80 kPa and without severe complication that influence the visual acuity). The common postoperative complications included hyphema, shallow anterior chamber. CONCLUSION: The AHMED valve implantation surgery can lower the IOP, increase the operative success rate and preserve the visual function effectively. It is regarded to be an effective, safe method to treat neovascular glaucoma.

Adult↗
PubMed1997

Can superoxide dismutase prevent postburn dermal ischemia?

Decreasing progressive dermal ischemia after burning could theoretically limit the amount of skin necrosis. It is controversial whether the use of free radical scavengers could prevent the progressive dermal ischemia of the postburn stasis zone. We evaluated the effect of superoxide dismutase (SOD) on preventing postburn dermal ischemia in animal models by the India ink perfusion and skin transparent preparation techniques. The closely clipped backs of guinea-pigs were bathed in 75 degrees C water for 10 s. Within 5 min postburn, SOD-treated groups were administered SOD (10,000 u/kg) intra-peritoneally every 6 h. All animals were perfused with 70 per cent India ink via cervical artery cannula by 16 kPa constant pressure at 0, 8, 16, 24 h postburn, and the skin transparent preparations were made, while the level of malonyl dialdehyde (MDA) in skin tissue was assessed. The results showed that with prolongation of postburn time, the rate of filling of India ink in skin capillary plexuses decreased gradually (p < 0.01). MDA increased continuously, which was related to postburn dermal ischemia (r = 0.689, p < 0.01). Though the level of MDA decreased in SOD-treated groups, the India ink filling rates showed no significant difference between controls and experimental groups (p > 0.05). The results were also confirmed by observation of skin transparent preparations and TEM. This study suggests that superoxide dismutase fails to prevent progressive dermal ischemia after burning.

Animals↗
PubMed1997

[Polymorphism of group specific component (Gc) in nine Han subpopulations in China].

Isoelectric focusing (IEF) followed by immunofixation in thin layer polyacrylamide gels (pH4-6) was used to analyse the Gc subtypes of 1841 individuals from nine Han geographically distributed populations in China. The Gc1F gene frequencies in these Han subpopulations from Lanzhou, Huhhot, Harbin, Xi'an, Zhengzhou, Chengdu, Guiyang, Zhangzhou and Harras in Guangdong Province were 0.3905, 0.4333, 0.4193, 0.4146, 0.4182, 0.4035, 0.4045, 0.4381 and 0.4347 respectively; Gc1S were 0.3071, 0.2190, 0.2734, 0.2261, 0.2182, 0.2871, 0.2889, 0.2738 and 0.2764 respectively; Gc2 were 0.2786, 0.3357, 0.2917, 0.3367, 0.3295, 0.2896, 0.3065, 0.2667, and 0.2814 respectively. GcV were 0.0238, 0.0119, 0.0156, 0.0226, 0.0341, 0.0198, 0.0000, 0.0214 and 0.0075 respectively. The results of present study indicated a clear cline of linear change from north to south China in allelic frequency at the Group-Specific Component (Gc) locus among nine Chinese populations. Three alleles, Gc1F, Gc2 and GcV, showed frequencies varying from 0.3905 to 0.4381, from 0.2786 to 0.3367 and from nil to 0.0341, respectively, over these geographical subpopulations. In addition, some rare variant phenotypes of Gc in Chinese populations were discussed.

China↗
PubMed1996

[Anatomy of the endolymphatic sac and its clinical significance].

Using 28 formalin fixed temporal bones and materials of 26 cases of endolymphatic surgery for menieres' disease, the location, vascular distribution and size of the endolyphatic sac (ELS) were investigated. ELS were measured with surgical microscope in all the cadaver specimen with a mean length of 6.9393 +/- 2.0429 mm and mean width of 5.8821 +/-1.6522 mm. All the specimens showed no clear capillary distribution. Only in 24 of the 26 ELS surgeries for Menieres' disease the ELS were found. The mean length was 6.8125 +/- 2.2449 mm, the mean width 5.6666 +/- 1.5084 mm and the vascular distribution was unclear in 29% of the cases. It was found that the ELS usually located at the Donaldson line, and moved downward in the under-developed mastoid with smaller size.

Adult↗
PubMed1990

[Distribution of 8 blood group systems in Han ethnic group of Fujian Province, China].

The distribution of 19 red cell's antigens of 8 blood group systems in Han ethnic group in Fujian province, China was investigated. The gene and haloptype frequencies were as follows: p = 0.1936, q = 0.1766, r = 0.6298; p1 = 0.1427; Dia = 0.2830; m = 0.5695, n = 0.4305, S = 0.0339, s = 0.9661, MS = 0.0200, NS = 0.0139, Ms = 0.5500, Ns = 0.4161; Fya = 0.8817; Jka = 0.4767; D = 0.9314, C = 0.7617, E = 0.2357, r' = 0.0686, R1 = 0.6352, R2 = 0.1970, R0 = 0.0605, Rz = 0.0388. Le (a +) phenotype frequency = 7.94%.

Blood Group Antigens↗
PubMed1990

[Study on chromosome c-banding in Paragonimus westermani: comparison of the diploid and triploid types].

A comparative study was performed in detail on the c-band pattern of diploid and triploid types of Paragonimus westermani by using BSG method. The result revealed that both types of P. westermani possessed the identical c-band pattern and c-band polymorphism. Thus the authors considered that the triploid type of P. westermani might be an autotriploid. The polymorphism of c-band pattern in diploid and the combination of homologous chromosomes with c-band polymorphism in triploid were reported for the first time.

Animals↗